Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor–Prolyl Hydroxylase Inhibitor for Anemia von Ariazi, Jennifer L., Duffy, Kevin J., Adams, David F., Fitch, Duke M., Luo, Lusong, Pappalardi, Melissa, Biju, Mangatt, DiFilippo, Erin Hugger, Shaw, Tony, Wiggall, Ken, Erickson-Miller, Connie

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Effects of Poly(ethylene glycol) on Efflux Transporter Activity in Caco‐2 Cell Monolayers von Hugger, Erin D., Audus, Kenneth L., Borchardt, Ronald T.

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Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885 von KING, Alastair J, PATRICK, Denis R, HUGGER, Erin, LIFU WANG, KARRETH, Florian, LOUGHEED, Julie C, LEE, Jae, CHAU, David, STOUT, Thomas J, MAY, Earl W, ROMINGER, Cynthia M, SCHABER, Michael D, BATORSKY, Roberta S, LUSONG LUO, LAKDAWALA, Ami S, ADAMS, Jerry L, CONTRACTOR, Rooja G, SMALLEY, Keiran S. M, HERLYN, Meenhard, MORRISSEY, Michael M, TUVESON, David A, HUANG, Pearl S, HO, Maureen L, DO, Hieu T, SHU YUN ZHANG, KUMAR, Rakesh, RUSNAK, David W, TAKLE, Andrew K, WILSON, David M

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A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P‐glycoprotein activity in vitro von Hugger, Erin D., Novak, Barbara L., Burton, Philip S., Audus, Kenneth L., Borchardt, Ronald T.

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Novel ATP-Competitive Kinesin Spindle Protein Inhibitors von Parrish, Cynthia A, Adams, Nicholas D, Auger, Kurt R, Burgess, Joelle L, Carson, Jeffrey D, Chaudhari, Amita M, Copeland, Robert A, Diamond, Melody A, Donatelli, Carla A, Duffy, Kevin J, Faucette, Leo F, Finer, Jeffrey T, Huffman, William F, Hugger, Erin D, Jackson, Jeffrey R, Knight, Steven D, Luo, Lusong, Moore, Michael L, Newlander, Ken A, Ridgers, Lance H, Sakowicz, Roman, Shaw, Antony N, Sung, Chiu-Mei M, Sutton, David, Wood, Kenneth W, Zhang, Shu-Yun, Zimmerman, Michael N, Dhanak, Dashyant

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Automated Analysis of Polyethylene Glycol-Induced Inhibition of P-Glycoprotein Activity In Vitro von Hugger, Erin D., Cole, Clayton J., Raub, Thomas J., Burton, Philip S., Borchardt, Ronald T.

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A coumarin-based prodrug strategy to improve the oral absorption of RGD peptidomimetics von Wang, Wei, Camenisch, Gian, Sane, David C, Zhang, Huijuan, Hugger, Erin, Wheeler, Guy L, Borchardt, Ronald T, Wang, Binghe

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Preclinical Drug Metabolism and Pharmacokinetic Evaluation of GW844520, A Novel Anti-Malarial Mitochondrial Electron Transport Inhibitor von Xiang, Hong, McSurdy-Freed, Jeanelle, Moorthy, Ganesh S., Hugger, Erin, Bambal, Ramesh, Han, Chao, Ferrer, Santiago, Gargallo, Domingo, Davis, Charles B.

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Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295 von Qian, Xiangping, McDonald, Andrew, Zhou, Han-Jie, Adams, Nicholas D, Parrish, Cynthia A, Duffy, Kevin J, Fitch, Duke M, Tedesco, Rosanna, Ashcraft, Luke W, Yao, Bing, Jiang, Hong, Huang, Jennifer K, Marin, Melchor V, Aroyan, Carrie E, Wang, Jianchao, Ahmed, Seyed, Burgess, Joelle L, Chaudhari, Amita M, Donatelli, Carla A, Darcy, Michael G, Ridgers, Lance H, Newlander, Ken A, Schmidt, Stanley J, Chai, Deping, Colón, Mariela, Zimmerman, Michael N, Lad, Latesh, Sakowicz, Roman, Schauer, Stephen, Belmont, Lisa, Baliga, Ramesh, Pierce, Daniel W, Finer, Jeffrey T, Wang, Zhengping, Morgan, Bradley P, Morgans, David J, Auger, Kurt R, Sung, Chiu-Mei, Carson, Jeff D, Luo, Lusong, Hugger, Erin D, Copeland, Robert A, Sutton, David, Elliott, John D, Jackson, Jeffrey R, Wood, Kenneth W, Dhanak, Dashyant, Bergnes, Gustave, Knight, Steven D

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Comparative preclinical drug metabolism and pharmacokinetic evaluation of novel 4-aminoquinoline anti-malarials von Davis, Charles B., Bambal, Ramesh, Moorthy, Ganesh S., Hugger, Erin, Xiang, Hong, Park, Brian Kevin, Shone, Allison E., O’Neill, Paul M., Ward, Stephen A.

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Estimating intestinal mucosal permeation of compounds using Caco-2 cell monolayers von Gao, J, Hugger, E D, Beck-Westermeyer, M S, Borchardt, R T

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