p53 Mediates Colistin-Induced Autophagy and Apoptosis in PC-12 Cells von Zhang, Ling, Xie, Daoyuan, Chen, Xueping, Hughes, Maria L R, Jiang, Guozheng, Lu, Ziyin, Xia, Chunli, Li, Li, Wang, Jinli, Xu, Wei, Sun, Yuan, Li, Rui, Wang, Rui, Qian, Feng, Li, Jian, Li, Jichang

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GABAergic striatal neurons exhibit caspase-independent, mitochondrially mediated programmed cell death von Diwakarla, Shanti, Mercer, Linda D, Kardashsyan, Liubov, Chu, Percy W.Y, Shin, Yea Seul, Lau, Chew L, Hughes, Maria L.R, Nagley, Phillip, Beart, Philip M

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Stereoselective synthesis of (.+-.)-indolizidines 167B, 205A, and 207A. Enantioselective synthesis of (-)-indolizidine 209B von Holmes, Andrew B, Smith, Adrian L, Williams, Simon F, Hughes, Leslie R, Lidert, Zev, Swithenbank, Colin

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Quinazoline antifolate thymidylate synthase inhibitors: heterocyclic benzoyl ring modifications von Marsham, Peter R, Hughes, Leslie R, Jackman, Ann L, Hayter, Anthony J, Oldfield, John, Wardleworth, J. Michael, Bishop, Joel A. M, O'Connor, Brigid M, Calvert, A. Hilary

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Nonsteroidal progestins and antiprogestins related to flutamide von Dukes, Michael, Furr, Barrington J.A, Hughes, Leslie R, Tucker, Howard, Woodburn, James R

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Quinazoline Antifolate Thymidylate Synthase Inhibitors: Replacement of Glutamic Acid in the C2-Methyl Series von Marsham, Peter R, Jackman, Ann L, Barker, Andrew J, Boyle, F. Thomas, Pegg, Stephen J, Wardleworth, J. Michael, Kimbell, Rosemary, O'Connor, Brigid M, Calvert, A. Hilary, Hughes, Leslie R

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Syntheses and thymidylate synthase inhibitory activity of the poly-.gamma.-glutamyl conjugates of N-[5-[N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl... von Bisset, Graham M. F, Pawelczak, Krzysztof, Jackman, Ann L, Calvert, A. Hilary, Hughes, Leslie R

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Quinazoline antifolate thymidylate synthase inhibitors: alkyl, substituted alkyl, and aryl substituents in the C2 position von Hughes, L R, Jackman, A L, Oldfield, J, Smith, R C, Burrows, K D, Marsham, P R, Bishop, J A, Jones, T R, O'Connor, B M, Calvert, A H

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Quinazoline-antifolate thymidylate synthase inhibitors: benzoyl ring modifications in the C2-methyl series von Marsham, Peter R, Jackman, Ann L, Oldfield, John, Hughes, Leslie R, Thornton, Timothy J, Bisset, Graham M. F, O'Connor, Brigid M, Bishop, Joel A. M, Calvert, A. Hilary

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Wittig reactions on unprotected aldohexoses: Formation of optically active tetrahydrofurans and tetrahydropyrans von Davidson, Alan.H., Hughes, Leslie R., Qureshi, Sheila S., Wright, Brian

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Quinazoline antifolate thymidylate synthase inhibitors: bridge modifications and conformationally restricted analogs in the C2-methyl series von Marsham, Peter R, Jackman, Ann L, Hayter, Anthony J, Daw, Melanie R, Snowden, Jayne L, O'Connor, Brigid M, Bishop, Joel A. M, Calvert, A. Hilary, Hughes, Leslie R

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Quinazoline antifolate thymidylate synthase inhibitors: nitrogen, oxygen, sulfur, and chlorine substituents in the C2 position von Marsham, Peter R, Chambers, Paula, Hayter, Anthony J, Hughes, Leslie R, Jackman, Ann L, O'Connor, Breda M, Bishop, Joel A. M, Calvert, A. Hilary

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The renal effects of N10-propargyl-5,8-dideazafolic acid (CB3717) and a non-nephrotoxic analogue ICI D1694, in mice von Jodrell, DI, Newell, DR, Morgan, SE, Clinton, S, Bensted, JPM, Hughes, LR, Calvert, AH

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Synthetic studies on ambruticin: Determination of the absolute stereochemistry by a chiral synthesis of the cyclopropane ring von Barnes, Nigel J., Davidson, Alan H., Hughes, Leslie R., Procter, Garry, Rajcoomar, Veedianand

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Biomimetic polyene cyclizations. A comparison of the phenylacetylenic and styryl terminators in influencing the stereoselectivity of processes leading to steroidal products von Johnson, William S., Hughes, Leslie R., Carlson, Janet L.

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Participation of the allylsilane group as a terminator of biomimetic polyene cyclizations to form steroid-like products von Hughes, Leslie R., Schmid, Rudolf, Johnson, William S.

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On maximum-distance-separable convolutional codes (Corresp.) von Justesen, J., Hughes, L.

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Lactation and Genital Involution Effects of a New Low-dose Oral Contraceptive on Breast-feeding Mothers and their Infants von MILLER, GEORGE H., HUGHES, LOWELL R.

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Biomimetic polyene cyclizations. Participation of the phenylacetylenic group as a terminator and the formation of C/D cis steroidal products von Johnson, William S., Hughes, Leslie R., Kloek, James A., Niem, Tony, Shenvi, Ashok

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Thymidylate synthase: A target for anticancer drug design von Harrap, K.R., Jackman, A.L., Newell, D.R., Taylor, G.A., Hughes, L.R., Calvert, A.H.

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