Impaired neural development in a zebrafish model for Lowe syndrome von RAMIREZ, Irene Barinaga-Rementeria, PIETKA, Grzegorz, JONES, David R, DIVECHA, Nullin, ALIA, A, BARABAN, Scott C, HURLSTONE, Adam F. L, LOWE, Martin

Volltext

PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models von Wong, Chun Wai, Evangelou, Christos, Sefton, Kieran N., Leshem, Rotem, Zhang, Wei, Gopalan, Vishaka, Chattrakarn, Sorayut, Fernandez Carro, Macarena Lucia, Uzuner, Erez, Mole, Holly, Wilcock, Daniel J., Smith, Michael P., Sergiou, Kleita, Telfer, Brian A., Isaac, Dervla T., Liu, Chang, Perl, Nicholas R., Marie, Kerrie, Lorigan, Paul, Williams, Kaye J., Rao, Patricia E., Nagaraju, Raghavendar T., Niepel, Mario, Hurlstone, Adam F. L.

Volltext

rnaset2 mutant zebrafish model familial cystic leukoencephalopathy and reveal a role for RNase T2 in degrading ribosomal RNA von Haud, Noémie, Kara, Firat, Diekmann, Simone, Henneke, Marco, Willer, Jason R., Hillwig, Melissa S., Gregg, Ronald G., MacIntosh, Gustavo C., Gärtner, Jutta, Alia, A., Hurlstone, Adam F. L., Moore, Melissa J.

Volltext

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell-like Populations and Diverse Mononuclear Phagocytes von Dee, Christopher T, Nagaraju, Raghavendar T, Athanasiadis, Emmanouil I, Gray, Caroline, Fernandez Del Ama, Laura, Johnston, Simon A, Secombes, Christopher J, Cvejic, Ana, Hurlstone, Adam F L

Volltext

The Wnt/β-catenin pathway regulates cardiac valve formation von Clevers, Hans, Hurlstone, Adam F. L, Haramis, Anna-Pavlina G, Wienholds, Erno, Begthel, Harry, Korving, Jeroen, van Eeden, Fredericus, Cuppen, Edwin, Zivkovic, Danica, Plasterk, Ronald H. A

Volltext

Impaired neural development in a zebrafish model for Lowe syndrome von Ramirez, Irene Barinaga-Rementeria, Pietka, Grzegorz, Jones, David R, Divecha, Nullin, Alia, A, Baraban, Scott C, Hurlstone, Adam F L, Lowe, Martin

Volltext

Zebrafish IL-4-like Cytokines and IL-10 Suppress Inflammation but Only IL-10 Is Essential for Gill Homeostasis von Bottiglione, Federica, Dee, Christopher T., Lea, Robert, Zeef, Leo A. H., Badrock, Andrew P., Wane, Madina, Bugeon, Laurence, Dallman, Margaret J., Allen, Judith E., Hurlstone, Adam F. L.

Volltext

Dissecting the roles of Raf- and PI3K-signalling pathways in melanoma formation and progression in a zebrafish model von Michailidou, Christina, Jones, Mary, Walker, Paul, Kamarashev, Jivko, Kelly, Amanda, Hurlstone, Adam F L

Volltext

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells von Diamantopoulou, Zoi, White, Gavin, Fadlullah, Muhammad Z.H., Dreger, Marcel, Pickering, Karen, Maltas, Joe, Ashton, Garry, MacLeod, Ruth, Baillie, George S., Kouskoff, Valerie, Lacaud, Georges, Murray, Graeme I., Sansom, Owen J., Hurlstone, Adam F.L., Malliri, Angeliki

Volltext

The Rac Activator Tiam1 Is a Wnt-responsive Gene That Modifies Intestinal Tumor Development von Malliri, Angeliki, Rygiel, Tomasz P., van der Kammen, Rob A., Song, Ji-Ying, Engers, Rainer, Hurlstone, Adam F.L., Clevers, Hans, Collard, John G.

Volltext

Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached von Wilcock, Daniel J., Badrock, Andrew P., Wong, Chun W., Owen, Rhys, Guerin, Melissa, Southam, Andrew D., Johnston, Hannah, Telfer, Brian A., Fullwood, Paul, Watson, Joanne, Ferguson, Harriet, Ferguson, Jennifer, Lloyd, Gavin R., Jankevics, Andris, Dunn, Warwick B., Wellbrock, Claudia, Lorigan, Paul, Ceol, Craig, Francavilla, Chiara, Smith, Michael P., Hurlstone, Adam F.L.

Volltext

HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion von Vaughan, Lynsey, Tan, Chong-Teik, Chapman, Anna, Nonaka, Daisuke, Mack, Natalie A., Smith, Duncan, Booton, Richard, Hurlstone, Adam F.L., Malliri, Angeliki

Volltext

Reprofiling using a zebrafish melanoma model reveals drugs cooperating with targeted therapeutics von Fernandez Del Ama, Laura, Jones, Mary, Walker, Paul, Chapman, Anna, Braun, Julia A, Mohr, Jasmine, Hurlstone, Adam F L

Volltext

Glucose uptake as an alternative to oxygen uptake for assessing metabolic rate in Danio rerio larvae von Evans, Bridget L., Hurlstone, Adam F.L., Clayton, Peter E., Stevens, Adam, Shiels, Holly A.

Volltext

T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine von Muncan, Vanesa, Faro, Ana, Haramis, Anna-Pavlina G, Hurlstone, Adam F L, Wienholds, Erno, van Es, Johan, Korving, Jeroen, Begthel, Harry, Zivkovic, Danica, Clevers, Hans

Volltext

The Transcription Factor AP-1 Is Required for EGF-Induced Activation of Rho-Like GTPases, Cytoskeletal Rearrangements, Motility, and in vitro Invasion of A431 Cells von Malliri, Angeliki, Symons, Marc, Hennigan, Robert F., Adam F. L. Hurlstone, Lamb, Richard F., Wheeler, Tricia, Ozanne, Bradford W.

Volltext

Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines von HURLSTONE, A. F, REID, G, REEVES, J. R, FRASER, J, STRATHDEE, G, RAHILLY, M, PARKINSON, E. K, BLACK, D. M

Volltext

Absence of ST7 mutations in tumor-derived cell lines and tumors von Black, Donald M, Hughes, Kate A, Hurlstone, Adam F.L, Tobias, Edward S, McFarlane, Robert

Volltext

Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQQ209P-driven uveal melanomas in zebrafish von Mouti, Mai Abdel, Dee, Christopher, Coupland, Sarah E, Hurlstone, Adam F L

Volltext

Identification of multiple integrin β1 homologs in zebrafish (Danio rerio) von Mould, A Paul, McLeish, Jennifer A, Huxley-Jones, Julie, Goonesinghe, Alexander C, Hurlstone, Adam FL, Boot-Handford, Raymond P, Humphries, Martin J

Volltext