Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms von Huston, Nicholas C., Wan, Han, Strine, Madison S., de Cesaris Araujo Tavares, Rafael, Wilen, Craig B., Pyle, Anna Marie

Volltext

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes von Ravindra, Neal G, Alfajaro, Mia Madel, Gasque, Victor, Huston, Nicholas C, Wan, Han, Szigeti-Buck, Klara, Yasumoto, Yuki, Greaney, Allison M, Habet, Victoria, Chow, Ryan D, Chen, Jennifer S, Wei, Jin, Filler, Renata B, Wang, Bao, Wang, Guilin, Niklason, Laura E, Montgomery, Ruth R, Eisenbarth, Stephanie C, Chen, Sidi, Williams, Adam, Iwasaki, Akiko, Horvath, Tamas L, Foxman, Ellen F, Pierce, Richard W, Pyle, Anna Marie, van Dijk, David, Wilen, Craig B

Volltext

Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis von Kardon, Julia R., Yien, Yvette Y., Huston, Nicholas C., Branco, Diana S., Hildick-Smith, Gordon J., Rhee, Kyu Y., Paw, Barry H., Baker, Tania A.

Volltext

The global and local distribution of RNA structure throughout the SARS-CoV-2 genome von Tavares, Rafael de Cesaris Araujo, Mahadeshwar, Gandhar, Wan, Han, Huston, Nicholas C, Pyle, Anna Marie

Volltext

Sequencing and Structure Probing of Long RNAs Using MarathonRT: A Next-Generation Reverse Transcriptase von Guo, Li-Tao, Adams, Rebecca L., Wan, Han, Huston, Nicholas C., Potapova, Olga, Olson, Sara, Gallardo, Christian M., Graveley, Brenton R., Torbett, Bruce E., Pyle, Anna Marie

Volltext

Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals von Grillo, Anthony S., SantaMaria, Anna M., Kafina, Martin D., Cioffi, Alexander G., Huston, Nicholas C., Han, Murui, Seo, Young Ah, Yien, Yvette Y., Nardone, Christopher, Menon, Archita V., Fan, James, Svoboda, Dillon C., Anderson, Jacob B., Hong, John D., Nicolau, Bruno G., Subedi, Kiran, Gewirth, Andrew A., Wessling-Resnick, Marianne, Kim, Jonghan, Paw, Barry H., Burke, Martin D.

Volltext

The West Nile virus genome harbors essential riboregulatory elements with conserved and host-specific functional roles von Huston, Nicholas C, Tsao, Lucille H, Brackney, Doug E, Pyle, Anna Marie

Volltext

Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells von Tycko, Josh, Barrera, Luis A., Huston, Nicholas C., Friedland, Ari E., Wu, Xuebing, Gootenberg, Jonathan S., Abudayyeh, Omar O., Myer, Vic E., Wilson, Christopher J., Hsu, Patrick D.

Volltext

The SMN complex drives structural changes in human snRNAs to enable snRNP assembly von Pánek, Josef, Roithová, Adriana, Radivojević, Nenad, Sýkora, Michal, Prusty, Archana Bairavasundaram, Huston, Nicholas, Wan, Han, Pyle, Anna Marie, Fischer, Utz, Staněk, David

Volltext

Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes von Seguin, Alexandra, Takahashi-Makise, Naoko, Yien, Yvette Y., Huston, Nicholas C., Whitman, Jared C., Musso, Gabriel, Wallace, Jared A., Bradley, Thomas, Bergonia, Hector A., Kafina, Martin D., Matsumoto, Mitsuyo, Igarashi, Kazuhiko, Phillips, John D., Paw, Barry H., Kaplan, Jerry, Ward, Diane M.

Volltext

Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia von Crispin, Andrew, Guo, Chaoshe, Chen, Caiyong, Campagna, Dean R, Schmidt, Paul J, Lichtenstein, Daniel, Cao, Chang, Sendamarai, Anoop K, Hildick-Smith, Gordon J, Huston, Nicholas C, Boudreaux, Jeanne, Bottomley, Sylvia S, Heeney, Matthew M, Paw, Barry H, Fleming, Mark D, Ducamp, Sarah

Volltext

Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells von Tycko, Josh, Barrera, Luis A., Huston, Nicholas C., Friedland, Ari E., Wu, Xuebing, Gootenberg, Jonathan S., Abudayyeh, Omar O., Myer, Vic E., Wilson, Christopher J., Hsu, Patrick D.

Volltext

The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability von Chung, Jacky, Bauer, Daniel E, Ghamari, Alireza, Nizzi, Christopher P, Deck, Kathryn M, Kingsley, Paul D, Yien, Yvette Y, Huston, Nicholas C, Chen, Caiyong, Schultz, Iman J, Dalton, Arthur J, Wittig, Johannes G, Palis, James, Orkin, Stuart H, Lodish, Harvey F, Eisenstein, Richard S, Cantor, Alan B, Paw, Barry H

Volltext

Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia von Shmukler, Boris E, Huston, Nicholas C, Thon, Jonathan N, Ni, Chih-Wen, Kourkoulis, George, Lawson, Nathan D, Paw, Barry H, Alper, Seth L

Volltext

Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression von Anderson, Heidi, Patch, Taylor C., Reddy, Pavankumar N.G., Hagedorn, Elliott J., Kim, Peter G., Soltis, Kathleen A., Chen, Michael J., Tamplin, Owen J., Frye, Maike, MacLean, Glenn A., Hübner, Kathleen, Bauer, Daniel E., Kanki, John P., Vogin, Guillaume, Huston, Nicholas C., Nguyen, Minh, Fujiwara, Yuko, Paw, Barry H., Vestweber, Dietmar, Zon, Leonard I., Orkin, Stuart H., Daley, George Q., Shah, Dhvanit I.

Volltext

Macrocytic Anemia and Mitochondriopathy Resulting from a Defect in Sideroflexin 4 von Hildick-Smith, Gordon J., Cooney, Jeffrey D., Garone, Caterina, Kremer, Laura S., Haack, Tobias B., Thon, Jonathan N., Miyata, Non, Lieber, Daniel S., Calvo, Sarah E., Akman, H. Orhan, Yien, Yvette Y., Huston, Nicholas C., Branco, Diana S., Shah, Dhvanit I., Freedman, Matthew L., Koehler, Carla M., Italiano, Joseph E., Merkenschlager, Andreas, Beblo, Skadi, Strom, Tim M., Meitinger, Thomas, Freisinger, Peter, Donati, M. Alice, Prokisch, Holger, Mootha, Vamsi K., DiMauro, Salvatore, Paw, Barry H.

Volltext

Iron Regulatory Protein-1 Protects against Mitoferrin-1-deficient Porphyria von Chung, Jacky, Anderson, Sheila A., Gwynn, Babette, Deck, Kathryn M., Chen, Michael J., Langer, Nathaniel B., Shaw, George C., Huston, Nicholas C., Boyer, Leah F., Datta, Sumon, Paradkar, Prasad N., Li, Liangtao, Wei, Zong, Lambert, Amy J., Sahr, Kenneth, Wittig, Johannes G., Chen, Wen, Lu, Wange, Galy, Bruno, Schlaeger, Thorsten M., Hentze, Matthias W., Ward, Diane M., Kaplan, Jerry, Eisenstein, Richard S., Peters, Luanne L., Paw, Barry H.

Volltext

Sensitive detection of structural features and rearrangements in long, structured RNA molecules von Adams, Rebecca L, Huston, Nicholas C, Tavares, Rafael C A, Pyle, Anna M

Volltext

Identification of the Vertebrate RIM2 Ortholog by Genetic Complementation for Heme von M. Cabañero, Javier, Nguyen, An, Huston, Nicholas, Knight, Simon, Dancis, Andrew, Paw, Barry

Volltext

Sideroflexin 4 Deficiency Results In An Erythroid Differentiation Defect von Nwanaji-Enwerem, Jamaji C., Hildick-Smith, Gordon J., Bauer, Daniel E., Huston, Nicholas, Paw, Barry H.

Volltext