Synthesis, biological evaluation, structural–activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators von Barrett, Irene, Meegan, Mary J., Hughes, Rosario B., Carr, Miriam, Knox, Andrew J.S., Artemenko, Natalia, Golfis, Georgia, Zisterer, Daniela M., Lloyd, David G.

Volltext

Benzoxepin-Derived Estrogen Receptor Modulators:  A Novel Molecular Scaffold for the Estrogen Receptor von Lloyd, David G, Hughes, Rosario B, Zisterer, Daniela M, Williams, D. Clive, Fattorusso, Caterina, Catalanotti, Bruno, Campiani, Giuseppe, Meegan, Mary J

Volltext

Flexible Estrogen Receptor Modulators:  Design, Synthesis, and Antagonistic Effects in Human MCF-7 Breast Cancer Cells von Meegan, Mary J, Hughes, Rosario B, Lloyd, David G, Williams, D. Clive, Zisterer, Daniela M

Volltext

ChemInform Abstract: Flexible Estrogen Receptor Modulators: Design, Synthesis, and Antagonistic Effects in Human MCF-7 Breast Cancer Cells von Meegan, Mary J., Hughes, Rosario B., Lloyd, David G., Williams, D. Clive, Zisterer, Daniela M.

Volltext

10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer von Hamdy, Freddie C, Donovan, Jenny L, Lane, J. Athene, Mason, Malcolm, Metcalfe, Chris, Holding, Peter, Davis, Michael, Peters, Tim J, Turner, Emma L, Martin, Richard M, Oxley, Jon, Robinson, Mary, Staffurth, John, Walsh, Eleanor, Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Kockelbergh, Roger, Kynaston, Howard, Paul, Alan, Powell, Philip, Prescott, Stephen, Rosario, Derek J, Rowe, Edward, Neal, David E

Volltext

Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer von Hamdy, Freddie C., Donovan, Jenny L., Lane, J. Athene, Metcalfe, Chris, Davis, Michael, Turner, Emma L., Martin, Richard M., Young, Grace J., Walsh, Eleanor I., Bryant, Richard J., Bollina, Prasad, Doble, Andrew, Doherty, Alan, Gillatt, David, Gnanapragasam, Vincent, Hughes, Owen, Kockelbergh, Roger, Kynaston, Howard, Paul, Alan, Paez, Edgar, Powell, Philip, Rosario, Derek J., Rowe, Edward, Mason, Malcolm, Catto, James W.F., Peters, Tim J., Oxley, Jon, Williams, Naomi J., Staffurth, John, Neal, David E.

Volltext

Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer von Donovan, Jenny L, Hamdy, Freddie C, Lane, J. Athene, Mason, Malcolm, Metcalfe, Chris, Walsh, Eleanor, Blazeby, Jane M, Peters, Tim J, Holding, Peter, Bonnington, Susan, Lennon, Teresa, Bradshaw, Lynne, Cooper, Deborah, Herbert, Phillipa, Howson, Joanne, Jones, Amanda, Lyons, Norma, Salter, Elizabeth, Thompson, Pauline, Tidball, Sarah, Blaikie, Jan, Gray, Catherine, Bollina, Prasad, Catto, James, Doble, Andrew, Doherty, Alan, Gillatt, David, Kockelbergh, Roger, Kynaston, Howard, Paul, Alan, Powell, Philip, Prescott, Stephen, Rosario, Derek J, Rowe, Edward, Davis, Michael, Turner, Emma L, Martin, Richard M, Neal, David E

Volltext

Clinicopathologic Features and Prognostic Impact of Lymph Node Involvement in Patients With Breast Implant-associated Anaplastic Large Cell Lymphoma von Ferrufino-Schmidt, Maria C, Medeiros, L Jeffrey, Liu, Hui, Clemens, Mark W, Hunt, Kelly K, Laurent, Camille, Lofts, Julian, Amin, Mitual B, Ming Chai, Siaw, Morine, Angela, Di Napoli, Arianna, Dogan, Ahmet, Parkash, Vinita, Bhagat, Govind, Tritz, Denise, Quesada, Andres E, Pina-Oviedo, Sergio, Hu, Qinlong, Garcia-Gomez, Francisco J, Jose Borrero, Juan, Horna, Pedro, Thakral, Beenu, Narbaitz, Marina, Hughes, R Condon, Yang, Li-Jun, Fromm, Jonathan R, Wu, David, Zhang, Da, Sohani, Aliyah R, Hunt, John, Vadlamani, Indira U, Morgan, Elizabeth A, Ferry, Judith A, Sziget, Reka, C. Tardio, Juan, Granados, Rosario, Dertinger, Susanne, Offner, Felix A, Pircher, Andreas, Hosry, Jeff, Young, Ken H, Miranda, Roberto N

Volltext

Pre-diagnostic copper and zinc biomarkers and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort von Stepien, Magdalena, Jenab, Mazda, Freisling, Heinz, Becker, Niels-Peter, Czuban, Magdalena, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Boutron-Ruault, Marie-Christine, Mancini, Francesca Romana, Savoye, Isabelle, Katzke, Verena, Kühn, Tilman, Boeing, Heiner, Iqbal, Khalid, Trichopoulou, Antonia, Bamia, Christina, Orfanos, Philippos, Palli, Domenico, Sieri, Sabina, Tumino, Rosario, Naccarati, Alessio, Panico, Salvatore, Bueno-de-Mesquita, H B As, Peeters, Petra H, Weiderpass, Elisabete, Merino, Susana, Jakszyn, Paula, Sanchez, Maria-Jose, Dorronsoro, Miren, Huerta, José María, Barricarte, Aurelio, Boden, Stina, van Guelpen, Behany, Wareham, Nick, Khaw, Kay-Tee, Bradbury, Kathryn E, Cross, Amanda J, Schomburg, Lutz, Hughes, David J

Volltext

PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena von Hughes, Shannon K, Oudin, Madeleine J, Tadros, Jenny, Neil, Jason, Del Rosario, Amanda, Joughin, Brian A, Ritsma, Laila, Wyckoff, Jeff, Vasile, Eliza, Eddy, Robert, Philippar, Ulrike, Lussiez, Alisha, Condeelis, John S, van Rheenen, Jacco, White, Forest, Lauffenburger, Douglas A, Gertler, Frank B

Volltext

Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study von Aglago, Elom K., Cross, Amanda J., Riboli, Elio, Fedirko, Veronika, Hughes, David J., Fournier, Agnes, Jakszyn, Paula, Freisling, Heinz, Gunter, Marc J., Dahm, Christina C., Overvad, Kim, Tjønneland, Anne, Kyrø, Cecilie, Boutron-Ruault, Marie-Christine, Rothwell, Joseph A., Severi, Gianluca, Katzke, Verena, Srour, Bernard, Schulze, Matthias B., Wittenbecher, Clemens, Palli, Domenico, Sieri, Sabina, Pasanisi, Fabrizio, Tumino, Rosario, Ricceri, Fulvio, Bueno-de-Mesquita, Bas, Derksen, Jeroen W. G., Skeie, Guri, Jensen, Torill Enget, Lukic, Marko, Sánchez, Maria-Jose, Amiano, Pilar, Colorado-Yohar, Sandra, Barricarte, Aurelio, Ericson, Ulrika, van Guelpen, Bethany, Papier, Keren, Knuppel, Anika, Casagrande, Corinne, Huybrechts, Inge, Heath, Alicia K., Tsilidis, Konstantinos K., Jenab, Mazda

Volltext

Pre‐diagnostic plasma advanced glycation end‐products and soluble receptor for advanced glycation end‐products and mortality in colorectal cancer patients von Li, Jinze, Roshelli Baker, Jacqueline, Aglago, Elom K., Zhao, Zhiwei, Jiao, Li, Freisling, Heinz, Hughes, David J., Eriksen, Anne Kirstine, Tjønneland, Anne, Severi, Gianluca, Katzke, Verena, Kaaks, Rudolf, Schulze, Matthias B., Masala, Giovanna, Pala, Valeria, Pasanisi, Fabrizio, Tumino, Rosario, Padroni, Lisa, Vermeulen, Roel C. H., Gram, Inger T., Braaten, Tonje, Jakszyn, Paula Gabriela, Sánchez, Maria‐José, Gómez‐Gómez, Jesús‐Humberto, Moreno‐Iribas, Conchi, Amiano, Pilar, Papier, Keren, Weiderpass, Elisabete, Huybrechts, Inge, Heath, Alicia K., Schalkwijk, Casper, Jenab, Mazda, Fedirko, Veronika

Volltext

Efficacy and Safety of COVID-19 Convalescent Plasma in Hospitalized Patients: A Randomized Clinical Trial von Ortigoza, Mila B, Yoon, Hyunah, Goldfeld, Keith S, Troxel, Andrea B, Daily, Johanna P, Wu, Yinxiang, Li, Yi, Wu, Danni, Cobb, Gia F, Baptiste, Gillian, O’Keeffe, Mary, Corpuz, Marilou O, Ostrosky-Zeichner, Luis, Amin, Amee, Zacharioudakis, Ioannis M, Jayaweera, Dushyantha T, Wu, Yanyun, Philley, Julie V, Devine, Megan S, Desruisseaux, Mahalia S, Santin, Alessandro D, Anjan, Shweta, Mathew, Reeba, Patel, Bela, Nigo, Masayuki, Upadhyay, Rabi, Kupferman, Tania, Dentino, Andrew N, Nanchal, Rahul, Merlo, Christian A, Hager, David N, Chandran, Kartik, Lai, Jonathan R, Rivera, Johanna, Bikash, Chowdhury R, Lasso, Gorka, Hilbert, Timothy P, Paroder, Monika, Asencio, Andrea A, Liu, Mengling, Petkova, Eva, Bragat, Alexander, Shaker, Reza, McPherson, David D, Sacco, Ralph L, Keller, Marla J, Grudzen, Corita R, Hochman, Judith S, Pirofski, Liise-anne, Parameswaran, Lalitha, Corcoran, Anthony T, Rohatgi, Abhinav, Wronska, Marta W, Wu, Xinyuan, Srinivasan, Ranjini, Deng, Fang-Ming, Filardo, Thomas D, Pendse, Jay, Blaser, Simone B, Whyte, Olga, Gallagher, Jacqueline M, Thomas, Ololade E, Ramos, Danibel, Sturm-Reganato, Caroline L, Fong, Charlotte C, Daus, Ivy M, Payoen, Arianne Gisselle, Chiofolo, Joseph T, Friedman, Mark T, Wu, Ding Wen, Jacobson, Jessica L, Schneider, Jeffrey G, Sarwar, Uzma N, Wang, Henry E, Huebinger, Ryan M, Dronavalli, Goutham, Bai, Yu, Grimes, Carolyn Z, Eldin, Karen W, Umana, Virginia E, Martin, Jessica G, Heath, Timothy R, Bello, Fatimah O, Ransford, Daru Lane, Laurent-Rolle, Maudry, Shenoi, Sheela V, Akide-Ndunge, Oscar Bate, Thapa, Bipin, Peterson, Jennifer L, Knauf, Kelly, Patel, Shivani U, Cheney, Laura L, Tormey, Christopher A, Hendrickson, Jeanne E

Volltext

Ten-year Mortality, Disease Progression, and Treatment-related Side Effects in Men with Localised Prostate Cancer from the ProtecT Randomised Controlled Trial According to Treatmen... von Neal, David E., Donovan, Jenny L., Martin, Richard M., Peters, Tim. J., Bollina, Prasad, Doherty, Alan, Gillatt, David, Hughes, Owen, Paez, Edgar, Rosario, Derek J., Rowe, Edward, Staffurth, John, Altman, Doug G., Hamdy, Freddie C., Lane, J. Athene, Hughes, Owen, Prescott, Stephen, Rowe, Edward, Aning, Jonathan, McNeill, Alan, Schwaibold, Hartwig, Herbert, Phillipa, Jones, Amanda, Lennon, Teresa, Lyons, Norma, Thompson, Pauline, Gray, Catherine, Askew, Sarah, Brain, Carole, Dark, Susan, Davis, Gill, Denizot, Jane, Dewhurst, Elspeth, Emmerson, Ingrid, Grant, Alison, Hawkins, Sarah, Kilner, Sue, Marshall, Fiona, Mellen, Louise, Pisa, Anna, Robson, Lindsay, Samuel, Nikki, Sharkey, Irene, Smith, Donna, Taylor, Helen, Trewick, Nicola, Woodhouse, Colin, Ferguson, Catherine, Graham, John, Howard, Grahame, Law, Alastair, Russell, Simon, Thanvi, Narottam, Oxley, Jon, Robinson, Mary, Bhattarai, Selina, Deshmukh, Neeta, Griffiths, David, Grigor, Ken, Ash, Dominic, Bolton, Steven, Conway, John, Lamb, Susan, Lawrence, Gill, Lewis, Geraint, McQueen, Alison, Moore, Rollo, Potterton, Janet, Showler, Helen, Slade, Stephen, Townley, John, Wills, Lucy, Davies, Linda, Khazragui, Hanan, Noble, Sian, Bellis-Sheldon, Elizabeth, Bowtell, Joanne, Clark, Rebecca, Currer, Rosemary, Delaney, Gill, Farmer, Rebecca, Haddow, Jean, Halpin, Susan, Hattrick, Barbara, Liddiatt, Tanya, Moore, Susan, Wilkins, Zoe, Williams, Sharon, Wilson, Andrea, Zietman, Anthony, Williams, Naomi, Toole, Jessica, Bell, Lindsey, Mauree, Jainnee, Ashby, Deborah, Cowan, Richard, Mellon, Killian, N’Dow, James, Schröder, Fritz, Roberts, Tracy

Volltext

Circulating copper and zinc levels and risk of hepatobiliary cancers in Europeans von Stepien, Magdalena, Hughes, David J, Hybsier, Sandra, Bamia, Christina, Tjønneland, Anne, Overvad, Kim, Affret, Aurélie, His, Mathilde, Boutron-Ruault, Marie-Christine, Katzke, Verena, Kühn, Tilman, Aleksandrova, Krasimira, Trichopoulou, Antonia, Lagiou, Pagona, Orfanos, Phlippos, Palli, Domenico, Sieri, Sabina, Tumino, Rosario, Ricceri, Fulvio, Panico, Salvatore, Bueno-de-Mesquita, H B(as), Peeters, Petra H, Weiderpass, Elisabete, Lasheras, Cristina, Bonet Bonet, Catalina, Molina-Portillo, Elena, Dorronsoro, Miren, Huerta, José María, Barricarte, Aurelio, Ohlsson, Bodil, Sjöberg, Klas, Werner, Mårten, Shungin, Dmitry, Wareham, Nick, Khaw, Kay-Tee, Travis, Ruth C, Freisling, Heinz, Cross, Amanda J, Schomburg, Lutz, Jenab, Mazda

Volltext

Prediagnostic serum calcium concentrations and risk of colorectal cancer development in 2 large European prospective cohorts von Karavasiloglou, Nena, Hughes, David J., Murphy, Neil, Schomburg, Lutz, Sun, Qian, Seher, Vartiter, Rohrmann, Sabine, Weiderpass, Elisabete, Tjønneland, Anne, Olsen, Anja, Overvad, Kim, Boutron-Ruault, Marie-Christine, Mancini, Francesca Romana, Mahamat-Saleh, Yahya, Kaaks, Rudolf, Kuhn, Tilman, Schulze, Matthias B., Tumino, Rosario, Panico, Salvatore, Masala, Giovanna, Pala, Valeria, Sacerdote, Carlotta, Derksen, Jeroen W.G., Skeie, Guri, Hjartåker, Anette, Lasheras, Cristina, Agudo, Antonio, Sánchez, Maria-José, Chirlaque, Maria-Dolores, Ardanaz, Eva, Amiano, Pilar, Van Guelpen, Bethany, Gylling, Björn, Bradbury, Kathryn E., Papier, Keren, Freisling, Heinz, Aglago, Elom K., Cross, Amanda J., Riboli, Elio, Aune, Dagfinn, Gunter, Marc J., Jenab, Mazda

Volltext

Pasireotide can induce sustained decreases in urinary cortisol and provide clinical benefit in patients with Cushing’s disease: results from an open-ended, open-label extension tri... von Schopohl, Jochen, Gu, Feng, Rubens, Robert, Van Gaal, Luc, Bertherat, Jérôme, Ligueros-Saylan, Monica, Trovato, Andrew, Hughes, Gareth, Salgado, Luiz R., Boscaro, Marco, Pivonello, Rosario

Volltext

The common marmoset genome provides insight into primate biology and evolution von Worley, Kim C, Warren, Wesley C, Rogers, Jeffrey, Locke, Devin, Muzny, Donna M, Mardis, Elaine R, Weinstock, George M, Tardif, Suzette D, Aagaard, Kjersti M, Archidiacono, Nicoletta, Wang, Qing, Warner, Crystal M, Wildman, Derek E, Witherspoon, David J, Wright, Rita A, Wu, Yuanqing, Xiao, Weimin, Xing, Jinchuan, Zhu, Baoli, Rayan, Nirmala Arul, Gibbs, Richard A, Wilson, Richard K, Batzer, Mark A, Beal, Kathryn, Brejova, Brona, Capozzi, Oronzo, Capuano, Saverio B, Casola, Claudio, Chandrabose, Mimi M, Dao, Marvin Diep, de Jong, Pieter J, del Rosario, Ricardo Cruz-Herrera, Delehaunty, Kkim D, Dinh, Huyen H, Eichler, Evan E, Fitzgerald, Stephen, Flicek, Paul, Fowler, R Gerald, Fronick, Catrina, Fulton, Lucinda A, Fulton, Robert S, Gabisi, Ramatu Ayiesha, Gerlach, Daniel, Graves, Tina A, Gunaratne, Preethi H, Hahn, Matthew W, Haig, David, Han, Yi, Harris, R Alan, Herrero, Javier, Hillier, LaDdeana W, Hubley, Robert, Jhangiani, Shalini N, Jorde, Lynn B, Joshi, Vandita, Karakor, Emre, Konkel, Miriam K, Kovar, Christie L, Kriventseva, Evgenia V, Lee, Sandra L, Liu, Yih-shin, Lopez, John, Lopez-Otin, Carlos, Mansfield, Keith G, Marques-Bonet, Tomas, Minx, Patrick, Misceo, Doriana, Moncrieff, J Scott, Morgan, Margaret B, Nazareth, Lynne V, Newsham, Irene, Nguyen, Ngoc Bich, Okwuonu, Geoffrey O, Prabhakar, Shyam, Pu, Ling-Ling, Quesada, Victor, Ranck, Megan C, Raney, Brian J, Deiros, David Rio, Rocchi, Mariano, Rodriguez, David, Ross, Corinna, Ruffier, Magali, Ruiz, San Juana, Sajjadian, Saba, Santibanez, Jireh, Schrider, Daniel R, Searle, Steve, Skaletsky, Helen, Soibam, Benjamin, Smit, Arian F A, Tennakoon, Jayantha B, Tomaska, Lubomir, Ullmer, Brygg, Vejnar, Charles E, Ventura, Mario, Vilella, Albert J, Vinar, Tomas, Vogel, Jan-Hinnerk, Walker, Jerilyn A

Volltext

Prospective evaluation of antibody response to Streptococcus gallolyticus and risk of colorectal cancer von Butt, Julia, Jenab, Mazda, Willhauck‐Fleckenstein, Martina, Michel, Angelika, Pawlita, Michael, Kyrø, Cecilie, Tjønneland, Anne, Boutron‐Ruault, Marie‐Christine, Carbonnel, Franck, Severi, Gianluca, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Trichopoulou, Antonia, la Vecchia, Carlo, Karakatsani, Anna, Panico, Salvatore, Tumino, Rosario, Agnoli, Claudia, Palli, Domenico, Sacerdote, Carlotta, Bueno‐de‐Mesquita, H. B(as), Weiderpass, Elisabete, Sánchez, Maria‐José, Bonet Bonet, Catalina, Huerta, José María, Ardanaz, Eva, Bradbury, Kathryn, Gunter, Marc, Murphy, Neil, Freisling, Heinz, Riboli, Elio, Tsilidis, Kostas, Aune, Dagfinn, Waterboer, Tim, Hughes, David J.

Volltext

Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study von Aglago, Elom K, Schalkwijk, Casper G, Freisling, Heinz, Fedirko, Veronika, Hughes, David J, Jiao, Li, Dahm, Christina C, Olsen, Anja, Tjønneland, Anne, Katzke, Verena, Johnson, Theron, Schulze, Matthias B, Aleksandrova, Krasimira, Masala, Giovanna, Sieri, Sabina, Simeon, Vittorio, Tumino, Rosario, Macciotta, Alessandra, Bueno-de-Mesquita, Bas, Skeie, Guri, Gram, Inger Torhild, Sandanger, Torkjel, Jakszyn, Paula, Sánchez, Maria-Jose, Amiano, Pilar, Colorado-Yohar, Sandra M, Gurrea, Aurelio Barricarte, Perez-Cornago, Aurora, Mayén, Ana-Lucia, Weiderpass, Elisabete, Gunter, Marc J, Heath, Alicia K, Jenab, Mazda

Volltext