Cysteine Toxicity Drives Age-Related Mitochondrial Decline by Altering Iron Homeostasis von Hughes, Casey E., Coody, Troy K., Jeong, Mi-Young, Berg, Jordan A., Winge, Dennis R., Hughes, Adam L.

Volltext

A Smoothened-Evc2 Complex Transduces the Hedgehog Signal at Primary Cilia von Dorn, Karolin V., Hughes, Casey E., Rohatgi, Rajat

Volltext

Selective sorting and destruction of mitochondrial membrane proteins in aged yeast von Hughes, Adam L, Hughes, Casey E, Henderson, Kiersten A, Yazvenko, Nina, Gottschling, Daniel E

Volltext

EFCAB7 and IQCE Regulate Hedgehog Signaling by Tethering the EVC-EVC2 Complex to the Base of Primary Cilia von Pusapati, Ganesh V., Hughes, Casey E., Dorn, Karolin V., Zhang, Dapeng, Sugianto, Priscilla, Aravind, L., Rohatgi, Rajat

Volltext

Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips von Earhart, Christopher M, Hughes, Casey E, Gaster, Richard S, Ooi, Chin Chun, Wilson, Robert J, Zhou, Lisa Y, Humke, Eric W, Xu, Lingyun, Wong, Dawson J, Willingham, Stephen B, Schwartz, Erich J, Weissman, Irving L, Jeffrey, Stefanie S, Neal, Joel W, Rohatgi, Rajat, Wakelee, Heather A, Wang, Shan X

Volltext

Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms von Ouyang, Yeyun, Jeong, Mi-Young, Cunningham, Corey N, Berg, Jordan A, Toshniwal, Ashish G, Hughes, Casey E, Seiler, Kristina, Van Vranken, Jonathan G, Cluntun, Ahmad A, Lam, Geanette, Winter, Jacob M, Akdogan, Emel, Dove, Katja K, Nowinski, Sara M, West, Matthew, Odorizzi, Greg, Gygi, Steven P, Dunn, Cory D, Winge, Dennis R, Rutter, Jared

Volltext

Glutaminyl‐tRNA Synthetase from Pseudomonas aeruginosa: Characterization, structure, and development as a screening platform von Escamilla, Yaritza, Hughes, Casey A., Abendroth, Jan, Dranow, David M., Balboa, Samantha, Dean, Frank B., Bullard, James M.

Volltext

Two Forms of Tyrosyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization and Discovery of Inhibitory Compounds von Hughes, Casey A., Gorabi, Varesh, Escamilla, Yaritza, Dean, Frank B., Bullard, James M.

Volltext

Flow Homogenization Enables a Massively Parallel Fluidic Design for High‐Throughput and Multiplexed Cell Isolation von Ooi, Chinchun, Earhart, Christopher M., Hughes, Casey E., Lee, Jung‐Rok, Wong, Dawson J., Wilson, Robert J., Rohatgi, Rajat, Wang, Shan X.

Volltext

Characterization of the Tyrosyl‐S and Tyrosyl‐Z tRNA Synthetases from Pseudomonas aeruginosa and Discovery of Inhibitors von Bullard, James M., Hughes, Casey A., Escamilla, Yaritza

Volltext

Identification of Inhibitors of Glutaminyl‐tRNA synthetase from Pseudomonas aeruginosa von Escamilla, Yaritza, Hughes, Casey A, Bullard, James M

Volltext

Cloning and Characterization of the Tyrosyl‐S and Tyrosyl‐Z tRNA Synthetases from Pseudomonas aeruginosa von Hughes, Casey A, Gorabi, Varesh, Bullard, James M

Volltext

Crosslinked hydrogels for tympanic membrane repair von Park, Albert H., Hughes, Casey W., Jackson, Adrienne, Hunter, Lisa, McGill, Lawrence, Simonsen, Sara Ellis, Alder, Stephen C., Shu, Xiao Zheng, Prestwich, Glenn D.

Volltext

Development of Glutaminyl‐tRNA Synthetase from Pseudomonas aeruginosa as a Platform to Screen for Inhibitors of Protein Synthesis von Escamilla, Yaritza, Hughes, Casey, Hu, Yanmei, Bullard, James M

Volltext

Development of a Natural Protein Synthesis System from Pseudomonas aeruginosa von Hughes, Casey, Escamilla, Yaritza, Hu, Yanmei, Bullard, James M

Volltext

Rational Design of an Antimicrobial Peptide Based on Structural Insight into the Interaction of Pseudomonas aeruginosa Initiation Factor 1 with Its Cognate 30S Ribosomal Subunit von Valdez, Nicolette, Hughes, Casey, Palmer, Stephanie O, Sepulveda, Alyssa, Dean, Frank B, Escamilla, Yaritza, Bullard, James M, Zhang, Yonghong

Volltext

Abstract PR03: Genome-wide screens for Wnt signaling in human haploid cells von Lebensohn, Andres, Hughes, Casey, Marceau, Caleb, Rohatgi, Rajat, Carette, Jan

Volltext

Design, Synthesis and Microbiological Evaluation of Novel Compounds as Potential Staphylococcus aureus Phenylalanine tRNA Synthetase Inhibitors von Elbaramawi, Samar S, Hughes, Casey, Richards, Jennifer, Gupta, Arya, Ibrahim, Samy M, Lashine, El-Sayed M, El-Sadek, Mohamed E, O'Neill, Alex J, Wootton, Mandy, Bullard, James M, Simons, Claire

Volltext

A Novel Crosslinkable Hydrogel for Tympanic Membrane Perforation Repair von Park, Albert H., Hughes, Casey, Prestwich, Glenn D., Hunter, Lisa, McGill, Larry

Volltext

Environmental and Physiological Factors Affecting High-Throughput Measurements of Bacterial Growth von Atolia, Esha, Cesar, Spencer, Arjes, Heidi A, Rajendram, Manohary, Shi, Handuo, Knapp, Benjamin D, Khare, Somya, Aranda-Díaz, Andrés, Lenski, Richard E, Huang, Kerwyn Casey

Volltext