Matrix metalloproteinases von Johnson, Linda L, Dyer, Richard, Hupe, Donald J

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A Rationalization of the Acidic pH Dependence for Stromelysin-1 (Matrix Metalloproteinase-3) Catalysis and Inhibition von Johnson, Linda L., Pavlovsky, Alexander G., Johnson, Adam R., Janowicz, Jeffrey A., Man, Chiu-Fai, Ortwine, Daniel F., Purchase, Claude F., White, Andrew D., Hupe, Donald J.

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Novel Drimane Sesquiterpene Esters from Aspergillus ustus var. pseudodeflectus with Endothelin Receptor Binding Activity von HAYES, MARTIN A., WRIGLEY, STEPHEN K., CHETLAND, IAN, REYNOLDS, ELWOOD E., AINSWORTH, A. MARTYN, RENNO, DIDIER V., LATIF, MOHAMMED A., CHENG, XUE-MIN, HUPE, DONALD J., CHARLTON, PETER, DOHERTY, ANNETTE M.

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Purification and characterization of the human stromelysin catalytic domain expressed in Escherichia coli von Ye, Qi Zhuang, Johnson, Linda L, Hupe, Donald J, Baragi, Vijaykumar

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Synergy between Anions and Farnesyldiphosphate Competitive Inhibitors of Farnesyl:Protein Transferase von Scholten, Jeffrey D., Zimmerman, Karen K., Oxender, Maritza G., Leonard, Daniele, Sebolt-Leopold, Judith, Gowan, Richard, Hupe, Donald J.

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Pyridinone Derivatives: Specific Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors with Antiviral Activity von Goldman, Mark E., Nunberg, Jack H., O'Brien, Julie A., Quintero, Julio C., Schleif, William A., Freund, Kurt F., Gaul, S. Lee, Saari, Walfred S., Wai, John S., Hoffman, Jacob M., Anderson, Paul S., Hupe, Donald J., Emini, Emilio A., Stern, Andrew M.

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Amine catalysis of .beta.-ketol dehydration. II. Catalysis via iminium ion formation. General analysis of nucleophilic amine catalysis von Hupe, Donald J, Kendall, Martha C. R, Spencer, Thomas A

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Solution structure of the catalytic domain of human stromelysin complexed with a hydrophobic inhibitor von Van Doren, Steven R., Kurochkin, Alexander V., Hu, Weidong, Ye, Qi‐Zhuang, Johnson, Linda L., Hupe, Donald J., Zuiderweg, ERIK R.P.

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High-level expression of rat farnesyl:protein transferase in Escherichia coli as a translationally coupled heterodimer von Zimmerman, K K, Scholten, J D, Huang, C C, Fierke, C A, Hupe, D J

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The inhibition of receptor-mediated and voltage-dependent calcium entry by the antiproliferative L-651,582 von HUPE, D. J, BOLTZ, R, COHEN, C. J, FELIX, J, HAM, E, MILLER, D, SODERMAN, D, VAN SKIVER, D

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Assignments for the main-chain nuclear magnetic resonances and delineation of the secondary structure of the catalytic domain of human stromelysin-1 as obtained from triple-resonan... von Van Doren, Steven R., Kurochkin, Alexander V., Ye, Qi Zhuang, Johnson, Linda L., Hupe, Donald J., Zuiderweg, Erik R. P.

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Inhibitors of farnesyl:protein transferase—A possible cancer chemotherapeutic von Scholten, Jeffrey D., Zimmerman, Karen, Oxender, Maritza, Sebolt-Leopold, Judith, Gowan, Richard, Leonard, Daniele, Hupe, Donald J.

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Discovery and optimization of nonpeptide HIV-1 protease inhibitors von Tummino, Peter J., Vara Prasad, J.V.N., Ferguson, Donna, Nouhan, Carolyn, Graham, Neil, Domagala, John M., Ellsworth, Edmund, Gajda, Christopher, Hagen, Susan E., Lunney, Elizabeth A., Para, Kimberly S., Tait, Bradley D., Pavlovsky, Alexander, Erickson, John W., Gracheck, Stephen, McQuade, Thomas J., Hupe, Donald J.

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High-Level Expression of Rat Farnesyl:Protein Transferase inEscherichia colias a Translationally Coupled Heterodimer von Zimmerman, Karen K., Scholten, Jeffrey D., Huang, Chih-chin, Fierke, Carol A., Hupe, Donald J.

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HIV1 integrase expressed in Escherichia coli from a synthetic gene von Holler, Tod P., Foltin, Susan K., Ye, Qi-Zhuang, Hupe, Donald J.

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Amine catalysis of elimination from .beta.-acetoxy ketone. Catalysis via iminium ion formation von Hupe, Donald J, Kendall, Martha C. R, Spencer, Thomas A

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Amine catalysis of .beta.-ketol dehydration. I. Catalysis by aqueous solutions of tertiary amines von Hupe, Donald J, Kendall, Martha C. R, Sinner, Gregory T, Spencer, Thomas A

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Anti-proliferative activity of L-651,582 correlates with calcium-mediated regulation of nucleotide metabolism at phosphoribosyl pyrophosphate synthetase von Hupe, Donald J., Behrens, Nancy D., Boltz, Robert

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Method for identifying metalloenzyme inhibitors von HUPE DONALD J, JOHNSON ADAM, DYER RICHARD DENNIS

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Method for treating Alzheimer's disease von HUPE DONALD J, LEVINE HARRY, HASKE TARANEH, SEBOT-LEOPOLD JUDITH, AHN KYUNGHYE, EMMERLING MARK RICHARD, SCHOLTEN JEFFREY DAVID

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