Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death von Wen, Xinmei, Tan, Wenzhi, Westergard, Thomas, Krishnamurthy, Karthik, Markandaiah, Shashirekha S., Shi, Yingxiao, Lin, Shaoyu, Shneider, Neil A., Monaghan, John, Pandey, Udai B., Pasinelli, Piera, Ichida, Justin K., Trotti, Davide

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Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons von Son, Esther Y., Ichida, Justin K., Wainger, Brian J., Toma, Jeremy S., Rafuse, Victor F., Woolf, Clifford J., Eggan, Kevin

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CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity von Kramer, Nicholas J., Haney, Michael S., Morgens, David W., Jovičić, Ana, Couthouis, Julien, Li, Amy, Ousey, James, Ma, Rosanna, Bieri, Gregor, Tsui, C. Kimberly, Shi, Yingxiao, Hertz, Nicholas T., Tessier-Lavigne, Marc, Ichida, Justin K., Bassik, Michael C., Gitler, Aaron D.

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ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids von Bowles, Kathryn R., Silva, M. Catarina, Whitney, Kristen, Bertucci, Taylor, Berlind, Joshua E., Lai, Jesse D., Garza, Jacob C., Boles, Nathan C., Mahali, Sidhartha, Strang, Kevin H., Marsh, Jacob A., Chen, Cynthia, Pugh, Derian A., Liu, Yiyuan, Gordon, Ronald E., Goderie, Susan K., Chowdhury, Rebecca, Lotz, Steven, Lane, Keith, Crary, John F., Haggarty, Stephen J., Karch, Celeste M., Ichida, Justin K., Goate, Alison M., Temple, Sally

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RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats von Yamada, Shizuka B., Gendron, Tania F., Niccoli, Teresa, Genuth, Naomi R., Grosely, Rosslyn, Shi, Yingxiao, Glaria, Idoia, Kramer, Nicholas J., Nakayama, Lisa, Fang, Shirleen, Dinger, Tai J. I., Thoeng, Annora, Rocha, Gabriel, Barna, Maria, Puglisi, Joseph D., Partridge, Linda, Ichida, Justin K., Isaacs, Adrian M., Petrucelli, Leonard, Gitler, Aaron D.

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Small Molecules Take a Big Step by Converting Fibroblasts into Neurons von Babos, Kimberley, Ichida, Justin K.

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ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD von Moore, Stephen, Alsop, Eric, Lorenzini, Ileana, Starr, Alexander, Rabichow, Benjamin E., Mendez, Emily, Levy, Jennifer L., Burciu, Camelia, Reiman, Rebecca, Chew, Jeannie, Belzil, Veronique V., W. Dickson, Dennis, Robertson, Janice, Staats, Kim A., Ichida, Justin K., Petrucelli, Leonard, Van Keuren-Jensen, Kendall, Sattler, Rita

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The C9ORF72 repeat expansion alters neurodevelopment von Hendricks, Eric, Quihuis, Alicia M., Hung, Shu-Ting, Chang, Jonathan, Dorjsuren, Nomongo, Der, Balint, Staats, Kim A., Shi, Yingxiao, Sta Maria, Naomi S., Jacobs, Russell E., Ichida, Justin K.

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Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State von Askary, Amjad, Mork, Lindsey, Paul, Sandeep, He, Xinjun, Izuhara, Audrey K., Gopalakrishnan, Suhasni, Ichida, Justin K., McMahon, Andrew P., Dabizljevic, Sonja, Dale, Rodney, Mariani, Francesca V., Crump, J. Gage

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The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease von Bakkar, Nadine, Starr, Alexander, Rabichow, Benjamin E., Lorenzini, Ileana, McEachin, Zachary T., Kraft, Robert, Chaung, Matthew, Macklin-Isquierdo, Sam, Wingfield, Taylor, Carhart, Briggs, Zahler, Nathan, Chang, Wen-Hsuan, Bassell, Gary J., Betourne, Alexandre, Boulis, Nicholas, Alworth, Samuel V., Ichida, Justin K., August, Paul R., Zarnescu, Daniela C., Sattler, Rita, Bowser, Robert

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Motoneurons derived from induced pluripotent stem cells develop mature phenotypes typical of endogenous spinal motoneurons von Toma, Jeremy S, Shettar, Basavaraj C, Chipman, Peter H, Pinto, Devanand M, Borowska, Joanna P, Ichida, Justin K, Fawcett, James P, Zhang, Ying, Eggan, Kevin, Rafuse, Victor F

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Effect of Stalling after Mismatches on the Error Catastrophe in Nonenzymatic Nucleic Acid Replication von Rajamani, Sudha, Ichida, Justin K, Antal, Tibor, Treco, Douglas A, Leu, Kevin, Nowak, Martin A, Szostak, Jack W, Chen, Irene A

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Notch inhibition allows oncogene-independent generation of iPS cells von Ichida, Justin K, TCW, Julia, Williams, Luis A, Carter, Ava C, Shi, Yingxiao, Moura, Marcelo T, Ziller, Michael, Singh, Sean, Amabile, Giovanni, Bock, Christoph, Umezawa, Akihiro, Rubin, Lee L, Bradner, James E, Akutsu, Hidenori, Meissner, Alexander, Eggan, Kevin

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Engineering skeletal muscle tissues with advanced maturity improves synapse formation with human induced pluripotent stem cell-derived motor neurons von Santoso, Jeffrey W., Li, Xiling, Gupta, Divya, Suh, Gio C., Hendricks, Eric, Lin, Shaoyu, Perry, Sarah, Ichida, Justin K., Dickman, Dion, McCain, Megan L.

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Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons von Shi, Yingxiao, Hung, Shu-Ting, Rocha, Gabriel, Lin, Shaoyu, Linares, Gabriel R, Staats, Kim A, Seah, Carina, Wang, Yaoming, Chickering, Michael, Lai, Jesse, Sugawara, Tohru, Sagare, Abhay P, Zlokovic, Berislav V, Ichida, Justin K

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Probing disorders of the nervous system using reprogramming approaches von Ichida, Justin K, Kiskinis, Evangelos

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Nanog-Independent Reprogramming to iPSCs with Canonical Factors von Carter, Ava C., Davis-Dusenbery, Brandi N., Koszka, Kathryn, Ichida, Justin K., Eggan, Kevin

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Protocol for Differentiation of Human iPSCs into Pulmonary Neuroendocrine Cells von Hor, Pooja, Ichida, Justin K., Borok, Zea, Ryan, Amy L.

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New approaches for direct conversion of patient fibroblasts into neural cells von Gopalakrishnan, Suhasni, Hor, Pooja, Ichida, Justin K

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Directly Reprogrammed Neurons Still Have Some Growing Up to Do von Li, Yichen, Ichida, Justin K.

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