Different Electrostatic Potentials Define ETGE and DLG Motifs as Hinge and Latch in Oxidative Stress Response von Tong, Kit I., Padmanabhan, Balasundaram, Kobayashi, Akira, Shang, Chengwei, Hirotsu, Yosuke, Yokoyama, Shigeyuki, Yamamoto, Masayuki

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Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development von Kawazu, Masahito, Saso, Kayoko, Tong, Kit I, McQuire, Tracy, Goto, Kouichiro, Son, Dong-Ok, Wakeham, Andrew, Miyagishi, Makoto, Mak, Tak W, Okada, Hitoshi

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Molecular mechanism activating nrf2–keap1 pathway in regulation of adaptive response to electrophiles von Itoh, Ken, Tong, Kit I, Yamamoto, Masayuki

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The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 von Sakamoto, Ayako, Tong, Kit I, Kim, Mihee, Tanaka, Keiji, Sou, Yu-Shin, Taguchi, Keiko, Kominami, Eiki, Nishito, Yasumasa, Ichimura, Yoshinobu, Ueno, Izumi, Waguri, Satoshi, Ueno, Takashi, Motohashi, Hozumi, Komatsu, Masaaki, Yamamoto, Masayuki, Kurokawa, Hirofumi, Iemura, Shun-ichiro, Natsume, Tohru, Kobayashi, Akira

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Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes von Zamudio, Alicia V., Dall’Agnese, Alessandra, Henninger, Jonathan E., Manteiga, John C., Afeyan, Lena K., Hannett, Nancy M., Coffey, Eliot L., Li, Charles H., Oksuz, Ozgur, Sabari, Benjamin R., Boija, Ann, Klein, Isaac A., Hawken, Susana W., Spille, Jan-Hendrik, Decker, Tim-Michael, Cisse, Ibrahim I., Abraham, Brian J., Lee, Tong I., Taatjes, Dylan J., Schuijers, Jurian, Young, Richard A.

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Transcription factors interact with RNA to regulate genes von Oksuz, Ozgur, Henninger, Jonathan E., Warneford-Thomson, Robert, Zheng, Ming M., Erb, Hailey, Vancura, Adrienne, Overholt, Kalon J., Hawken, Susana Wilson, Banani, Salman F., Lauman, Richard, Reich, Lauren N., Robertson, Anne L., Hannett, Nancy M., Lee, Tong I., Zon, Leonard I., Bonasio, Roberto, Young, Richard A.

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Keap1 Recruits Neh2 through Binding to ETGE and DLG Motifs: Characterization of the Two-Site Molecular Recognition Model von Tong, Kit I., Katoh, Yasutake, Kusunoki, Hideki, Itoh, Ken, Tanaka, Toshiyuki, Yamamoto, Masayuki

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Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy von Shibata, Tatsuhiro, Ohta, Tsutomu, Tong, Kit I, Kokubu, Akiko, Odogawa, Reiko, Tsuta, Koji, Asamura, Hisao, Yamamoto, Masayuki, Hirohashi, Setsuo

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Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keap1 von Kobayashi, Akira, Kang, Moon-Il, Watai, Yoriko, Tong, Kit I., Shibata, Takahiro, Uchida, Koji, Yamamoto, Masayuki

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Structural Basis for Defects of Keap1 Activity Provoked by Its Point Mutations in Lung Cancer von Padmanabhan, Balasundaram, Tong, Kit I., Ohta, Tsutomu, Nakamura, Yoshihiro, Scharlock, Maria, Ohtsuji, Makiko, Kang, Moon-Il, Kobayashi, Akira, Yokoyama, Shigeyuki, Yamamoto, Masayuki

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Association of C-reactive protein with future development of diabetes: a population-based 7-year cohort study among Norwegian adults aged 30 and older in the Tromsø Study 2007–2016... von Tong, Kit I, Hopstock, Laila Arnesdatter, Cook, Sarah

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Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats von ElZohary, Lama, Weglicki, William B, Chmielinska, Joanna J, Kramer, Jay H, Mak, I Tong

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Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism von Tong, Kit I., Kobayashi, Akira, Katsuoka, Fumiki, Yamamoto, Masayuki

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New approaches for enhanced detection of enteroviruses from Hawaiian environmental waters von Connell, Christina, Tong, Hsin-I, Wang, Zi, Allmann, Erin, Lu, Yuanan

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The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance von Dall’Agnese, Alessandra, Platt, Jesse M., Zheng, Ming M., Friesen, Max, Dall’Agnese, Giuseppe, Blaise, Alyssa M., Spinelli, Jessica B., Henninger, Jonathan E., Tevonian, Erin N., Hannett, Nancy M., Lazaris, Charalampos, Drescher, Hannah K., Bartsch, Lea M., Kilgore, Henry R., Jaenisch, Rudolf, Griffith, Linda G., Cisse, Ibrahim I., Jeppesen, Jacob F., Lee, Tong I., Young, Richard A.

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Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains von Ogura, Toshihiko, Tong, Kit I, Mio, Kazuhiro, Maruyama, Yuusuke, Kurokawa, Hirofumi, Sato, Chikara, Yamamoto, Masayuki

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Substance P receptor blocker, aprepitant, inhibited cutaneous and other neurogenic inflammation side effects of the EGFR1-TKI, erlotinib von Chmielinska, Joanna J., Kramer, Jay H., Mak, I-Tong, Spurney, Christopher F., Weglicki, William B.

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Perceptions and Uses of Public Open Spaces During the Covid-19 Pandemic: Prevention Measures as Endangering Possibilities of Active Ageing von Ye, Xi, Chen, Ke, Chen, Jinxuan, Chan, I-Tong

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Complete genome assembly of Hawai’i environmental nontuberculous mycobacteria reveals unexpected co-isolation with methylobacteria von Hendrix, Jo, Epperson, L. Elaine, Tong, Eric I, Chan, Yvonne L, Hasan, Nabeeh A, Dawrs, Stephanie N, Norton, Grant J, Virdi, Ravleen, Crooks, James L, Chan, Edward D, Honda, Jennifer R, Strong, Michael

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Electrophilic Nitro-fatty Acids Activate NRF2 by a KEAP1 Cysteine 151-independent Mechanism von Kansanen, Emilia, Bonacci, Gustavo, Schopfer, Francisco J., Kuosmanen, Suvi M., Tong, Kit I., Leinonen, Hanna, Woodcock, Steven R., Yamamoto, Masayuki, Carlberg, Carsten, Ylä-Herttuala, Seppo, Freeman, Bruce A., Levonen, Anna-Liisa

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