Inhibition of Cancer Cell Proliferation by PPARγ Is Mediated by a Metabolic Switch that Increases Reactive Oxygen Species Levels von Srivastava, Nishi, Kollipara, Rahul K., Singh, Dinesh K., Sudderth, Jessica, Hu, Zeping, Nguyen, Hien, Wang, Shan, Humphries, Caroline G., Carstens, Ryan, Huffman, Kenneth E., DeBerardinis, Ralph J., Kittler, Ralf

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Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer von Wang, Shan, Kollipara, Rahul K., Srivastava, Nishi, Li, Rui, Ravindranathan, Preethi, Hernandez, Elizabeth, Freeman, Eva, Humphries, Caroline G., Kapur, Payal, Lotan, Yair, Fazli, Ladan, Gleave, Martin E., Plymate, Stephen R., Raj, Ganesh V., Hsieh, Jer-Tsong, Kittler, Ralf

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Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma von Singh, Dinesh K., Kollipara, Rahul K., Vemireddy, Vamsidara, Yang, Xiao-Li, Sun, Yuxiao, Regmi, Nanda, Klingler, Stefan, Hatanpaa, Kimmo J., Raisanen, Jack, Cho, Steve K., Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara, Mashimo, Tomoyuki, Wang, Shan, Humphries, Caroline G., Mickey, Bruce, Maher, Elizabeth A., Zheng, Hongwu, Kim, Ryung S., Kittler, Ralf, Bachoo, Robert M.

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The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer von Wang, Shan, Kollipara, Rahul K, Humphries, Caroline G, Ma, Shi-Hong, Hutchinson, Ryan, Li, Rui, Siddiqui, Javed, Tomlins, Scott A, Raj, Ganesh V, Kittler, Ralf

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Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma von Eskiocak, Banu, McMillan, Elizabeth A, Mendiratta, Saurabh, Kollipara, Rahul K, Zhang, Hailei, Humphries, Caroline G, Wang, Changguang, Garcia-Rodriguez, Jose, Ding, Ming, Zaman, Aubhishek, Rosales, Tracy I, Eskiocak, Ugur, Smith, Michael P, Sudderth, Jessica, Komurov, Kakajan, Deberardinis, Ralph J, Wellbrock, Claudia, Davies, Michael A, Wargo, Jennifer A, Yu, Yonghao, De Brabander, Jef K, Williams, Noelle S, Chin, Lynda, Rizos, Helen, Long, Georgina V, Kittler, Ralf, White, Michael A

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AFAP-120 von Flynn, Daniel C., Koay, Thomas C., Humphries, Caroline G., Guappone, Anne C.

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AFAP-120. A variant form of the Src SH2/SH3-binding partner AFAP-110 is detected in brain and contains a novel internal sequence which binds to a 67-kDa protein von Flynn, D C, Koay, T C, Humphries, C G, Guappone, A C

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Immunoglobulin D switching can occur through homologous recombination in human B cells von WHITE, M. B, WORD, C. J, HUMPHRIES, C. G, BLATTNER, F. R, TUCKER, P. W

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Structure and expression of human germline VH transcripts von BERMAN, J. E, HUMPHRIES, C. G, BARTH, J, ALT, F. W>, TUCKER, P. W

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Immunoglobulin D Switching Can Occur through Homologous Recombination in Human Β Cells von White, Marga B., Word, Charlotte J., Humphries, Caroline G., Blattner, Frederick R., Tucker, Philip W.

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Mendelian randomization of blood lipids for coronary heart disease von Holmes, Michael V, Asselbergs, Folkert W, Palmer, Tom M, Drenos, Fotios, Lanktree, Matthew B, Nelson, Christopher P, Dale, Caroline E, Padmanabhan, Sandosh, Finan, Chris, Swerdlow, Daniel I, Tragante, Vinicius, van Iperen, Erik P A, Sivapalaratnam, Suthesh, Shah, Sonia, Elbers, Clara C, Shah, Tina, Engmann, Jorgen, Giambartolomei, Claudia, White, Jon, Zabaneh, Delilah, Sofat, Reecha, McLachlan, Stela, Doevendans, Pieter A, Balmforth, Anthony J, Hall, Alistair S, North, Kari E, Almoguera, Berta, Hoogeveen, Ron C, Cushman, Mary, Fornage, Myriam, Patel, Sanjay R, Redline, Susan, Siscovick, David S, Tsai, Michael Y, Karczewski, Konrad J, Hofker, Marten H, Verschuren, W Monique, Bots, Michiel L, van der Schouw, Yvonne T, Melander, Olle, Dominiczak, Anna F, Morris, Richard, Ben-Shlomo, Yoav, Price, Jackie, Kumari, Meena, Baumert, Jens, Peters, Annette, Thorand, Barbara, Koenig, Wolfgang, Gaunt, Tom R, Humphries, Steve E, Clarke, Robert, Watkins, Hugh, Farrall, Martin, Wilson, James G, Rich, Stephen S, de Bakker, Paul I W, Lange, Leslie A, Davey Smith, George, Reiner, Alex P, Talmud, Philippa J, Kivimäki, Mika, Lawlor, Debbie A, Dudbridge, Frank, Samani, Nilesh J, Keating, Brendan J, Hingorani, Aroon D, Casas, Juan P

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Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry von Pearsall, Sarah M., Williamson, Stuart C., Humphrey, Sam, Hughes, Ellyn, Morgan, Derrick, García Marqués, Fernando J., Awanis, Griselda, Carroll, Rebecca, Burks, Laura, Shue, Yan Ting, Bermudez, Abel, Frese, Kristopher K., Galvin, Melanie, Carter, Mathew, Priest, Lynsey, Kerr, Alastair, Zhou, Cong, Oliver, Trudy G., Humphries, Jonathan D., Humphries, Martin J., Blackhall, Fiona, Cannell, Ian G., Pitteri, Sharon J., Hannon, Gregory J., Sage, Julien, Dive, Caroline, Simpson, Kathryn L.

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Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease von Zanoni, Paolo, Khetarpal, Sumeet A., Larach, Daniel B., Hancock-Cerutti, William F., Millar, John S., Cuchel, Marina, DerOhannessian, Stephanie, Kontush, Anatol, Surendran, Praveen, Saleheen, Danish, Trompet, Stella, Jukema, J. Wouter, De Craen, Anton, Deloukas, Panos, Sattar, Naveed, Ford, Ian, Packard, Chris, Majumder, Abdullah al Shafi, Alam, Dewan S., Di Angelantonio, Emanuele, Abecasis, Goncalo, Chowdhury, Rajiv, Erdmann, Jeanette, Nordestgaard, Børge G., Nielsen, Sune F., Tybjærg-Hansen, Anne, Schmidt, Ruth Frikke, Kuulasmaa, Kari, Liu, Dajiang J., Perola, Markus, Blankenberg, Stefan, Salomaa, Veikko, Männistö, Satu, Amouyel, Philippe, Arveiler, Dominique, Ferrieres, Jean, Müller-Nurasyid, Martina, Ferrario, Marco, Kee, Frank, Willer, Cristen J., Samani, Nilesh, Schunkert, Heribert, Butterworth, Adam S., Howson, Joanna M. M., Peloso, Gina M., Stitziel, Nathan O., Danesh, John, Kathiresan, Sekar, Rader, Daniel J.

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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci von Reschen, Michael E, Mahajan, Anubha, William Rayner, N, Scott, Laura J, Yengo, Loic, Wahl, Simone, Kestler, Hans, Chheda, Himanshu, Eisele, Lewin, Steinthorsdottir, Valgerdur, Chen, Han, Fuchsberger, Christian, Kwan, Phoenix, Thomsen, Soren K, Rundle, Jana K, van de Bunt, Martijn, Voight, Benjamin F, Abecasis, Gonçalo R, Baldassarre, Damiano, Carey, Jason, Chines, Peter S, Crenshaw, Andrew T, Edkins, Sarah, Eury, Elodie, Fontanillas, Pierre, Franks, Paul W, Gertow, Karl, Groves, Christopher J, Hassinen, Maija, Herder, Christian, Hreidarsson, Astradur B, Jackson, Anne U, Jonsson, Anna, Jørgensen, Marit E, Jørgensen, Torben, Kao, Wen-Hong L, Kerrison, Nicola D, Kinnunen, Leena, Kravic, Jasmina, Langford, Cordelia, Lichtner, Peter, Lindholm, Eero, Lobbens, Stéphane, Luan, Jian'an, Meyer, Julia, Mihailov, Evelin, Mühleisen, Thomas W, Navarro, Carmen, Oskolkov, Nikolay N, Pechlivanis, Sonali, Platou, Carl G P, Rybin, Denis, van der Schouw, Yvonne T, Sennblad, Bengt, Steinbach, Gerald, Storm, Petter, Sun, Qi, Thorand, Barbara, Tikkanen, Emmi, Trakalo, Joseph, Tremoli, Elena, Wood, Andrew R, Zeggini, Eleftheria, Birney, Ewan, Pasquali, Lorenzo, Pankow, James S, van Duijn, Cornelia, Sijbrands, Eric, Hu, Frank B, Thorsteinsdottir, Unnur, Stefansson, Kari, Lakka, Timo A, Rauramaa, Rainer, Stumvoll, Michael, Korpi-Hyövälti, Eeva, Kuusisto, Johanna, Metspalu, Andres, Jöcke, Karl-Heinz, Moebus, Susanne, Bergman, Richard N, Collins, Francis S, Mohlke, Karen L, Koistinen, Heikki, Tuomilehto, Jaakko, Deloukas, Panagiotis, Donnelly, Peter J, Frayling, Timothy M, Sladek, Rob, Froguel, Philippe, Hansen, Torben, Kathiresan, Sekar, Barroso, Inês, Langenberg, Claudia, Wareham, Nicholas J, O'Callaghan, Christopher A, Gloyn, Anna L, Altshuler, David, Boehnke, Michael, Teslovich, Tanya M, Morris, Andrew P

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A No-Prophylaxis Platelet-Transfusion Strategy for Hematologic Cancers von Stanworth, Simon J, Estcourt, Lise J, Powter, Gillian, Kahan, Brennan C, Dyer, Claire, Choo, Louise, Bakrania, Lekha, Llewelyn, Charlotte, Littlewood, Timothy, Soutar, Richard, Norfolk, Derek, Copplestone, Adrian, Smith, Neil, Kerr, Paul, Jones, Gail, Raj, Kavita, Westerman, David A, Szer, Jeffrey, Jackson, Nicholas, Bardy, Peter G, Plews, Dianne, Lyons, Simon, Bielby, Linley, Wood, Erica M, Murphy, Michael F

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Mutations in GDP-Mannose Pyrophosphorylase B Cause Congenital and Limb-Girdle Muscular Dystrophies Associated with Hypoglycosylation of α-Dystroglycan von Carss, Keren J., Stevens, Elizabeth, Foley, A. Reghan, Cirak, Sebahattin, Riemersma, Moniek, Torelli, Silvia, Hoischen, Alexander, Willer, Tobias, van Scherpenzeel, Monique, Moore, Steven A., Messina, Sonia, Bertini, Enrico, Bönnemann, Carsten G., Abdenur, Jose E., Grosmann, Carla M., Kesari, Akanchha, Punetha, Jaya, Quinlivan, Ros, Waddell, Leigh B., Young, Helen K., Wraige, Elizabeth, Yau, Shu, Brodd, Lina, Feng, Lucy, Sewry, Caroline, MacArthur, Daniel G., North, Kathryn N., Hoffman, Eric, Stemple, Derek L., Hurles, Matthew E., van Bokhoven, Hans, Campbell, Kevin P., Lefeber, Dirk J., Lin, Yung-Yao, Muntoni, Francesco

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Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study von Vimaleswaran, Karani S, PhD, Cavadino, Alana, MSc, Berry, Diane J, PhD, Jorde, Rolf, Prof, Dieffenbach, Aida Karina, PhD, Lu, Chen, PhD, Heerspink, Hiddo J Lambers, PhD, Tikkanen, Emmi, PhD, Eriksson, Joel, MD, Wong, Andrew, PhD, Mangino, Massimo, PhD, Jablonski, Kathleen A, PhD, Nolte, Ilja M, PhD, Houston, Denise K, PhD, Ahluwalia, Tarunveer Singh, PhD, van der Most, Peter J, MSc, Pasko, Dorota, MSc, Zgaga, Lina, PhD, Thiering, Elisabeth, MSc, Vitart, Veronique, PhD, Fraser, Ross M, PhD, Huffman, Jennifer E, MSc, de Boer, Rudolf A, Prof, Schöttker, Ben, PhD, Saum, Kai-Uwe, MPH, McCarthy, Mark I, Prof, Dupuis, Josée, Prof, Herzig, Karl-Heinz, Prof, Sebert, Sylvain, PhD, Pouta, Anneli, MD, Laitinen, Jaana, PhD, Kleber, Marcus E, PhD, Navis, Gerjan, Prof, Lorentzon, Mattias, Prof, Jameson, Karen, MSc, Arden, Nigel, Prof, Cooper, Jackie A, MSc, Acharya, Jayshree, PhD, Hardy, Rebecca, Prof, Raitakari, Olli, Prof, Billings, Liana K, MD, Lahti, Jari, PhD, Osmond, Clive, Prof, Penninx, Brenda W, Prof, Rejnmark, Lars, MD, Lohman, Kurt K, MStat, Paternoster, Lavinia, PhD, Stolk, Ronald P, Prof, Hernandez, Dena G, MS, Byberg, Liisa, PhD, Hagström, Emil, MD, Melhus, Håkan, Prof, Ingelsson, Erik, Prof, Mellström, Dan, Prof, Ljunggren, Östen, Prof, Tzoulaki, Ioanna, PhD, McLachlan, Stela, MD, Theodoratou, Evropi, PhD, Tiesler, Carla M T, MSc, Jula, Antti, MD, Navarro, Pau, PhD, Wright, Alan F, Prof, Polasek, Ozren, MD, Wilson, James F, DPhil, Rudan, Igor, Prof, Salomaa, Veikko, Prof, Heinrich, Joachim, PhD, Campbell, Harry, Prof, Price, Jacqueline F, MD, Karlsson, Magnus, Prof, Lind, Lars, MD, Michaëlsson, Karl, Prof, Bandinelli, Stefania, Frayling, Timothy M, Prof, Hartman, Catharina A, PhD, Sørensen, Thorkild I A, Prof, Kritchevsky, Stephen B, Prof, Langdahl, Bente Lomholt, Prof, Eriksson, Johan G, Prof, Florez, Jose C, Prof, Spector, Tim D, Prof, Lehtimäki, Terho, Prof, Kuh, Diana, Prof, Humphries, Steve E, Prof, Cooper, Cyrus, Prof, Ohlsson, Claes, Prof, März, Winfried, Prof, Kumari, Meena, Prof, Kivimaki, Mika, Prof, Wang, Thomas J, Prof, Power, Chris, Prof, Brenner, Hermann, Prof, Grimnes, Guri, MD, van der Harst, Pim, MD, Snieder, Harold, Prof, Hingorani, Aroon D, Prof, Pilz, Stefan, Prof, Whittaker, John C, Prof, Järvelin, Marjo-Riitta, Prof, Hyppönen, Elina, Prof

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Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile von Loos, Ruth J F, Kilpeläinen, Tuomas O, Zillikens, M Carola, Stan ákova, Alena, Finucane, Francis M, Langenberg, Claudia, Zhang, Weihua, Beckmann, Jacques S, Luan, Jian'an, Vandenput, Liesbeth, Styrkarsdottir, Unnur, Zhou, Yanhua, Smith, Albert Vernon, Zhao, Jing-Hua, Amin, Najaf, Shin, So-Youn, Haritunians, Talin, Fu, Mao, Feitosa, Mary F, Kumari, Meena, Halldorsson, Bjarni V, Tikkanen, Emmi, Mangino, Massimo, Hayward, Caroline, Song, Ci, Arnold, Alice M, Aulchenko, Yurii S, Oostra, Ben A, Campbell, Harry, Cupples, L Adrienne, Davis, Kathryn E, Döring, Angela, Eiriksdottir, Gudny, Estrada, Karol, Fernández-Real, José Manuel, Garcia, Melissa, Gieger, Christian, Guiducci, Candace, Hofman, Albert, Isomaa, Bo, Jacobs, Leonie C, Jula, Antti, Karasik, David, Karlsson, Magnus K, Khaw, Kay-Tee, Kim, Lauren J, Kühnel, Brigitte, Kuusisto, Johanna, Liu, Yongmei, Ljunggren, Östen, Lorentzon, Mattias, Luben, Robert N, Mellström, Dan, Mitchell, Braxton D, Mooser, Vincent, Moreno, José Maria, O'Connell, Jeffery R, Pascoe, Laura, Peltonen, Leena, Peral, Belén, Perola, Markus, Salomaa, Veikko, Semple, Robert K, Skaric-Juric, Tatjana, Sigurdsson, Gunnar, Song, Kijoung S, Spector, Timothy D, Syvänen, Ann-Christine, Talmud, Philippa J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Uitterlinden, André G, van Duijn, Cornelia M, Vidal-Puig, Antonio, Wild, Sarah H, Clegg, Deborah J, Schadt, Eric, Wilson, James F, Ripatti, Samuli, Borecki, Ingrid B, Shuldiner, Alan R, Jansson, John-Olov, Kaplan, Robert C, Gudnason, Vilmundur, Harris, Tamara B, Groop, Leif, Kiel, Douglas P, Rivadeneira, Fernando, Walker, Mark, Vollenweider, Peter, Waeber, Gérard, Chambers, John C, Kooner, Jaspal S, Soranzo, Nicole, Hirschhorn, Joel N, Ohlsson, Claes, Wareham, Nicholas J, Speliotes, Elizabeth K, Fox, Caroline S, Laakso, Markku

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SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccination von Cross, Andy, Siggins, Matthew K., Holden, Karl, Liggi, Sonia, Pius, Riinu, Tait, Sarah, Coutts, Audrey, Hafezi, Katarzyna, Bassford, Christopher, Berridge, John, Hartshorn, Stuart, Jacobs, Michael, Kelsey, Michael, Lillie, Patrick, Linnett, Vanessa, Minton, Jane, Mulla, Rohinton, Pintus, Stefania, Shanmuga, Prad, Spittle, Nick, Vincent, Rachel, Wilson, Lawrence, Wiselka, Martin, Young, Peter, Ashworth, Milton, Dunn, Chris, Fisher, Lewis W.S., Murphy, Ellen G, Adrego, R., Aguilar Jimenez, L.A., Ahmed, R., Arnold, H., Bailey, L., Bates, A., Beirne, P., Bisnauthsing, K., Brown, A., Burn, D., Burns, G., Calvelo, E., Carson, G., Carter, P., Cavanagh, J., Channon, K.M., Chinoy, H., Choudhury, G., Clark, D., Cooper, J., Coupland, C., Cox, E., Crisp, P., Crooks, M.G., Deas, C., Dharmagunawardena, R., Dixon, M., Evans, D., Fairman, A., Flynn, M., Ford, A., Gleeson, F., Gorsuch, T., Guillen Guio, B., Harrison, P., Heller, S., Ho, L.P., Humphries, A., Jackson, T., Jezzard, P., Jones, H., Kaltsakas, G., Keenan, N., Klenerman, P., Linford, S., Mallison, G., March, K., Mariveles, M., Martineau, A., Maskell, N., Newell, H., Ostermann, M., Pendlebury, J., Peto, T., Portukhay, S., Price, A., Reed, A., Rostron, A., Roy, K., Sanderson, A., Selby, N., Sharpe, C., Smith, J., Solstice, A.R., Teixeira, J., Tobin, M., West, S., Wild, J., Williams, N., Willoughby, J., Wright, L., Wright, S.

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A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type von Chin, E R, Olson, E N, Richardson, J A, Yang, Q, Humphries, C, Shelton, J M, Wu, H, Zhu, W, Bassel-Duby, R, Williams, R S

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