Micro-foundations of dynamic capabilities to facilitate university technology transfer von Ma, Zhongxuan, Augustijn, K D, De Esch, I J P, Bossink, B A G

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Pharmacological characterization of a small‐molecule agonist for the chemokine receptor CXCR3 von Scholten, DJ, Canals, M, Wijtmans, M, de Munnik, S, Nguyen, P, Verzijl, D, de Esch, IJP, Vischer, HF, Smit, MJ, Leurs, R

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KLIFS: A Knowledge-Based Structural Database To Navigate Kinase–Ligand Interaction Space von van Linden, Oscar P. J., Kooistra, Albert J., Leurs, Rob, de Esch, Iwan J. P., de Graaf, Chris

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A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design von Kooistra, A J, Kuhne, S, Esch, I J P, Leurs, R, Graaf, C

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KLIFS: a structural kinase-ligand interaction database von Kooistra, Albert J, Kanev, Georgi K, van Linden, Oscar P J, Leurs, Rob, de Esch, Iwan J P, de Graaf, Chris

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Micro-foundations of dynamic capabilities to facilitate university technology transfer von Zhongxuan Ma, K D Augustijn, I J P De Esch, B A G Bossink

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The histamine H3 receptor: from gene cloning to H3 receptor drugs von Leurs, Rob, Bakker, Remko A., Timmerman, Henk, de Esch, Iwan J. P.

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Fragment-to-Lead Medicinal Chemistry Publications in 2020 von de Esch, Iwan J. P, Erlanson, Daniel A, Jahnke, Wolfgang, Johnson, Christopher N, Walsh, Louise

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Aminergic GPCR–Ligand Interactions: A Chemical and Structural Map of Receptor Mutation Data von Vass, Márton, Podlewska, Sabina, de Esch, Iwan J. P, Bojarski, Andrzej J, Leurs, Rob, Kooistra, Albert J, de Graaf, Chris

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PDEStrIAn: A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design von Jansen, Chimed, Kooistra, Albert J, Kanev, Georgi K, Leurs, Rob, de Esch, Iwan J. P, de Graaf, Chris

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Structure-based exploration and pharmacological evaluation of N-substituted piperidin-4-yl-methanamine CXCR4 chemokine receptor antagonists von Adlere, I., Sun, S., Zarca, A., Roumen, L., Gozelle, M., Viciano, C. Perpiñá, Caspar, B., Arimont, M., Bebelman, J.P., Briddon, S.J., Hoffmann, C., Hill, S.J., Smit, M.J., Vischer, H.F., Wijtmans, M., de Graaf, C., de Esch, I.J.P., Leurs, R.

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Fragment-to-Lead Medicinal Chemistry Publications in 2021 von Walsh, Louise, Erlanson, Daniel A., de Esch, Iwan J. P., Jahnke, Wolfgang, Woodhead, Andrew, Wren, Ella

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Fragment-to-Lead Medicinal Chemistry Publications in 2022 von Woodhead, Andrew J., Erlanson, Daniel A., de Esch, Iwan J. P., Holvey, Rhian S., Jahnke, Wolfgang, Pathuri, Puja

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Structure-Based Prediction of G‑Protein-Coupled Receptor Ligand Function: A β‑Adrenoceptor Case Study von Kooistra, Albert J, Leurs, Rob, de Esch, Iwan J. P, de Graaf, Chris

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Puckering the Planar Landscape of Fragments: Design and Synthesis of a 3D Cyclobutane Fragment Library von Hamilton, David J., Beemsterboer, Marieke, Carter, Caroline M., Elsayed, Jasmina, Huiberts, Rilana E. M., Klein, Hanna F., O'Brien, Peter, Esch, Iwan J. P., Wijtmans, Maikel

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A fluorescent approach for identifying P2X1 ligands von Ruepp, Marc-David, Brozik, James A., de Esch, Iwan J.P., Farndale, Richard W., Murrell-Lagnado, Ruth D., Thompson, Andrew J.

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Escape from planarity in fragment-based drug discovery: A synthetic strategy analysis of synthetic 3D fragment libraries von Klein, Hanna F., Hamilton, David J., de Esch, Iwan J.P., Wijtmans, Maikel, O'Brien, Peter

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A Structural Framework for GPCR Chemogenomics: What’s In a Residue Number? von Vass, Márton, Kooistra, Albert J., Verhoeven, Stefan, Gloriam, David, de Esch, Iwan J. P., de Graaf, Chris

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3D‐e‐Chem: Structural Cheminformatics Workflows for Computer‐Aided Drug Discovery von Kooistra, Albert J., Vass, Márton, McGuire, Ross, Leurs, Rob, de Esch, Iwan J. P., Vriend, Gert, Verhoeven, Stefan, de Graaf, Chris

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Photoswitching the Efficacy of a Small‐Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism von Gómez‐Santacana, Xavier, de Munnik, Sabrina M., Vijayachandran, Prashanna, Da Costa Pereira, Daniel, Bebelman, Jan Paul M., de Esch, Iwan J. P., Vischer, Henry F., Wijtmans, Maikel, Leurs, Rob

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