Phosphoramidon, a metalloproteinase inhibitor, suppresses the secretion of endothelin-1 from cultured endothelial cells by inhibiting a big endothelin-1 converting enzyme von Ikegawa, Ruriko, Matsumura, Yasuo, Tsukahara, Yaeko, Takaoka, Masanori, Morimoto, Shiro

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Conversion of porcine big endothelin to endothelin by an extract from the porcine aortic endothelial cells von Matsumura, Yasuo, Ikegawa, Ruriko, Takaoka, Masanori, Morimoto, Shiro

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Conversion of big endothelin-1 to endothelin-1 by two types of metalloproteinases derived from porcine aortic endothelial cells von Matsumura, Yasuo, Ikegawa, Ruriko, Tsukahara, Yaeko, Takaoka, Masanori, Morimoto, Shiro

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Phosphoramidon prevents cerebral vasospasm following subarachnoid hemorrhage in dogs: The relationship to endothelin-1 levels in the cerebrospinal fluid von Matsumura, Yasuo, Ikegawa, Ruriko, Suzuki, Yasunori, Takaoka, Masanori, Uchida, Takeshi, Kido, Hideaki, Shinyama, Hiroshi, Hayashi, Kazutaka, Watanabe, Masahiro, Morimoto, Shiro

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Conversion of big endothelin-1 to endothelin-1 by two-types of metalloproteinases of cultured porcine vascular smooth muscle cells von Matsumura, Yasuo, Ikegawa, Ruriko, Tsukahara, Yaeko, Takaoka, Masanori, Morimoto, Shiro

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The endothelium-derived vasoconstrictor peptide endothelin inhibits renin release in vitro von Matsumura, Yasuo, Nakase, Kohji, Ikegawa, Ruriko, Hayashi, Kazutaka, Ohyama, Tadashi, Morimoto, Shiro

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Evidence for pepstatin-sensitive conversion of porcine big endothelin-1 to endothelin-1 by the endothelial cell extract von Ikegawa, Ruriko, Matsumura, Yasuo, Takaoka, Masanori, Morimoto, Shiro

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Phosphoramidon inhibits the generation of endothelin-1 from exogenously applied big endothelin-1 in cultured vascular endothelial cells and smooth muscle cells von Ikegawa, Ruriko, Matsumura, Yasuo, Tsukahara, Yaeko, Takaoka, Masanori, Morimoto, Shiro

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Potent Inhibition of the Proinflammatory Responses of Human Polymorphonuclear Cells by Prostaglandin E1 but not by PGI2 or Carbacyclin von Ikegawa, Ruriko, Imada, Teruaki, Murakami, Kazuki, Akira, Toshiaki, Nakamura, Norifumi

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Potent Inhibition of the Proinflammatory Responses of Human Polymorphonuclear Cells by Prostaglandin E 1 but not by PGI 2 or Carbacyclin von Ikegawa, Ruriko, Imada, Teruaki, Murakami, Kazuki, Akira, Toshiaki, Nakamura, Norifumi

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Metalloproteinase inhibitor prevents hepatic injury in endotoxemic mice von Murakami, Kazuki, Kobayashi, Fujio, Ikegawa, Ruriko, Koyama, Mamoru, Shintani, Nahoko, Yoshida, Tomohiro, Nakamura, Norifumi, Kondo, Takao

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Conversion of porcine big endothelin to endothelin by an extract from the cultured endothelial cells von Matsumura, Yasuo, Ikegawa, Ruriko, Takaoka, Masanori, Morimoto, Shiro

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Phosphoramidon inhibits the conversion of intracisternally administered big endothelin-1 to endothelin-1 von Shinyama, Hiroshi, Uchida, Takeshi, Kido, Hideaki, Hayashi, Kazutaka, Watanabe, Masahiro, Matsumura, Yasuo, Ikegawa, Ruriko, Takaoka, Masanori, Morimoto, Shiro

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Pepsin, an aspartic protease, converts porcine big endothelin to 21-residue endothelin von Takaoka, Masanori, Takenobu, Yoshifumi, Miyata, Yasushi, Ikegawa, Ruriko, Matsumura, Yasuo, Morimoto, Shiro

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N-Ethylmaleimide differentiates endothelin converting activity by two types of metalloproteinases derived from vascular endothelial cells von Matsumura, Yasuo, Ikegawa, Ruriko, Tsukahara, Yaeko, Takaoka, Masanori, Morimoto, Shiro

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Endothelin immunoreactivity in medium from cultured porcine aortic endothelial cells correlates with the biological activity von Matsumura, Yasuo, Ikegawa, Ruriko, Ohyama, Tadashi, Hayashi, Kazutaka, Shiro, Morimoto

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Conversion of porcine big endothelin to endothelin by pepsin von Takaoka, Masanori, Takenobu, Yoshifumi, Miyata, Yasushi, Ikegawa, Ruriko, Matsumura, Yasuo, Morimoto, Shiro

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The endothelium-derived vasoconstrictor peptide endothelin inhibits renin release from rat kidney cortical slices von Matsumura, Yasuo, Nakase, Kohji, Ikegawa, Ruriko, Hayashi, Kazutaka, Ohyama, Tadashi, Morimoto, Shiro

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Evidence for phosphoramidon-sensitive conversion of big endothelin-1 to endothelin-1 in isolated rat mesenteric artery von Hisaki, Kazuhiro, Matsumura, Yasuo, Ikegawa, Ruriko, Nishiguchi, Sumika, Hayashi, Kazutaka, Masanori, Takaoka, Morimoto, Shiro

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Proteolytic processing of porcine big endothelin-1 catalyzed by cathepsin D von Takaoka, Masanori, Hukumori, Yuriko, Shiragami, Kazushi, Ikegawa, Ruriko, Matsumura, Yasuo, Morimoto, Shiro

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