The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans von Andreux, Pénélope A., Blanco-Bose, William, Ryu, Dongryeol, Burdet, Frédéric, Ibberson, Mark, Aebischer, Patrick, Auwerx, Johan, Singh, Anurag, Rinsch, Chris

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Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans von Wigger, Leonore, Cruciani-Guglielmacci, Céline, Nicolas, Anthony, Denom, Jessica, Fernandez, Neïké, Fumeron, Frédéric, Marques-Vidal, Pedro, Ktorza, Alain, Kramer, Werner, Schulte, Anke, Le Stunff, Hervé, Liechti, Robin, Xenarios, Ioannis, Vollenweider, Peter, Waeber, Gérard, Uphues, Ingo, Roussel, Ronan, Magnan, Christophe, Ibberson, Mark, Thorens, Bernard

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Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock von Bignon, Yohan, Wigger, Leonore, Ansermet, Camille, Weger, Benjamin D, Lagarrigue, Sylviane, Centeno, Gabriel, Durussel, Fanny, Götz, Lou, Ibberson, Mark, Pradervand, Sylvain, Quadroni, Manfredo, Weger, Meltem, Amati, Francesca, Gachon, Frédéric, Firsov, Dmitri

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Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes von Marselli, Lorella, Piron, Anthony, Suleiman, Mara, Colli, Maikel L., Yi, Xiaoyan, Khamis, Amna, Carrat, Gaelle R., Rutter, Guy A., Bugliani, Marco, Giusti, Laura, Ronci, Maurizio, Ibberson, Mark, Turatsinze, Jean-Valery, Boggi, Ugo, De Simone, Paolo, De Tata, Vincenzo, Lopes, Miguel, Nasteska, Daniela, De Luca, Carmela, Tesi, Marta, Bosi, Emanuele, Singh, Pratibha, Campani, Daniela, Schulte, Anke M., Solimena, Michele, Hecht, Peter, Rady, Brian, Bakaj, Ivona, Pocai, Alessandro, Norquay, Lisa, Thorens, Bernard, Canouil, Mickaël, Froguel, Philippe, Eizirik, Decio L., Cnop, Miriam, Marchetti, Piero

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Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity von Rodius, Sophie, de Klein, Niek, Jeanty, Céline, Sánchez-Iranzo, Héctor, Crespo, Isaac, Ibberson, Mark, Xenarios, Ioannis, Dittmar, Gunnar, Mercader, Nadia, Niclou, Simone P., Azuaje, Francisco

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Deciphering the Dynamic Transcriptional and Post-transcriptional Networks of Macrophages in the Healthy Heart and after Myocardial Injury von Walter, Wencke, Alonso-Herranz, Laura, Trappetti, Verdiana, Crespo, Isaac, Ibberson, Mark, Cedenilla, Marta, Karaszewska, Anna, Núñez, Vanessa, Xenarios, Ioannis, Arroyo, Alicia G., Sánchez-Cabo, Fátima, Ricote, Mercedes

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A systems genetics resource and analysis of sleep regulation in the mouse von Diessler, Shanaz, Jan, Maxime, Emmenegger, Yann, Guex, Nicolas, Middleton, Benita, Skene, Debra J, Ibberson, Mark, Burdet, Frederic, Götz, Lou, Pagni, Marco, Sankar, Martial, Liechti, Robin, Hor, Charlotte N, Xenarios, Ioannis, Franken, Paul

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A transcribed enhancer dictates mesendoderm specification in pluripotency von Alexanian, Michael, Maric, Daniel, Jenkinson, Stephen P., Mina, Marco, Friedman, Clayton E., Ting, Ching-Chia, Micheletti, Rudi, Plaisance, Isabelle, Nemir, Mohamed, Maison, Damien, Kernen, Jasmin, Pezzuto, Iole, Villeneuve, Dominic, Burdet, Frédéric, Ibberson, Mark, Leib, Stephen L., Palpant, Nathan J., Hernandez, Nouria, Ounzain, Samir, Pedrazzini, Thierry

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Protective role of the ELOVL2/docosahexaenoic acid axis in glucolipotoxicity-induced apoptosis in rodent beta cells and human islets von Bellini, Lara, Campana, Mélanie, Rouch, Claude, Chacinska, Marta, Bugliani, Marco, Meneyrol, Kelly, Hainault, Isabelle, Lenoir, Véronique, Denom, Jessica, Véret, Julien, Kassis, Nadim, Thorens, Bernard, Ibberson, Mark, Marchetti, Piero, Blachnio-Zabielska, Agnieszka, Cruciani-Guglielmacci, Céline, Prip-Buus, Carina, Magnan, Christophe, Le Stunff, Hervé

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Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes von Wigger, Leonore, Barovic, Marko, Brunner, Andreas-David, Marzetta, Flavia, Schöniger, Eyke, Mehl, Florence, Kipke, Nicole, Friedland, Daniela, Burdet, Frederic, Kessler, Camille, Lesche, Mathias, Thorens, Bernard, Bonifacio, Ezio, Legido-Quigley, Cristina, Barbier Saint Hilaire, Pierre, Delerive, Philippe, Dahl, Andreas, Klose, Christian, Gerl, Mathias J., Simons, Kai, Aust, Daniela, Weitz, Jürgen, Distler, Marius, Schulte, Anke M., Mann, Matthias, Ibberson, Mark, Solimena, Michele

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BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus von Lundgaard, Agnete T, Burdet, Frédéric, Siggaard, Troels, Westergaard, David, Vagiaki, Danai, Cantwell, Lisa, Röder, Timo, Vistisen, Dorte, Sparsø, Thomas, Giordano, Giuseppe N, Ibberson, Mark, Banasik, Karina, Brunak, Søren

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Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease von Lay, Abigail C., Tran, Van Du T., Nair, Viji, Betin, Virginie, Hurcombe, Jennifer A., Barrington, Alexandra F., Pope, Robert JP, Burdet, Frédéric, Mehl, Florence, Kryvokhyzha, Dmytro, Ahmad, Abrar, Sinton, Matthew C., Lewis, Philip, Wilson, Marieangela C., Menon, Rajasree, Otto, Edgar, Heesom, Kate J., Ibberson, Mark, Looker, Helen C., Nelson, Robert G., Ju, Wenjun, Kretzler, Matthias, Satchell, Simon C., Gomez, Maria F., Coward, Richard J. M.

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GLUT2 is a high affinity glucosamine transporter von Uldry, Marc, Ibberson, Mark, Hosokawa, Masaya, Thorens, Bernard

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Examining immune-inflammatory mechanisms of probiotic supplementation in depression: secondary findings from a randomized clinical trial von Sempach, Lukas, Doll, Jessica P. K., Limbach, Verena, Marzetta, Flavia, Schaub, Anna-Chiara, Schneider, Else, Kettelhack, Cedric, Mählmann, Laura, Schweinfurth-Keck, Nina, Ibberson, Mark, Lang, Undine E., Schmidt, André

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Endogenous RNAs Modulate MicroRNA Sorting to Exosomes and Transfer to Acceptor Cells von Squadrito, Mario Leonardo, Baer, Caroline, Burdet, Frédéric, Maderna, Claudio, Gilfillan, Gregor D., Lyle, Robert, Ibberson, Mark, De Palma, Michele

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Klf6 protects β-cells against insulin resistance-induced dedifferentiation von Dumayne, Christopher, Tarussio, David, Sanchez-Archidona, Ana Rodriguez, Picard, Alexandre, Basco, Davide, Berney, Xavier Pascal, Ibberson, Mark, Thorens, Bernard

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Biological Characterization of Gene Response to Insulin-Induced Hypoglycemia in Mouse Retina von Emery, Martine, Nanchen, Natacha, Preitner, Frédéric, Ibberson, Mark, Roduit, Raphaël

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Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes von Motterle, Anna, Gattesco, Sonia, Peyot, Marie-Line, Esguerra, Jonathan Lou S., Gomez-Ruiz, Ana, Laybutt, D. Ross, Gilon, Patrick, Burdet, Frédéric, Ibberson, Mark, Eliasson, Lena, Prentki, Marc, Regazzi, Romano

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Plasma triacylglycerols are biomarkers of β-cell function in mice and humans von Sánchez-Archidona, Ana Rodríguez, Cruciani-Guglielmacci, Céline, Roujeau, Clara, Wigger, Leonore, Lallement, Justine, Denom, Jessica, Barovic, Marko, Kassis, Nadim, Mehl, Florence, Weitz, Jurgen, Distler, Marius, Klose, Christian, Simons, Kai, Ibberson, Mark, Solimena, Michele, Magnan, Christophe, Thorens, Bernard

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A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion von Picard, Alexandre, Soyer, Josselin, Berney, Xavier, Tarussio, David, Quenneville, Simon, Jan, Maxime, Grouzmann, Eric, Burdet, Frédéric, Ibberson, Mark, Thorens, Bernard

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