Bioluminescent Reporters for Rapid Mechanism of Action Assessment in Tuberculosis Drug Discovery von Naran, Krupa, Moosa, Atica, Barry, 3rd, Clifton E, Boshoff, Helena I M, Mizrahi, Valerie, Warner, Digby F

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Environmental fungi target thiol homeostasis to compete with Mycobacterium tuberculosis von Malhotra, Neha, Oh, Sangmi, Finin, Peter, Medrano, Jessica, Andrews, Jenna, Goodwin, Michael, Markowitz, Tovah E, Lack, Justin, Boshoff, Helena I M, Barry, 3rd, Clifton Earl

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Meropenem-Clavulanic Acid Shows Activity against Mycobacterium tuberculosis In Vivo von ENGLAND, Kathleen, BOSHOFF, Helena I. M, ARORA, Kriti, WEINER, Danielle, DAYAO, Emmanuel, SCHIMEL, Daniel, VIA, Laura E, BARRY, Clifton E

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PA-824 Kills Nonreplicating Mycobacterium tuberculosis by Intracellular NO Release von Singh, Ramandeep, Manjunatha, Ujjini, Boshoff, Helena I.M, Ha, Young Hwan, Niyomrattanakit, Pornwaratt, Ledwidge, Richard, Dowd, Cynthia S, Lee, Ill Young, Kim, Pilho, Zhang, Liang, Kang, Sunhee, Keller, Thomas H, Jiricek, Jan, Barry, Clifton E. 3rd

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Mutations in gidB Confer Low-Level Streptomycin Resistance in Mycobacterium tuberculosis von WONG, Sharon Y, JONG SEOK LEE, HYUN KYUNG KWAK, VIA, Laura E, BOSHOFF, Helena I. M, BARRY, Clifton E

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Development of Inhibitors against Mycobacterium abscessus tRNA (m1G37) Methyltransferase (TrmD) Using Fragment-Based Approaches von Whitehouse, Andrew J, Thomas, Sherine E, Brown, Karen P, Fanourakis, Alexander, Chan, Daniel S.-H, Libardo, M. Daben J, Mendes, Vitor, Boshoff, Helena I. M, Floto, R. Andres, Abell, Chris, Blundell, Tom L, Coyne, Anthony G

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The Three RelE Homologs of Mycobacterium tuberculosis Have Individual, Drug-Specific Effects on Bacterial Antibiotic Tolerance von SINGH, Ramandeep, BARRY, Clifton E, BOSHOFF, Helena I. M

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Proteasomal Protein Degradation in Mycobacteria Is Dependent upon a Prokaryotic Ubiquitin-like Protein von Burns, Kristin E., Liu, Wei-Ting, Boshoff, Helena I.M., Dorrestein, Pieter C., Barry, Clifton E.

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1-(1-Arylethylpiperidin-4-yl)thymine Analogs as Antimycobacterial TMPK Inhibitors von Jian, Yanlin, Hulpia, Fabian, D P Risseeuw, Martijn, Forbes, He Eun, Caljon, Guy, Munier-Lehmann, Hélène, I M Boshoff, Helena, Van Calenbergh, Serge

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Validation of CoaBC as a Bactericidal Target in the Coenzyme A Pathway of Mycobacterium tuberculosis von Evans, Joanna C, Trujillo, Carolina, Wang, Zhe, Eoh, Hyungjin, Ehrt, Sabine, Schnappinger, Dirk, Boshoff, Helena I. M, Rhee, Kyu Y, Barry, Clifton E, Mizrahi, Valerie

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Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis von Ioerger, Thomas R, O'Malley, Theresa, Liao, Reiling, Guinn, Kristine M, Hickey, Mark J, Mohaideen, Nilofar, Murphy, Kenan C, Boshoff, Helena I M, Mizrahi, Valerie, Rubin, Eric J, Sassetti, Christopher M, Barry, 3rd, Clifton E, Sherman, David R, Parish, Tanya, Sacchettini, James C

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Susceptibility of Mycobacterium tuberculosis Cytochrome bd Oxidase Mutants to Compounds Targeting the Terminal Respiratory Oxidase, Cytochrome c von Moosa, Atica, Lamprecht, Dirk A, Arora, Kriti, Barry, 3rd, Clifton E, Boshoff, Helena I M, Ioerger, Thomas R, Steyn, Adrie J C, Mizrahi, Valerie, Warner, Digby F

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Structure–Activity Relationships of Pyrazolo[1,5‑a]pyrimidin-7(4H)‑ones as Antitubercular Agents von Oh, Sangmi, Libardo, M. Daben J, Azeeza, Shaik, Pauly, Gary T, Roma, Jose Santinni O, Sajid, Andaleeb, Tateishi, Yoshitaka, Duncombe, Caroline, Goodwin, Michael, Ioerger, Thomas R, Wyatt, Paul G, Ray, Peter C, Gray, David W, Boshoff, Helena I. M, Barry, Clifton E

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Editorial: Drug-resistant Mycobacterium tuberculosis von Boshoff, Helena I M, Warner, Digby F, Gold, Ben

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Meropenem inhibits D,D-carboxypeptidase activity in Mycobacterium tuberculosis von Kumar, Pradeep, Arora, Kriti, Lloyd, John R., Lee, Ill Y., Nair, Vinod, Fischer, Elizabeth, Boshoff, Helena I. M., Barry III, Clifton E.

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Expanding Benzoxazole-Based Inosine 5′-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure–Activity As Potential Antituberculosis Agents von Chacko, Shibin, Boshoff, Helena I. M, Singh, Vinayak, Ferraris, Davide M, Gollapalli, Deviprasad R, Zhang, Minjia, Lawson, Ann P, Pepi, Michael J, Joachimiak, Andrzej, Rizzi, Menico, Mizrahi, Valerie, Cuny, Gregory D, Hedstrom, Lizbeth

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Tuberculosis — metabolism and respiration in the absence of growth von Boshoff, Helena I. M., Barry, Clifton E.

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Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents von Jian, Yanlin, Merceron, Romain, De Munck, Steven, Forbes, He Eun, Hulpia, Fabian, Risseeuw, Martijn D.P., Van Hecke, Kristof, Savvides, Savvas N., Munier-Lehmann, Hélène, Boshoff, Helena.I.M., Van Calenbergh, Serge

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genetic strategy to identify targets for the development of drugs that prevent bacterial persistence von Kim, Jee-Hyun, O'Brien, Kathryn M., Sharma, Ritu, Boshoff, Helena I. M., Rehren, German, Chakraborty, Sumit, Wallach, Joshua B., Monteleone, Mercedes, Wilson, Daniel J., Aldrich, Courtney C., Barry, Clifton E., Rhee, Kyu Y., Ehrt, Sabine, Schnappinger, Dirk

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Discovery and Structure–Activity-Relationship Study of N‑Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β‑d‑ribose 2′-Oxidas... von Oh, Sangmi, Park, Yumi, Engelhart, Curtis A, Wallach, Joshua B, Schnappinger, Dirk, Arora, Kriti, Manikkam, Michelle, Gac, Brian, Wang, Hongwu, Murgolo, Nicholas, Olsen, David B, Goodwin, Michael, Sutphin, Michelle, Weiner, Danielle M, Via, Laura E, Boshoff, Helena I. M, Barry, Clifton E

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