Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers von Sivaramakrishnan, Manaswini, McCarthy, Kathleen D., Campagne, Sébastien, Huber, Sylwia, Meier, Sonja, Augustin, Angélique, Heckel, Tobias, Meistermann, Hélène, Hug, Melanie N., Birrer, Pascale, Moursy, Ahmed, Khawaja, Sarah, Schmucki, Roland, Berntenis, Nikos, Giroud, Nicolas, Golling, Sabrina, Tzouros, Manuel, Banfai, Balazs, Duran-Pacheco, Gonzalo, Lamerz, Jens, Hsiu Liu, Ying, Luebbers, Thomas, Ratni, Hasane, Ebeling, Martin, Cléry, Antoine, Paushkin, Sergey, Krainer, Adrian R., Allain, Frédéric H.-T., Metzger, Friedrich

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Synthetic single domain antibodies for the conformational trapping of membrane proteins von Zimmermann, Iwan, Egloff, Pascal, Hutter, Cedric Aj, Arnold, Fabian M, Stohler, Peter, Bocquet, Nicolas, Hug, Melanie N, Huber, Sylwia, Siegrist, Martin, Hetemann, Lisa, Gera, Jennifer, Gmür, Samira, Spies, Peter, Gygax, Daniel, Geertsma, Eric R, Dawson, Roger Jp, Seeger, Markus A

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SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands von Huber, Sylwia, Casagrande, Fabio, Hug, Melanie N, Wang, Lisha, Heine, Philipp, Kummer, Lutz, Plückthun, Andreas, Hennig, Michael

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Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulcerans von Dangy, Jean-Pierre, Scherr, Nicole, Gersbach, Philipp, Hug, Melanie N, Bieri, Raphael, Bomio, Claudio, Li, Jun, Huber, Sylwia, Altmann, Karl-Heinz, Pluschke, Gerd

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DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome von Richter, Hans, Satz, Alexander L, Bedoucha, Marc, Buettelmann, Bernd, Petersen, Ann C, Harmeier, Anja, Hermosilla, Ricardo, Hochstrasser, Remo, Burger, Dominique, Gsell, Bernard, Gasser, Rodolfo, Huber, Sylwia, Hug, Melanie N, Kocer, Buelent, Kuhn, Bernd, Ritter, Martin, Rudolph, Markus G, Weibel, Franziska, Molina-David, Judith, Kim, Jin-Ju, Santos, Javier Varona, Stihle, Martine, Georges, Guy J, Bonfil, R. Daniel, Fridman, Rafael, Uhles, Sabine, Moll, Solange, Faul, Christian, Fornoni, Alessia, Prunotto, Marco

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The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson’s disease brain as revealed by multicolor STED microscopy von Moors, Tim E., Maat, Christina A., Niedieker, Daniel, Mona, Daniel, Petersen, Dennis, Timmermans-Huisman, Evelien, Kole, Jeroen, El-Mashtoly, Samir F., Spycher, Liz, Zago, Wagner, Barbour, Robin, Mundigl, Olaf, Kaluza, Klaus, Huber, Sylwia, Hug, Melanie N., Kremer, Thomas, Ritter, Mirko, Dziadek, Sebastian, Geurts, Jeroen J. G., Gerwert, Klaus, Britschgi, Markus, van de Berg, Wilma D. J.

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Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance von Bocquet, Nicolas, Kohler, Josiane, Hug, Melanie N., Kusznir, Eric A., Rufer, Arne C., Dawson, Roger J., Hennig, Michael, Ruf, Armin, Huber, Walter, Huber, Sylwia

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Small molecule AX-024 reduces T cell proliferation independently of CD3ϵ/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain von Richter, Kirsten, Rufer, Arne C., Muller, Magali, Burger, Dominique, Casagrande, Fabio, Grossenbacher, Tabea, Huber, Sylwia, Hug, Melanie N., Koldewey, Philipp, D'Osualdo, Andrea, Schlatter, Daniel, Stoll, Theodor, Rudolph, Markus G.

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HLA antibody affinity determination: From HLA‐specific monoclonal antibodies to donor HLA specific antibodies (DSA) in patient serum von Hug, Melanie N., Keller, Sabrina, Marty, Talea, Gygax, Daniel, Meinel, Dominik, Spies, Peter, Handschin, Joëlle, Kleiser, Marc, Vazquez, Noemi, Linnik, Janina, Buchli, Rico, Claas, Frans, Heidt, Sebastiaan, Kramer, Cynthia S. M., Bezstarosti, Suzanne, Lee, Jar‐How, Schaub, Stefan, Hönger, Gideon

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Multi-parameter optimization: Development of a morpholin-3-one derivative with an improved kinetic profile for imaging monoacylglycerol lipase in the brain von He, Yingfang, Grether, Uwe, Taddio, Marco F., Meier, Carla, Keller, Claudia, Edelmann, Martin R., Honer, Michael, Huber, Sylwia, Wittwer, Matthias B., Heer, Dominik, Richter, Hans, Collin, Ludovic, Hug, Melanie N., Hilbert, Manuel, Postmus, Annemarieke G.J., Stevens, Anna Floor, van der Stelt, Mario, Krämer, Stefanie D., Schibli, Roger, Mu, Linjing, Gobbi, Luca C.

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Reply to Alarcon and Borroto: Small molecule AX-024 reduces T cell proliferation independently of CD3ε-Nck1 interaction at SH3.1 von Richter, Kirsten, Rufer, Arne C., Muller, Magali, Burger, Dominique, Casagrande, Fabio, Grossenbacher, Tabea, Huber, Sylwia, Hug, Melanie N., Koldewey, Philipp, D'Osualdo, Andrea, Schlatter, Daniel, Stoll, Theodor, Rudolph, Markus G.

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Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies von Moors, Tim E, Mona, Daniel, Luehe, Stefan, Duran-Pacheco, Gonzalo, Spycher, Liz, Mundigl, Olaf, Kaluza, Klaus, Huber, Sylwia, Hug, Melanie N, Kremer, Thomas, Ritter, Mirko, Dziadek, Sebastian, Dernick, Gregor, van de Berg, Wilma D J, Britschgi, Markus

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Diagnosis of whooping cough in Switzerland: differentiating Bordetella pertussis from Bordetella holmesii by polymerase chain reaction von Pittet, Laure F, Emonet, Stéphane, François, Patrice, Bonetti, Eve-Julie, Schrenzel, Jacques, Hug, Melanie, Altwegg, Martin, Siegrist, Claire-Anne, Posfay-Barbe, Klara M

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Rapid Detection of Methicillin-Resistant Staphylococcus aureus (MRSA) in Diverse Clinical Specimens by the BD GeneOhm MRSA Assay and Comparison with Culture von LUCKE, Katja, HOMBACH, Michael, HUG, Melanie, PFYFFER, Gaby E

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Novel β‐Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization von Benz, Joerg, Rufer, Arne C., Huber, Sylwia, Ehler, Andreas, Hug, Melanie, Topp, Andreas, Guba, Wolfgang, Hofmann, Eva Carolina, Jagasia, Ravi, Rodríguez Sarmiento, Rosa María

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Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors von Kuhn, Bernd, Ritter, Martin, Hornsperger, Benoit, Bell, Charles, Kocer, Buelent, Rombach, Didier, Lutz, Marius D. R., Gobbi, Luca, Kuratli, Martin, Bartelmus, Christian, Bürkler, Markus, Koller, Raffael, Tosatti, Paolo, Ruf, Iris, Guerard, Melanie, Pavlovic, Anto, Stephanus, Juliane, O’Hara, Fionn, Wetzl, Dennis, Saal, Wiebke, Stihle, Martine, Roth, Doris, Hug, Melanie, Huber, Sylwia, Heer, Dominik, Kroll, Carsten, Topp, Andreas, Schneider, Manfred, Gertsch, Jürg, Glasmacher, Sandra, van der Stelt, Mario, Martella, Andrea, Wittwer, Matthias Beat, Collin, Ludovic, Benz, Jörg, Richter, Hans, Grether, Uwe

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Small molecule AX-024 reduces T cell proliferation independently of CD3?/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain von Richter, Kirsten, Rufer, Arne C., Muller, Magali, Burger, Dominique, Casagrande, Fabio, Grossenbacher, Tabea, Huber, Sylwia, Hug, Melanie N., Koldewey, Philipp, D'Osualdo, Andrea, Schlatter, Daniel, Stoll, Theodor, Rudolph, Markus G.

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SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands von Huber, Sylwia, Casagrande, Fabio, Hug, Melanie N, Wang, Lisha, Heine, Philipp, Kummer, Lutz, Plückthun, Andreas, Hennig, Michael

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Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods von Huber, Walter, Sinopoli, Alessandro, Kohler, Josiane, Hug, Melanie, Ruf, Armin, Huber, Sylwia

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Elucidation of direct competition and allosteric modulation of small-molecular-weight protein ligands using surface plasmon resonance methods: COMPETITION AND ALLOSTERIC MODULATION von Huber, Walter, Sinopoli, Alessandro, Kohler, Josiane, Hug, Melanie, Ruf, Armin, Huber, Sylwia

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