Abstract 3347: Characterization of gut microbiota and identification of key bacterial species associated with immune response using a new Ion Torrent next-generation sequencing ass... von Sarda, Shrutii, Merrill, David C., Shin, Heesun, McGeachy, Anna, Drews, Birgit, Lee, Wing, Gottimukkala, Rajesh Kumar, Au-Young, Janice, Hyland, Fiona M.

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Analytical Validation of a Next-Generation Sequencing Assay to Monitor Immune Responses in Solid Tumors von Conroy, Jeffrey M., Pabla, Sarabjot, Glenn, Sean T., Burgher, Blake, Nesline, Mary, Papanicolau-Sengos, Antonios, Andreas, Jonathan, Giamo, Vincent, Lenzo, Felicia L., Hyland, Fiona C.L., Omilian, Angela, Bshara, Wiam, Qin, Moachun, He, Ji, Puzanov, Igor, Ernstoff, Marc S., Gardner, Mark, Galluzzi, Lorenzo, Morrison, Carl

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A second-generation combined linkage physical map of the human genome von Matise, Tara C, Chen, Fang, Chen, Wenwei, De La Vega, Francisco M, Hansen, Mark, He, Chunsheng, Hyland, Fiona C L, Kennedy, Giulia C, Kong, Xiangyang, Murray, Sarah S, Ziegle, Janet S, Stewart, William C L, Buyske, Steven

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Good laboratory practice for clinical next-generation sequencing informatics pipelines von Gargis, Amy S, Kalman, Lisa, Bick, David P, da Silva, Cristina, Dimmock, David P, Funke, Birgit H, Gowrisankar, Sivakumar, Hegde, Madhuri R, Kulkarni, Shashikant, Mason, Christopher E, Nagarajan, Rakesh, Voelkerding, Karl V, Worthey, Elizabeth A, Aziz, Nazneen, Barnes, John, Bennett, Sarah F, Bisht, Himani, Church, Deanna M, Dimitrova, Zoya, Gargis, Shaw R, Hafez, Nabil, Hambuch, Tina, Hyland, Fiona C L, Luna, Ruth Ann, MacCannell, Duncan, Mann, Tobias, McCluskey, Megan R, McDaniel, Timothy K, Ganova-Raeva, Lilia M, Rehm, Heidi L, Reid, Jeffrey, Campo, David S, Resnick, Richard B, Ridge, Perry G, Salit, Marc L, Skums, Pavel, Wong, Lee-Jun C, Zehnbauer, Barbara A, Zook, Justin M, Lubin, Ira M

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Extensive sequencing of seven human genomes to characterize benchmark reference materials von Zook, Justin M., Catoe, David, McDaniel, Jennifer, Vang, Lindsay, Spies, Noah, Sidow, Arend, Weng, Ziming, Liu, Yuling, Mason, Christopher E., Alexander, Noah, Henaff, Elizabeth, McIntyre, Alexa B.R., Chandramohan, Dhruva, Chen, Feng, Jaeger, Erich, Moshrefi, Ali, Pham, Khoa, Stedman, William, Liang, Tiffany, Saghbini, Michael, Dzakula, Zeljko, Hastie, Alex, Cao, Han, Deikus, Gintaras, Schadt, Eric, Sebra, Robert, Bashir, Ali, Truty, Rebecca M., Chang, Christopher C., Gulbahce, Natali, Zhao, Keyan, Ghosh, Srinka, Hyland, Fiona, Fu, Yutao, Chaisson, Mark, Xiao, Chunlin, Trow, Jonathan, Sherry, Stephen T., Zaranek, Alexander W., Ball, Madeleine, Bobe, Jason, Estep, Preston, Church, George M., Marks, Patrick, Kyriazopoulou-Panagiotopoulou, Sofia, Zheng, Grace X.Y., Schnall-Levin, Michael, Ordonez, Heather S., Mudivarti, Patrice A., Giorda, Kristina, Sheng, Ying, Rypdal, Karoline Bjarnesdatter, Salit, Marc

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Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors von Hovelson, Daniel H, McDaniel, Andrew S, Cani, Andi K, Johnson, Bryan, Rhodes, Kate, Williams, Paul D, Bandla, Santhoshi, Bien, Geoffrey, Choppa, Paul, Hyland, Fiona, Gottimukkala, Rajesh, Liu, Guoying, Manivannan, Manimozhi, Schageman, Jeoffrey, Ballesteros-Villagrana, Efren, Grasso, Catherine S, Quist, Michael J, Yadati, Venkata, Amin, Anmol, Siddiqui, Javed, Betz, Bryan L, Knudsen, Karen E, Cooney, Kathleen A, Feng, Felix Y, Roh, Michael H, Nelson, Peter S, Liu, Chia-Jen, Beer, David G, Wyngaard, Peter, Chinnaiyan, Arul M, Sadis, Seth, Rhodes, Daniel R, Tomlins, Scott A

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Large scale real-time PCR validation on gene expression measurements from two commercial long-oligonucleotide microarrays von Wang, Yulei, Barbacioru, Catalin, Hyland, Fiona, Xiao, Wenming, Hunkapiller, Kathryn L, Blake, Julie, Chan, Frances, Gonzalez, Carolyn, Zhang, Lu, Samaha, Raymond R

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Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding von McKernan, Kevin Judd, Peckham, Heather E, Costa, Gina L, McLaughlin, Stephen F, Fu, Yutao, Tsung, Eric F, Clouser, Christopher R, Duncan, Cisyla, Ichikawa, Jeffrey K, Lee, Clarence C, Zhang, Zheng, Ranade, Swati S, Dimalanta, Eileen T, Hyland, Fiona C, Sokolsky, Tanya D, Zhang, Lei, Sheridan, Andrew, Fu, Haoning, Hendrickson, Cynthia L, Li, Bin, Kotler, Lev, Stuart, Jeremy R, Malek, Joel A, Manning, Jonathan M, Antipova, Alena A, Perez, Damon S, Moore, Michael P, Hayashibara, Kathleen C, Lyons, Michael R, Beaudoin, Robert E, Coleman, Brittany E, Laptewicz, Michael W, Sannicandro, Adam E, Rhodes, Michael D, Gottimukkala, Rajesh K, Yang, Shan, Bafna, Vineet, Bashir, Ali, MacBride, Andrew, Alkan, Can, Kidd, Jeffrey M, Eichler, Evan E, Reese, Martin G, De La Vega, Francisco M, Blanchard, Alan P

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A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structu... von McEvoy, Natalie L, Clarke, Jennifer L, Mc Elvaney, Oliver J, Mc Elvaney, Oisin F, Boland, Fiona, Hyland, Deirdre, Geoghegan, Pierce, Donnelly, Karen, Friel, Oisin, Cullen, Ailbhe, Collins, Ann M, Fraughen, Daniel, Martin-Loeches, Ignacio, Hennessy, Martina, Laffey, John G, Mc Elvaney, Noel G, Curley, Gerard F

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Abstract 177: RNA sequencing based gene fusion detection with oncomine comprehensive assay plus von Marcovitz, Amir, Gottimukkala, Rajesh K., Bee, Gary G., Kilzer, Jennifer M., Mital, Vinay K., Wong-Ho, Elain, Yang, Chenchen, Tseng, Yu-Ting, Myrand, Scott P., Williams, Paul D., Sadis, Seth, Hyland, Fiona C.

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CT-derived measures of muscle quantity and quality predict poorer outcomes from elective colorectal surgery: a UK multicentre retrospective cohort study von Blackwell, J. E. M., Herrod, P. J. J., Doleman, B., Boyd-Carson, H., Dolan, D., Wheldon, L., Brown, S. R., Banerjea, A., Moug, S., Lund, J. N.

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Long-amplicon TCRβ repertoire sequencing to reveal human T-cell receptor variable gene polymorphism: Implications for the prediction and interpretation of immunotherapy outcome von Looney, Timothy, Glavin, Alexander, Pabla, Sarabjot, Glenn, Sean T., Miller, Lauren, Topacio-Hall, Denise, Linch, Elizabeth, Pankov, Aleksandr, Zheng, Jianping, Conroy, Jeffrey M., Morrison, Carl, Lowman, Geoffrey, Andersen, Mark, Hyland, Fiona

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Principles and Recommendations for Standardizing the Use of the Next-Generation Sequencing Variant File in Clinical Settings von Lubin, Ira M, Aziz, Nazneen, Babb, Lawrence J, Ballinger, Dennis, Bisht, Himani, Church, Deanna M, Cordes, Shaun, Eilbeck, Karen, Hyland, Fiona, Kalman, Lisa, Landrum, Melissa, Lockhart, Edward R, Maglott, Donna, Marth, Gabor, Pfeifer, John D, Rehm, Heidi L, Roy, Somak, Tezak, Zivana, Truty, Rebecca, Ullman-Cullere, Mollie, Voelkerding, Karl V, Worthey, Elizabeth A, Zaranek, Alexander W, Zook, Justin M

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A randomized, double-blind, placebo-controlled trial of intravenous alpha-1 antitrypsin for ARDS secondary to COVID-19 von McElvaney, Oliver J., McEvoy, Natalie L., Boland, Fiona, McElvaney, Oisín F., Hogan, Grace, Donnelly, Karen, Friel, Oisín, Browne, Emmet, Fraughen, Daniel D., Murphy, Mark P., Clarke, Jennifer, Choileáin, Orna Ní, O’Connor, Eoin, McGuinness, Rory, Boylan, Maria, Kelly, Alan, Hayden, John C., Collins, Ann M., Cullen, Ailbhe, Hyland, Deirdre, Carroll, Tomás P., Geoghegan, Pierce, Laffey, John G., Hennessy, Martina, Martin-Loeches, Ignacio, McElvaney, Noel G., Curley, Gerard F.

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Patterns of Linkage Disequilibrium between SNPs in a Sardinian Population Isolate and the Selection of Markers for Association Studies von Angius, Andrea, Hyland, Fiona C. L., Persico, Ivana, Pirastu, Nicola, Woodage, Trevor, Pirastu, Mario, De La Vega, Francisco M.

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The Oncomine Cancer Research Panel, a scalable next-generation sequencing system for relevant somatic variant assessment in solid tumors von Hovelson, Daniel H., Cani, Andi K., McDaniel, Andrew, Johnson, Bryan, Rhodes, Kate, Williams, Paul D, Bandla, Santhoshi, Choppa, Paul, Hyland, Fiona, Liu, Guoying, Schageman, Jeoffrey, Yadati, Venkata, Amin, Anmol, Cooney, Kathleen A., Feng, Felix Yi-Chung, Liu, Chia-Jen, Chinnaiyan, Arul M., Sadis, Seth, Rhodes, Dan, Tomlins, Scott A.

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Development and Validation of a Scalable Next-Generation Sequencing System for Assessing Relevant Somatic Variants in Solid Tumors12 von Hovelson, Daniel H., McDaniel, Andrew S., Cani, Andi K., Johnson, Bryan, Rhodes, Kate, Williams, Paul D., Bandla, Santhoshi, Bien, Geoffrey, Choppa, Paul, Hyland, Fiona, Gottimukkala, Rajesh, Liu, Guoying, Manivannan, Manimozhi, Schageman, Jeoffrey, Ballesteros-Villagrana, Efren, Grasso, Catherine S., Quist, Michael J., Yadati, Venkata, Amin, Anmol, Siddiqui, Javed, Betz, Bryan L., Knudsen, Karen E., Cooney, Kathleen A., Feng, Felix Y., Roh, Michael H., Nelson, Peter S., Liu, Chia-Jen, Beer, David G., Wyngaard, Peter, Chinnaiyan, Arul M., Sadis, Seth, Rhodes, Daniel R., Tomlins, Scott A.

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Abstracts from the 4th ImmunoTherapy of Cancer Conference von Uher, O, Kopecký, J, Steele, K, Tan, T, Spitzmueller, A, Korn, R, X Li, Koeck, S, Lorenz, E, Zwierzina, H, Coosemans, A, Giovannoni, R, Radaelli, E, M Van Ranst, X Xu, Guo, S, Quandt, D, Deen, D, Hirn, A, Vokac, Y, Schmid, C, Vimeux, L, Peranzoni, E, Guilbert, T, Bercovici, N, Boeck, C L, Kugler, C, Schmetzer, H M, Markota, A, J Suárez Gosálvez, Endres, S, Klar, R, Jaschinski, F, Zelger, B, Öfner, D, Puerto-Aquino, A, Rumbo-Nava, U, A Van Hoylandt, Vergote, I, Budinska, E, Bencsikova, B, Hanakova, B, Zdrazilova-Dubska, L, Pankov, Alex, Looney, Tim, Mongan, Ann, Tan, J B L, Gonçalves, G, Pinto, M L, Athelogou, M, Sykora, J, Richards, D M, Pinho, M P, Johnson, C, Rees, R C, Rutella, S, Wang, S, Redondo-Müller, M, Heinonen, K, Marschall, V, Jin, Y, Zhai, G, Zhang, J, Kluger, H, Roder, J, Asmellash, S, Sullivan, R, Sutanto, W, Guenther, T, Salih, H, Borkhardt, A, Kim, Y, I Oh, Park, C, Song, S, Valik, D, Petrakova, K, Aguilar-Cazares, D, Camacho-Mendoza, C, Islas-Vazquez, L, Chavez-Dominguez, R, Yang, S, Moynihan, K D, Noh, M, Bekdemir, A, Wittig, B, Schmidt, M, McKee, D, Moss, R W, Gordon, E M, Sankhala, K K, M Cruz Rodríguez, Saliba, H, Otterhaug, T, Nedberg, A, Edwards, V, Selbo, P, Jaitly, T, Heise, C, Dorman, K

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A second-generation combined linkage–physical map of the human genome: Table 1 von Matise, Tara C., Chen, Fang, Chen, Wenwei, De La Vega, Francisco M., Hansen, Mark, He, Chunsheng, Hyland, Fiona C.L., Kennedy, Giulia C., Kong, Xiangyang, Murray, Sarah S., Ziegle, Janet S., Stewart, William C.L., Buyske, Steven

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Experiences and expectations of the new genetics in relation to familial risk of breast cancer: a comparison of the views of GPs and practice nurses von Walter, Fiona M, Kinmonth, Ann Louise, Hyland, Fawzia, Murrell, Paul, Marteau, Theresa M, Todd, Chris

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