Correlation between in vitro and in vivo concentration–effect relationships of naproxen in rats and healthy volunteers von Huntjens, Dymphy R H, Spalding, David J M, Danhof, Meindert, Della Pasqua, Oscar E

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Population Pharmacokinetic Modeling of JNJ-53718678, a Novel Fusion Inhibitor for the Treatment of Respiratory Syncytial Virus: Results from a Phase I, Double-Blind, Randomized, Pl... von Huntjens, Dymphy R. H., Ouwerkerk-Mahadevan, Sivi, Brochot, Anne, Rusch, Sarah, Stevens, Marita, Verloes, Rene

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Modeling of prolactin response following dopamine D 2 receptor antagonists in rats: can it be translated to clinical dosing? von Taneja, Amit, Vermeulen, An, Huntjens, Dymphy R H, Danhof, Meindert, De Lange, Elizabeth C M, Proost, Johannes H

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A comparison of two semi-mechanistic models for prolactin release and prediction of receptor occupancy following administration of dopamine D2 receptor antagonists in rats von Taneja, Amit, Vermeulen, An, Huntjens, Dymphy R.H., Danhof, Meindert, De Lange, Elizabeth C.M., Proost, Johannes H.

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Modeling of prolactin response following dopamine D2 receptor antagonists in rats: can it be translated to clinical dosing? von Taneja, Amit, Vermeulen, An, Huntjens, Dymphy R. H., Danhof, Meindert, De Lange, Elizabeth C. M., Proost, Johannes H.

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Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo-oxygenase inhibitors von Huntjens, Dymphy R.H, Spalding, David J.M, Danhof, Meindert, Della Pasqua, Oscar E

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Impact of chronic inflammation on the pharmacokinetic–pharmacodynamic relationship of naproxen von Huntjens, Dymphy R.H, Spalding, David J.M, Danhof, Meindert, Della Pasqua, Oscar E

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Summary data of potency and parameter information from semi-mechanistic PKPD modeling of prolactin release following administration of the dopamine D2 receptor antagonists risperid... von Taneja, Amit, Vermeulen, An, Huntjens, Dymphy R.H., Danhof, Meindert, De Lange, Elizabeth C.M., Proost, Johannes H.

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A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations von Yamamoto, Yumi, Välitalo, Pyry A., van den Berg, Dirk-Jan, Hartman, Robin, van den Brink, Willem, Wong, Yin Cheong, Huntjens, Dymphy R., Proost, Johannes H., Vermeulen, An, Krauwinkel, Walter, Bakshi, Suruchi, Aranzana-Climent, Vincent, Marchand, Sandrine, Dahyot-Fizelier, Claire, Couet, William, Danhof, Meindert, van Hasselt, Johan G. C., de Lange, Elizabeth C. M.

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Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach von Yamamoto, Yumi, Välitalo, Pyry A., Wong, Yin Cheong, Huntjens, Dymphy R., Proost, Johannes H., Vermeulen, An, Krauwinkel, Walter, Beukers, Margot W., Kokki, Hannu, Kokki, Merja, Danhof, Meindert, van Hasselt, Johan G.C., de Lange, Elizabeth C.M.

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Predicting Drug Concentration‐Time Profiles in Multiple CNS Compartments Using a Comprehensive Physiologically‐Based Pharmacokinetic Model von Yamamoto, Yumi, Välitalo, Pyry A., Huntjens, Dymphy R., Proost, Johannes H., Vermeulen, An, Krauwinkel, Walter, Beukers, Margot W., van den Berg, Dirk‐Jan, Hartman, Robin, Wong, Yin Cheong, Danhof, Meindert, van Hasselt, John G. C., de Lange, Elizabeth C. M.

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Population Pharmacokinetic Modeling of Tapentadol Extended Release (ER) in Healthy Subjects and Patients with Moderate or Severe Chronic Pain von Huntjens, Dymphy R., Liefaard, Lia C., Nandy, Partha, Drenth, Henk-Jan, Vermeulen, An

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