LuCaP Prostate Cancer Patient‐Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease an­­d Serve as Models for Evaluating Cancer Therapeutics von Nguyen, Holly M., Vessella, Robert L., Morrissey, Colm, Brown, Lisha G., Coleman, Ilsa M., Higano, Celestia S., Mostaghel, Elahe A., Zhang, Xiaotun, True, Lawrence D., Lam, Hung‐Ming, Roudier, Martine, Lange, Paul H., Nelson, Peter S., Corey, Eva

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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant von Sun, Shihua, Sprenger, Cynthia C T, Vessella, Robert L, Haugk, Kathleen, Soriano, Kathryn, Mostaghel, Elahe A, Page, Stephanie T, Coleman, Ilsa M, Nguyen, Holly M, Sun, Huiying, Nelson, Peter S, Plymate, Stephen R

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SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer von Zhang, Xiaotun, Coleman, Ilsa M, Brown, Lisha G, True, Lawrence D, Kollath, Lori, Lucas, Jared M, Lam, Hung-Ming, Dumpit, Ruth, Corey, Eva, Chéry, Lisly, Lakely, Bryce, Higano, Celestia S, Montgomery, Bruce, Roudier, Martine, Lange, Paul H, Nelson, Peter S, Vessella, Robert L, Morrissey, Colm

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Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer von Lim, Yiting, Arora, Sonali, Schuster, Samantha L., Corey, Lukas, Fitzgibbon, Matthew, Wladyka, Cynthia L., Wu, Xiaoying, Coleman, Ilsa M., Delrow, Jeffrey J., Corey, Eva, True, Lawrence D., Nelson, Peter S., Ha, Gavin, Hsieh, Andrew C.

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Exploitation of CD133 for the Targeted Imaging of Lethal Prostate Cancer von Glumac, Paige M., Gallant, Joseph P., Shapovalova, Mariya, Li, Yingming, Murugan, Paari, Gupta, Shilpa, Coleman, Ilsa, Nelson, Peter S., Dehm, Scott M., LeBeau, Aaron M.

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Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression : Therapeutic implications for castration-resistant prostate cancer von MOSTAGHEL, Elahe A, PAGE, Stephanie T, BREMNER, William J, GLEAVE, Martin E, NELSON, Peter S, LIN, Daniel W, FAZLI, Ladan, COLEMAN, Iisa M, TRUE, Lawrence D, KNUDSEN, Beatrice, HESS, David L, NELSON, Colleen C, MATSUMOTO, Alvin M

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Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature von Labrecque, Mark P., Brown, Lisha G., Coleman, Ilsa M., Nguyen, Holly M., Lin, Daniel W., Corey, Eva, Nelson, Peter S., Morrissey, Colm

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A Novel Flavonoid Composition Targets Androgen Receptor Signaling and Inhibits Prostate Cancer Growth in Preclinical Models von Mamouni, Kenza, Zhang, Shumin, Li, Xin, Chen, Yanhua, Yang, Yang, Kim, Jaeah, Bartlett, Michael G., Coleman, Ilsa M., Nelson, Peter S., Kucuk, Omer, Wu, Daqing

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Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4 von Coleman, Daniel J., Sampson, David A., Sehrawat, Archana, Kumaraswamy, Anbarasu, Sun, Duanchen, Wang, Yuzhuo, Schwartzman, Jacob, Urrutia, Joshua, Lee, Ahn R., Coleman, Ilsa M., Nelson, Peter S., Dong, Xuesen, Morrissey, Colm, Corey, Eva, Xia, Zheng, Yates, Joel A., Alumkal, Joshi J.

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Third generation quinoline-3-carboxamide transcriptional disrupter of HDAC4, HIF-1α, and MEF-2 signaling for metastatic castration-resistant prostate cancer von Isaacs, John T, Dalrymple, Susan L, Antony, Lizamma, Marc Rosen, David, Coleman, Ilsa M, Nelson, Peter S, Kostova, Maya, Murray, Iain A, Perdew, Gary H, Denmeade, Samuel R, Akinboye, Emmanuel S, Brennen, W Nathaniel

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The effects of aging on the molecular and cellular composition of the prostate microenvironment von Bianchi-Frias, Daniella, Vakar-Lopez, Funda, Coleman, Ilsa M, Plymate, Stephen R, Reed, May J, Nelson, Peter S

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Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate von Pascal, Laura E, True, Lawrence D, Campbell, David S, Deutsch, Eric W, Risk, Michael, Coleman, Ilsa M, Eichner, Lillian J, Nelson, Peter S, Liu, Alvin Y

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Defining cellular population dynamics at single-cell resolution during prostate cancer progression von Germanos, Alexandre A, Arora, Sonali, Zheng, Ye, Goddard, Erica T, Coleman, Ilsa M, Ku, Anson T, Wilkinson, Scott, Song, Hanbing, Brady, Nicholas J, Amezquita, Robert A, Zager, Michael, Long, Annalysa, Yang, Yu Chi, Bielas, Jason H, Gottardo, Raphael, Rickman, David S, Huang, Franklin W, Ghajar, Cyrus M, Nelson, Peter S, Sowalsky, Adam G, Setty, Manu, Hsieh, Andrew C

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Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations von Bianchi-Frias, Daniella, Basom, Ryan, Delrow, Jeffrey J, Coleman, Ilsa M, Dakhova, Olga, Qu, Xiaoyu, Fang, Min, Franco, Omar E, Ericson, Nolan G, Bielas, Jason H, Hayward, Simon W, True, Lawrence, Morrissey, Colm, Brown, Lisha, Bhowmick, Neil A, Rowley, David, Ittmann, Michael, Nelson, Peter S

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VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer von Goel, Hira Lal, Chang, Cheng, Pursell, Bryan, Leav, Irwin, Lyle, Stephen, Xi, Hualin Simon, Hsieh, Chung-Cheng, Adisetiyo, Helty, Roy-Burman, Pradip, Coleman, Ilsa M, Nelson, Peter S, Vessella, Robert L, Davis, Roger J, Plymate, Stephen R, Mercurio, Arthur M

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Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis von Sung, Shian-Ying, Hsieh, Chia-Ling, Law, Andrew, Zhau, Haiyen E, Pathak, Sen, Multani, Asha S, Lim, Sharon, Coleman, Ilsa M, Wu, Li-Chin, Figg, William D, Dahut, William L, Nelson, Peter, Lee, Jae K, Amin, Mahul B, Lyles, Robert, Johnstone, Peter A J, Marshall, Fray F, Chung, Leland W K

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Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling von Bluemn, Eric G., Coleman, Ilsa M., Lucas, Jared M., Coleman, Roger T., Hernandez-Lopez, Susana, Tharakan, Robin, Bianchi-Frias, Daniella, Dumpit, Ruth F., Kaipainen, Arja, Corella, Alexandra N., Yang, Yu Chi, Nyquist, Michael D., Mostaghel, Elahe, Hsieh, Andrew C., Zhang, Xiaotun, Corey, Eva, Brown, Lisha G., Nguyen, Holly M., Pienta, Kenneth, Ittmann, Michael, Schweizer, Michael, True, Lawrence D., Wise, David, Rennie, Paul S., Vessella, Robert L., Morrissey, Colm, Nelson, Peter S.

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Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer von Labrecque, Mark P, Coleman, Ilsa M, Brown, Lisha G, True, Lawrence D, Kollath, Lori, Lakely, Bryce, Nguyen, Holly M, Yang, Yu C, da Costa, Rui M Gil, Kaipainen, Arja, Coleman, Roger, Higano, Celestia S, Yu, Evan Y, Cheng, Heather H, Mostaghel, Elahe A, Montgomery, Bruce, Schweizer, Michael T, Hsieh, Andrew C, Lin, Daniel W, Corey, Eva, Nelson, Peter S, Morrissey, Colm

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Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer von Brennen, W. Nathaniel, Zhu, Yezi, Coleman, Ilsa M., Dalrymple, Susan L., Antony, Lizamma, Patel, Radhika A., Hanratty, Brian, Chikarmane, Roshan, Meeker, Alan K., Zheng, S. Lilly, Hooper, Jody E., Luo, Jun, De Marzo, Angelo M., Corey, Eva, Xu, Jianfeng, Yegnasubramanian, Srinivasan, Haffner, Michael C., Nelson, Peter S., Nelson, William G., Isaacs, William B., Isaacs, John T.

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Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer von Sayar, Erolcan, Patel, Radhika A, Coleman, Ilsa M, Roudier, Martine P, Zhang, Ailin, Mustafi, Pallabi, Low, Jin-Yih, Hanratty, Brian, Ang, Lisa S, Bhatia, Vipul, Adil, Mohamed, Bakbak, Hasim, Quigley, David A, Schweizer, Michael T, Hawley, Jessica E, Kollath, Lori, True, Lawrence D, Feng, Felix Y, Bander, Neil H, Corey, Eva, Lee, John K, Morrissey, Colm, Gulati, Roman, Nelson, Peter S, Haffner, Michael C

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