High-throughput screening of the ReFRAME, Pandemic Box, and COVID Box drug repurposing libraries against SARS-CoV-2 nsp15 endoribonuclease to identify small-molecule inhibitors of... von Choi, Ryan, Zhou, Mowei, Shek, Roger, Wilson, Jesse W, Tillery, Logan, Craig, Justin K, Salukhe, Indraneel A, Hickson, Sarah E, Kumar, Neeraj, James, Rhema M, Buchko, Garry W, Wu, Ruilian, Huff, Sydney, Nguyen, Tu-Trinh, Hurst, Brett L, Cherry, Sara, Barrett, Lynn K, Hyde, Jennifer L, Van Voorhis, Wesley C

Volltext

Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylation von Hyde, Jennifer L, Diamond, Michael S

Volltext

Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome von Tsu, Brian V, Agarwal, Rimjhim, Gokhale, Nandan S, Kulsuptrakul, Jessie, Ryan, Andrew P, Fay, Elizabeth J, Castro, Lennice K, Beierschmitt, Christopher, Yap, Christina, Turcotte, Elizabeth A, Delgado-Rodriguez, Sofia E, Vance, Russell E, Hyde, Jennifer L, Savan, Ram, Mitchell, Patrick S, Daugherty, Matthew D

Volltext

The Norovirus NS3 Protein Is a Dynamic Lipid- and Microtubule-Associated Protein Involved in Viral RNA Replication von Cotton, Ben T, Hyde, Jennifer L, Sarvestani, Soroush T, Sosnovtsev, Stanislav V, Green, Kim Y, White, Peter A, Mackenzie, Jason M

Volltext

Mouse Norovirus 1 Utilizes the Cytoskeleton Network To Establish Localization of the Replication Complex Proximal to the Microtubule Organizing Center von HYDE, Jennifer L, GILLESPIE, Leah K, MACKENZIE, Jason M

Volltext

Mouse Norovirus Replication Is Associated with Virus-Induced Vesicle Clusters Originating from Membranes Derived from the Secretory Pathway von HYDE, Jennifer L, SOSNOVTSEV, Stanislav V, GREEN, Kim Y, WOBUS, Christiane, VIRGIN, Herbert W, MACKENZIE, Jason M

Volltext

RNA structures within Venezuelan equine encephalitis virus E1 alter macrophage replication fitness and contribute to viral emergence von Hickson, Sarah E, Hyde, Jennifer L

Volltext

The Interferon-Stimulated Gene IFITM3 Restricts Infection and Pathogenesis of Arthritogenic and Encephalitic Alphaviruses von Poddar, Subhajit, Hyde, Jennifer L, Gorman, Matthew J, Farzan, Michael, Diamond, Michael S

Volltext

RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions von Schwerk, Johannes, Soveg, Frank W., Ryan, Andrew P., Thomas, Kerri R., Hatfield, Lauren D., Ozarkar, Snehal, Forero, Adriana, Kell, Alison M., Roby, Justin A., So, Lomon, Hyde, Jennifer L., Gale, Michael, Daugherty, Matthew D., Savan, Ram

Volltext

A Viral RNA Structural Element Alters Host Recognition of Nonself RNA von Hyde, Jennifer L., Gardner, Christina L., Kimura, Taishi, White, James P., Liu, Gai, Trobaugh, Derek W., Huang, Cheng, Tonelli, Marco, Paessler, Slobodan, Takeda, Kiyoshi, Klimstra, William B., Amarasinghe, Gaya K., Diamond, Michael S.

Volltext

The 5′ and 3′ ends of alphavirus RNAs – Non-coding is not non-functional von Hyde, Jennifer L., Chen, Rubing, Trobaugh, Derek W., Diamond, Michael S., Weaver, Scott C., Klimstra, William B., Wilusz, Jeffrey

Volltext

Norovirus-mediated translation repression promotes macrophage cell death von Aktepe, Turgut E, Deerain, Joshua M, Hyde, Jennifer L, Fritzlar, Svenja, Mead, Eleanor M, Carrera Montoya, Julio, Hachani, Abderrahman, Pearson, Jaclyn S, White, Peter A, Mackenzie, Jason M

Volltext

Murine norovirus infection of macrophages induces intrinsic apoptosis as the major form of programmed cell death von Deerain, Joshua M., Aktepe, Turgut E., Trenerry, Alice M., Ebert, Gregor, Hyde, Jennifer L., Charry, Katelyn, Edgington-Mitchell, Laura, Xu, Banyan, Ambrose, Rebecca L., Sarvestani, Soroush T., Lawlor, Kate E., Pearson, Jaclyn S., White, Peter A., Mackenzie, Jason M.

Volltext

Developing a Prototype Pathogen Plan and Research Priorities for the Alphaviruses von Powers, Ann M, Williamson, Lauren E, Carnahan, Robert H, Crowe, James E, Hyde, Jennifer L, Jonsson, Colleen B, Nasar, Farooq, Weaver, Scott C

Volltext

Determinants of pegivirus persistence, cross-species infection, and adaptation in the laboratory mouse von Nennig, Kylie, Murthy, Satyapramod, Maloney, Sara, Shaw, Teressa M, Sharobim, Mark, Matkovic, Eduard, Fadiran, Simi, Larsen, Malorie, Ramuta, Mitchell D, Kim, Arthur S, Teijaro, John R, Grove, Joe, Stremlau, Matthew, Sharma, Himanshu, Trivedi, Sheetal, Blum, Michael J, O'Connor, David H, Hyde, Jennifer L, Stapleton, Jack T, Kapoor, Amit, Bailey, Adam L

Volltext

Subcellular localization of the MNV-1 ORF1 proteins and their potential roles in the formation of the MNV-1 replication complex von Hyde, Jennifer L, Mackenzie, Jason M

Volltext

Oropouche virus infection and pathogenesis are restricted by MAVS, IRF-3, IRF-7, and type I interferon signaling pathways in nonmyeloid cells von Proenca-Modena, Jose Luiz, Sesti-Costa, Renata, Pinto, Amelia K, Richner, Justin M, Lazear, Helen M, Lucas, Tiffany, Hyde, Jennifer L, Diamond, Michael S

Volltext

Endomembrane targeting of human OAS1 p46 augments antiviral activity von Soveg, Frank W, Schwerk, Johannes, Gokhale, Nandan S, Cerosaletti, Karen, Smith, Julian R, Pairo-Castineira, Erola, Kell, Alison M, Forero, Adriana, Zaver, Shivam A, Esser-Nobis, Katharina, Roby, Justin A, Hsiang, Tien-Ying, Ozarkar, Snehal, Clingan, Jonathan M, McAnarney, Eileen T, Stone, Amy El, Malhotra, Uma, Speake, Cate, Perez, Joseph, Balu, Chiraag, Allenspach, Eric J, Hyde, Jennifer L, Menachery, Vineet D, Sarkar, Saumendra N, Woodward, Joshua J, Stetson, Daniel B, Baillie, John Kenneth, Buckner, Jane H, Gale, Jr, Michael, Savan, Ram

Volltext

Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System von Proenca-Modena, Jose Luiz, Hyde, Jennifer L, Sesti-Costa, Renata, Lucas, Tiffany, Pinto, Amelia K, Richner, Justin M, Gorman, Matthew J, Lazear, Helen M, Diamond, Michael S

Volltext

Mouse Norovirus infection promotes autophagy induction to facilitate replication but prevents final autophagosome maturation von O’Donnell, Tanya B, Hyde, Jennifer L, Mintern, Justine D, Mackenzie, Jason M

Volltext