Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer von Öhlund, Daniel, Handly-Santana, Abram, Biffi, Giulia, Elyada, Ela, Almeida, Ana S, Ponz-Sarvise, Mariano, Corbo, Vincenzo, Oni, Tobiloba E, Hearn, Stephen A, Lee, Eun Jung, Chio, Iok In Christine, Hwang, Chang-Il, Tiriac, Hervé, Baker, Lindsey A, Engle, Dannielle D, Feig, Christine, Kultti, Anne, Egeblad, Mikala, Fearon, Douglas T, Crawford, James M, Clevers, Hans, Park, Youngkyu, Tuveson, David A

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Preclinical models of pancreatic ductal adenocarcinoma von Hwang, Chang-Il, Boj, Sylvia F, Clevers, Hans, Tuveson, David A

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Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade von Nielsen, Sebastian R., Strøbech, Jan E., Horton, Edward R., Jackstadt, Rene, Laitala, Anu, Bravo, Marina C., Maltese, Giorgia, Jensen, Adina R. D., Reuten, Raphael, Rafaeva, Maria, Karim, Saadia A., Hwang, Chang-Il, Arnes, Luis, Tuveson, David A., Sansom, Owen J., Morton, Jennifer P., Erler, Janine T.

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Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche von Flesken-Nikitin, Andrea, Hwang, Chang-Il, Cheng, Chieh-Yang, Michurina, Tatyana V., Enikolopov, Grigori, Nikitin, Alexander Yu

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Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis von Roe, Jae-Seok, Hwang, Chang-Il, Somerville, Tim D.D., Milazzo, Joseph P., Lee, Eun Jung, Da Silva, Brandon, Maiorino, Laura, Tiriac, Hervé, Young, C. Megan, Miyabayashi, Koji, Filippini, Dea, Creighton, Brianna, Burkhart, Richard A., Buscaglia, Jonathan M., Kim, Edward J., Grem, Jean L., Lazenby, Audrey J., Grunkemeyer, James A., Hollingsworth, Michael A., Grandgenett, Paul M., Egeblad, Mikala, Park, Youngkyu, Tuveson, David A., Vakoc, Christopher R.

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SOAT1 promotes mevalonate pathway dependency in pancreatic cancer von Oni, Tobiloba E., Biffi, Giulia, Baker, Lindsey A., Hao, Yuan, Tonelli, Claudia, Somerville, Tim D. D., Deschenes, Astrid, Belleau, Pascal, Hwang, Chang-il, Sanchez-Rivera, Francisco J., Cox, Hilary, Brosnan, Erin, Doshi, Abhishek, Lumia, Rebecca P., Khaledi, Kimia, Park, Youngkyu, Trotman, Lloyd C., Lowe, Scott W., Krasnitz, Alexander, Vakoc, Christopher R., Tuveson, David A.

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Intraductal Transplantation Models of Human Pancreatic Ductal Adenocarcinoma Reveal Progressive Transition of Molecular Subtypes von Miyabayashi, Koji, Baker, Lindsey A., Deschenes, Astrid, Traub, Benno, Caligiuri, Giuseppina, Plenker, Dennis, Alagesan, Brinda, Belleau, Pascal, Li, Siran, Kendall, Jude, Jang, Gun Ho, Kawaguchi, Risa Karakida, Somerville, Tim D. D., Tiriac, Herve, Hwang, Chang-Il, Burkhart, Richard A., Roberts, Nicholas J., Wood, Laura D., Hruban, Ralph H., Gillis, Jesse, Krasnitz, Alexander, Vakoc, Christopher R., Wigler, Michael, Notta, Faiyaz, Gallinger, Steven, Park, Youngkyu, Tuveson, David A.

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Frequent Downregulation of miR-34 Family in Human Ovarian Cancers von CORNEY, David C, HWANG, Chang-Ii, NIKITIN, Alexander Yu, MATOSO, Andres, VOGT, Markus, FLESKEN-NIKITIN, Andrea, GODWIN, Andrew K, KAMAT, Aparna A, SOOD, Anil K, ELLENSON, Lora H, HERMEKING, Heiko

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KMT2A associates with PHF5A-PHF14-HMG20A-RAI1 subcomplex in pancreatic cancer stem cells and epigenetically regulates their characteristics von Mouti, Mai Abdel, Deng, Siwei, Pook, Martin, Malzahn, Jessica, Rendek, Aniko, Militi, Stefania, Nibhani, Reshma, Soonawalla, Zahir, Oppermann, Udo, Hwang, Chang-il, Pauklin, Siim

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Single-Cell Network-Based Drug Repositioning for Discovery of Therapies against Anti-Tumour Necrosis Factor-Resistant Crohn’s Disease von Kwak, Min Seob, Hwang, Chang-Il, Cha, Jae Myung, Jeon, Jung Won, Yoon, Jin Young, Park, Su Bee

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Epigenetic Alterations in Pancreatic Cancer Metastasis von Wang, Sarah S., Xu, Jihao, Ji, Keely Y., Hwang, Chang-Il

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Germline Aberrations in Pancreatic Cancer: Implications for Clinical Care von Casolino, Raffaella, Corbo, Vincenzo, Beer, Philip, Hwang, Chang-Il, Paiella, Salvatore, Silvestri, Valentina, Ottini, Laura, Biankin, Andrew V

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Wild-type p53 controls cell motility and invasion by dual regulation of MET expression von Hwang, Chang-Il, Matoso, Andres, Corney, David C, Flesken-Nikitin, Andrea, Körner, Stefanie, Wang, Wei, Boccaccio, Carla, Thorgeirsson, Snorri S, Comoglio, Paolo M, Hermeking, Heiko, Nikitin, Alexander Yu

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SEMA3C Supports Pancreatic Cancer Progression by Regulating the Autophagy Process and Tumor Immune Microenvironment von Zhang, Dalin, Lindstrom, Aaron, Kim, Edward J, Hwang, Chang-Il, Hall, Madison Lee, Lin, Tzu-Yin, Li, Yuanpei

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A new vulnerability to BET inhibition due to enhanced autophagy in BRCA2 deficient pancreatic cancer von Lee, EunJung, Archasappawat, Suyakarn, Ji, Keely, Pena, Jocelyn, Fernandez-Vega, Virneliz, Gangaraju, Ritika, Beesabathuni, Nitin Sai, Kim, Martin Jean, Tian, Qi, Shah, Priya S., Scampavia, Louis, Spicer, Timothy P., Hwang, Chang-Il

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Engrailed‐1 Promotes Pancreatic Cancer Metastasis von Xu, Jihao, Roe, Jae‐Seok, Lee, EunJung, Tonelli, Claudia, Ji, Keely Y., Younis, Omar W., Somervile, Tim D.D., Yao, Melissa, Milazzo, Joseph P., Tiriac, Herve, Kolarzyk, Anna M., Lee, Esak, Grem, Jean L., Lazenby, Audrey J., Grunkemeyer, James A., Hollingsworth, Michael A., Grandgenett, Paul M., Borowsky, Alexander D., Park, Youngkyu, Vakoc, Christopher R., Tuveson, David A., Hwang, Chang‐Il

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miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment von Cheng, Chieh-Yang, Hwang, Chang-Il, Corney, David C, Flesken-Nikitin, Andrea, Jiang, Longchang, Öner, Gülfem Meryem, Munroe, Robert J, Schimenti, John C, Hermeking, Heiko, Nikitin, Alexander Yu

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Genomic heterogeneity in pancreatic cancer organoids and its stability with culture von Usman, Olalekan H., Zhang, Liting, Xie, Gengqiang, Kocher, Hemant M., Hwang, Chang-il, Wang, Yue Julia, Mallory, Xian, Irianto, Jerome

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Whole-genome bisulfite sequencing identifies stage- and subtype-specific DNA methylation signatures in pancreatic cancer von Wang, Sarah S., Hall, Madison L., Lee, EunJung, Kim, Soon-Chan, Ramesh, Neha, Lee, Sang Hyub, Jang, Jin-Young, Bold, Richard J., Ku, Ja-Lok, Hwang, Chang-Il

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Organoid Models of Human and Mouse Ductal Pancreatic Cancer von Boj, Sylvia F., Hwang, Chang-Il, Baker, Lindsey A., Chio, Iok In Christine, Engle, Dannielle D., Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S., Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H., van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D., Wilson, John P., Feigin, Michael E., Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M., Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N., Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H.M., Molenaar, I. Quintus, Borel Rinkes, Inne H., Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J., Iacobuzio-Donahue, Christine, Leach, Steven D., Pappin, Darryl J., Hammell, Molly, Klimstra, David S., Basturk, Olca, Hruban, Ralph H., Offerhaus, George Johan, Vries, Robert G.J., Clevers, Hans, Tuveson, David A.

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