A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia von Zeng, Andy G. X., Bansal, Suraj, Jin, Liqing, Mitchell, Amanda, Chen, Weihsu Claire, Abbas, Hussein A., Chan-Seng-Yue, Michelle, Voisin, Veronique, van Galen, Peter, Tierens, Anne, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Daver, Naval, Futreal, P. Andrew, Minden, Mark D., Kennedy, James A., Wang, Jean C. Y., Dick, John E.

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Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance von Chu, Yanshuo, Dai, Enyu, Li, Yating, Han, Guangchun, Pei, Guangsheng, Ingram, Davis R., Thakkar, Krupa, Qin, Jiang-Jiang, Dang, Minghao, Le, Xiuning, Hu, Can, Deng, Qing, Sinjab, Ansam, Gupta, Pravesh, Wang, Ruiping, Hao, Dapeng, Peng, Fuduan, Yan, Xinmiao, Liu, Yunhe, Song, Shumei, Zhang, Shaojun, Heymach, John V., Reuben, Alexandre, Elamin, Yasir Y., Pizzi, Melissa P., Lu, Yang, Lazcano, Rossana, Hu, Jian, Li, Mingyao, Curran, Michael, Futreal, Andrew, Maitra, Anirban, Jazaeri, Amir A., Ajani, Jaffer A., Swanton, Charles, Cheng, Xiang-Dong, Abbas, Hussein A., Gillison, Maura, Bhat, Krishna, Lazar, Alexander J., Green, Michael, Litchfield, Kevin, Kadara, Humam, Yee, Cassian, Wang, Linghua

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Acalabrutinib: A Selective Bruton Tyrosine Kinase Inhibitor for the Treatment of B-Cell Malignancies von Abbas, Hussein A., Wierda, William G.

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Accurate identification of locally aneuploid cells by incorporating cytogenetic information in single cell data analysis von Li, Ziyi, Li, Ruoxing, Ganan-Gomez, Irene, Abbas, Hussein A., Garcia-Manero, Guillermo, Sun, Wei

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Immune dysfunction signatures predict outcomes and define checkpoint blockade-unresponsive microenvironments in acute myeloid leukemia von Rutella, Sergio, Vadakekolathu, Jayakumar, Mazziotta, Francesco, Reeder, Stephen, Yau, Tung-On, Mukhopadhyay, Rupkatha, Dickins, Benjamin, Altmann, Heidi, Kramer, Michael, Knaus, Hanna A, Blazar, Bruce R, Radojcic, Vedran, Zeidner, Joshua F, Arruda, Andrea, Wang, Bofei, Abbas, Hussein A, Minden, Mark D, Tasian, Sarah K, Bornhäuser, Martin, Gojo, Ivana, Luznik, Leo

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Outcomes and genetic dynamics of acute myeloid leukemia at first relapse von Bataller, Alex, Kantarjian, Hagop, Bazinet, Alexandre, Kadia, Tapan, Daver, Naval, DiNardo, Courtney D, Borthakur, Gautam, Loghavi, Sanam, Patel, Keyur, Tang, Guilin, Sasaki, Koji, Short, Nicholas J, Yilmaz, Musa, Issa, Ghayas C, Alvarado, Yesid, Montalban-Bravo, Guillermo, Maiti, Abhishek, Abbas, Hussein A, Takahashi, Koichi, Pierce, Sherry, Jabbour, Elias, Garcia-Manero, Guillermo, Ravandi, Farhad

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Comprehensive characterization of IFNγ signaling in acute myeloid leukemia reveals prognostic and therapeutic strategies von Wang, Bofei, Reville, Patrick K., Yassouf, Mhd Yousuf, Jelloul, Fatima Z., Ly, Christopher, Desai, Poonam N., Wang, Zhe, Borges, Pamella, Veletic, Ivo, Dasdemir, Enes, Burks, Jared K., Tang, Guilin, Guo, Shengnan, Garza, Araceli Isabella, Nasnas, Cedric, Vaughn, Nicole R., Baran, Natalia, Deng, Qing, Matthews, Jairo, Gunaratne, Preethi H., Antunes, Dinler A., Ekmekcioglu, Suhendan, Sasaki, Koji, Garcia, Miriam B., Cuglievan, Branko, Hao, Dapeng, Daver, Naval, Green, Michael R., Konopleva, Marina, Futreal, Andrew, Post, Sean M., Abbas, Hussein A.

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The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity von Pant, Vinod, Xiong, Shunbin, Jackson, James G, Post, Sean M, Abbas, Hussein A, Quintás-Cardama, Alfonso, Hamir, Amirali N, Lozano, Guillermina

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Impact of p53-associated acute myeloid leukemia hallmarks on metabolism and the immune environment von Chomczyk, Monika, Gazzola, Luca, Dash, Shubhankar, Firmanty, Patryk, George, Binsah S, Mohanty, Vakul, Abbas, Hussein A, Baran, Natalia

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Author Correction: ΔNp63 regulates a common landscape of enhancer associated genes in non-small cell lung cancer von Napoli, Marco, Wu, Sarah J., Gore, Bethanie L., Abbas, Hussein A., Lee, Kyubum, Checker, Rahul, Dhar, Shilpa, Rajapakshe, Kimal, Tan, Aik Choon, Lee, Min Gyu, Coarfa, Cristian, Flores, Elsa R.

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The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics von Tang, Ming, Abbas, Hussein A., Negrao, Marcelo V., Ramineni, Maheshwari, Hu, Xin, Hubert, Shawna Marie, Fujimoto, Junya, Reuben, Alexandre, Varghese, Susan, Zhang, Jianhua, Li, Jun, Chow, Chi-Wan, Mao, Xizeng, Song, Xingzhi, Lee, Won-Chul, Wu, Jia, Little, Latasha, Gumbs, Curtis, Behrens, Carmen, Moran, Cesar, Weissferdt, Annikka, Lee, J. Jack, Sepesi, Boris, Swisher, Stephen, Cheng, Chao, Kurie, Jonathan, Gibbons, Don, Heymach, John V., Wistuba, Ignacio I., Futreal, P. Andrew, Kalhor, Neda, Zhang, Jianjun

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Mdm2 Is Required for Survival of Hematopoietic Stem Cells/Progenitors via Dampening of ROS-Induced p53 Activity von Abbas, Hussein A., Maccio, Daniela R., Coskun, Suleyman, Jackson, James G., Hazen, Amy L., Sills, Tiffany M., You, M. James, Hirschi, Karen K., Lozano, Guillermina

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Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes von Abbas, Hussein A., Reville, Patrick K., Jiang, Xianli, Yang, Hui, Reuben, Alexandre, Im, Jin Seon, Little, Latasha, Sinson, Jefferson C., Chen, Ken, Futreal, Andrew, Garcia-Manero, Guillermo

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Paired single-B-cell transcriptomics and receptor sequencing reveal activation states and clonal signatures that characterize B cells in acute myeloid leukemia von Guo, Shengnan, Mohan, Gopi S, Wang, Bofei, Li, Tianhao, Daver, Naval, Zhao, Yuting, Reville, Patrick K, Hao, Dapeng, Abbas, Hussein A

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Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance von Fan, Huihui, Wang, Feng, Zeng, Andy, Murison, Alex, Tomczak, Katarzyna, Hao, Dapeng, Jelloul, Fatima Zahra, Wang, Bofei, Barrodia, Praveen, Liang, Shaoheng, Chen, Ken, Wang, Linghua, Zhao, Zhongming, Rai, Kunal, Jain, Abhinav K., Dick, John, Daver, Naval, Futreal, Andy, Abbas, Hussein A.

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A Phase I study of Milademetan (DS3032b) in combination with low dose cytarabine with or without venetoclax in acute myeloid leukemia: Clinical safety, efficacy, and correlative an... von Senapati, Jayastu, Muftuoglu, Muharrem, Ishizawa, Jo, Abbas, Hussein A., Loghavi, Sanam, Borthakur, Gautam, Yilmaz, Musa, Issa, Ghayas C., Dara, Samuel I., Basyal, Mahesh, Li, Li, Naqvi, Kiran, Pourebrahim, Rasoul, Jabbour, Elias J., Kornblau, Steven M., Short, Nicholas J., Pemmaraju, Naveen, Garcia-Manero, Guillermo, Ravandi, Farhad, Khoury, Joseph, Daver, Naval, Kantarjian, Hagop M., Andreeff, Michael, DiNardo, Courtney D.

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Nontuberculosis mycobacteria (NTM) infections in patients with leukemia: a single center case series von Marvin-Peek, Jennifer, Sasaki, Koji, Kontoyiannis, Dimitrios P, Adachi, Javier, Ohanian, Maro, Takahashi, Koichi, Issa, Ghayas C, Kornblau, Steven, Abbas, Hussein A

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Novel Cancer Immunotherapies and Antitumor Immunity von Zhao, Lei, Zhang, Jianjun, Xu, Liang, Abbas, Hussein A.

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The ups and downs of p53 regulation in hematopoietic stem cells von Abbas, Hussein A., Pant, Vinod, Lozano, Guillermina

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Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes von Abbas, Hussein A., Mohanty, Vakul, Wang, Ruiping, Huang, Yuefan, Liang, Shaoheng, Wang, Feng, Zhang, Jianhua, Qiu, Yihua, Hu, Chenyue W., Qutub, Amina A., Dail, Monique, Bolen, Christopher R., Daver, Naval, Konopleva, Marina, Futreal, Andrew, Chen, Ken, Wang, Linghua, Kornblau, Steven M.

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