Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner von Singh, Samer, Tokhunts, Robert, Baubet, Valerie, Goetz, John A, Huang, Zhen Jane, Schilling, Neal S, Black, Kendall E, MacKenzie, Todd A, Dahmane, Nadia, Robbins, David J

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Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity von Meng, Bo, Abdullahi, Adam, Ferreira, Isabella A. T. M., Goonawardane, Niluka, Saito, Akatsuki, Kimura, Izumi, Yamasoba, Daichi, Gerber, Pehuén Pereyra, Fatihi, Saman, Rathore, Surabhi, Zepeda, Samantha K., Papa, Guido, Kemp, Steven A., Ikeda, Terumasa, Toyoda, Mako, Tan, Toong Seng, Kuramochi, Jin, Mitsunaga, Shigeki, Ueno, Takamasa, Shirakawa, Kotaro, Takaori-Kondo, Akifumi, Brevini, Teresa, Mallery, Donna L., Charles, Oscar J., Bowen, John E., Joshi, Anshu, Walls, Alexandra C., Jackson, Laurelle, Martin, Darren, Smith, Kenneth G. C., Bradley, John, Briggs, John A. G., Choi, Jinwook, Madissoon, Elo, Meyer, Kerstin B., Mlcochova, Petra, Ceron-Gutierrez, Lourdes, Doffinger, Rainer, Teichmann, Sarah A., Fisher, Andrew J., Pizzuto, Matteo S., de Marco, Anna, Corti, Davide, Hosmillo, Myra, Lee, Joo Hyeon, James, Leo C., Thukral, Lipi, Veesler, David, Sigal, Alex, Sampaziotis, Fotios, Goodfellow, Ian G., Matheson, Nicholas J., Sato, Kei, Gupta, Ravindra K.

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Single-cell multi-omics analysis of the immune response in COVID-19 von Stephenson, Emily, Reynolds, Gary, Botting, Rachel A., Calero-Nieto, Fernando J., Morgan, Michael D., Tuong, Zewen Kelvin, Bach, Karsten, Sungnak, Waradon, Worlock, Kaylee B., Yoshida, Masahiro, Kumasaka, Natsuhiko, Kania, Katarzyna, Engelbert, Justin, Olabi, Bayanne, Spegarova, Jarmila Stremenova, Wilson, Nicola K., Mende, Nicole, Jardine, Laura, Gardner, Louis C. S., Goh, Issac, Horsfall, Dave, McGrath, Jim, Webb, Simone, Mather, Michael W., Lindeboom, Rik G. H., Dann, Emma, Huang, Ni, Polanski, Krzysztof, Prigmore, Elena, Gothe, Florian, Scott, Jonathan, Payne, Rebecca P., Baker, Kenneth F., Hanrath, Aidan T., Schim van der Loeff, Ina C. D., Barr, Andrew S., Sanchez-Gonzalez, Amada, Bergamaschi, Laura, Mescia, Federica, Barnes, Josephine L., Kilich, Eliz, de Wilton, Angus, Saigal, Anita, Saleh, Aarash, Janes, Sam M., Smith, Claire M., Gopee, Nusayhah, Wilson, Caroline, Coupland, Paul, Coxhead, Jonathan M., Kiselev, Vladimir Yu, van Dongen, Stijn, Bacardit, Jaume, King, Hamish W., Rostron, Anthony J., Simpson, A. John, Hambleton, Sophie, Laurenti, Elisa, Lyons, Paul A., Meyer, Kerstin B., Nikolić, Marko Z., Duncan, Christopher J. A., Smith, Kenneth G. C., Teichmann, Sarah A., Clatworthy, Menna R., Marioni, John C., Göttgens, Berthold, Haniffa, Muzlifah

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Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy von Kondo, Asami, Shahpasand, Koorosh, Mannix, Rebekah, Qiu, Jianhua, Moncaster, Juliet, Chen, Chun-Hau, Yao, Yandan, Lin, Yu-Min, Driver, Jane A., Sun, Yan, Wei, Shuo, Luo, Man-Li, Albayram, Onder, Huang, Pengyu, Rotenberg, Alexander, Ryo, Akihide, Goldstein, Lee E., Pascual-Leone, Alvaro, McKee, Ann C., Meehan, William, Zhou, Xiao Zhen, Lu, Kun Ping

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The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated α-MSH in keratinocytes via Nrf2-media... von Hseu, You-Cheng, Vudhya Gowrisankar, Yugandhar, Wang, Li-Wei, Zhang, Yan-Zhen, Chen, Xuan-Zao, Huang, Pei-Jane, Yen, Hung-Rong, Yang, Hsin-Ling

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Lauric Acid Is an Inhibitor of Clostridium difficile Growth in Vitro and Reduces Inflammation in a Mouse Infection Model von Yang, Hsiao-Ting, Chen, Jenn-Wei, Rathod, Jagat, Jiang, Yu-Zhen, Tsai, Pei-Jane, Hung, Yuan-Pin, Ko, Wen-Chien, Paredes-Sabja, Daniel, Huang, I-Hsiu

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A thermostable, closed SARS-CoV-2 spike protein trimer von Xiong, Xiaoli, Qu, Kun, Ciazynska, Katarzyna A., Hosmillo, Myra, Carter, Andrew P., Ebrahimi, Soraya, Ke, Zunlong, Scheres, Sjors H. W., Bergamaschi, Laura, Grice, Guinevere L., Zhang, Ying, Nathan, James A., Baker, Stephen, James, Leo C., Baxendale, Helen E., Goodfellow, Ian, Doffinger, Rainer, Briggs, John A. G.

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SARS-CoV-2 evolution during treatment of chronic infection von Kemp, Steven A., Collier, Dami A., Datir, Rawlings P., Ferreira, Isabella A. T. M., Gayed, Salma, Jahun, Aminu, Hosmillo, Myra, Rees-Spear, Chloe, Mlcochova, Petra, Lumb, Ines Ushiro, Roberts, David J., Chandra, Anita, Temperton, Nigel, Sharrocks, Katherine, Blane, Elizabeth, Modis, Yorgo, Leigh, Kendra E., Briggs, John A. G., van Gils, Marit J., Smith, Kenneth G. C., Bradley, John R., Smith, Chris, Doffinger, Rainer, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Pollock, David D., Goldstein, Richard A., Smielewska, Anna, Skittrall, Jordan P., Gouliouris, Theodore, Goodfellow, Ian G., Gkrania-Klotsas, Effrossyni, Illingworth, Christopher J. R., McCoy, Laura E., Gupta, Ravindra K.

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Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 von Collier, Dami A., Ferreira, Isabella A. T. M., Kotagiri, Prasanti, Datir, Rawlings P., Lim, Eleanor Y., Touizer, Emma, Meng, Bo, Abdullahi, Adam, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, Le Gresley, Emma, Caputo, Daniela, Bergamaschi, Laura, Smith, Kenneth G. C., Bradley, John R., Ceron-Gutierrez, Lourdes, Cortes-Acevedo, Paulina, Barcenas-Morales, Gabriela, Linterman, Michelle A., McCoy, Laura E., Davis, Chris, Thomson, Emma, Lyons, Paul A., McKinney, Eoin, Doffinger, Rainer, Wills, Mark, Gupta, Ravindra K.

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Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies von Collier, Dami A., De Marco, Anna, Ferreira, Isabella A. T. M., Meng, Bo, Datir, Rawlings P., Walls, Alexandra C., Kemp, Steven A., Bassi, Jessica, Pinto, Dora, Silacci-Fregni, Chiara, Bianchi, Siro, Tortorici, M. Alejandra, Bowen, John, Culap, Katja, Jaconi, Stefano, Cameroni, Elisabetta, Snell, Gyorgy, Pizzuto, Matteo S., Pellanda, Alessandra Franzetti, Garzoni, Christian, Riva, Agostino, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, McCoy, Laura E., Smith, Kenneth G. C., Bradley, John R., Temperton, Nigel, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Harvey, William, Virgin, Herbert W., Lanzavecchia, Antonio, Piccoli, Luca, Doffinger, Rainer, Wills, Mark, Veesler, David, Corti, Davide, Gupta, Ravindra K.

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Metformin-Induced Reduction of CD39 and CD73 Blocks Myeloid-Derived Suppressor Cell Activity in Patients with Ovarian Cancer von Li, Lifeng, Wang, Liping, Li, Jieyao, Fan, Zhirui, Yang, Li, Zhang, Zhen, Zhang, Chaoqi, Yue, Dongli, Qin, Guohui, Zhang, Tengfei, Li, Feng, Chen, Xinfeng, Ping, Yu, Wang, Dan, Gao, Qun, He, Qianyi, Huang, Lan, Li, Hong, Huang, Jianmin, Zhao, Xuan, Xue, Wenhua, Sun, Zhi, Lu, Jingli, Yu, Jane J, Zhao, Jie, Zhang, Bin, Zhang, Yi

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Cancer-cell-secreted CXCL11 promoted CD8 + T cells infiltration through docetaxel-induced-release of HMGB1 in NSCLC von Gao, Qun, Wang, Shumin, Chen, Xinfeng, Cheng, Shaoyan, Zhang, Zhen, Li, Feng, Huang, Lan, Yang, Yang, Zhou, Bin, Yue, Dongli, Wang, Dan, Cao, Ling, Maimela, Nomathamsanqa Resegofetse, Zhang, Bin, Yu, Jane, Wang, Liping, Zhang, Yi

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Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission von Rivett, Lucy, Sridhar, Sushmita, Sparkes, Dominic, Routledge, Matthew, Jones, Nick K, Forrest, Sally, Young, Jamie, Pereira-Dias, Joana, Hamilton, William L, Ferris, Mark, Torok, M Estee, Meredith, Luke, Curran, Martin D, Fuller, Stewart, Chaudhry, Afzal, Shaw, Ashley, Samworth, Richard J, Bradley, John R, Dougan, Gordon, Smith, Kenneth Gc, Lehner, Paul J, Matheson, Nicholas J, Wright, Giles, Goodfellow, Ian G, Baker, Stephen, Weekes, Michael P

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SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity von Meng, Bo, Choi, Jinwook, Baker, Stephen, Dougan, Gordon, Hess, Christoph, Kingston, Nathalie, Lehner, Paul J., Lyons, Paul A., Matheson, Nicholas J., Owehand, Willem H., Saunders, Caroline, Summers, Charlotte, Thaventhiran, James E.D., Toshner, Mark, Weekes, Michael P., Maxwell, Patrick, Shaw, Ashley, Calder, Jo, Canna, Laura, Domingo, Jason, Fuller, Stewart, Harris, Julie, Hewitt, Sarah, Kennet, Jane, Jose, Sherly, Kourampa, Jenny, Meadows, Anne, O’Brien, Criona, Price, Jane, Publico, Cherry, Rastall, Rebecca, Ribeiro, Carla, Rowlands, Jane, Ruffolo, Valentina, Tordesillas, Hugo, Dunmore, Benjamin J., Gräf, Stefan, Hodgson, Josh, Huang, Christopher, Hunter, Kelvin, Jones, Emma, Legchenko, Ekaterina, Matara, Cecilia, Martin, Jennifer, O’Donnell, Ciara, Pointon, Linda, Shih, Joy, Sutcliffe, Rachel, Tilly, Tobias, Treacy, Carmen, Tong, Zhen, Wylot, Marta, Betancourt, Ariana, Bower, Georgie, Cossetti, Chiara, De Sa, Aloka, Epping, Madeline, Gleadall, Nick, Hinch, Andrew, Jackson, Sarah, Jarvis, Isobel, Krishna, Ben, Omarjee, Ommar, Perera, Marianne, Potts, Martin, Richoz, Nathan, Romashova, Veronika, Stefanucci, Luca, Strezlecki, Mateusz, Turner, Lori, De Bie, Eckart M.D.D., Bunclark, Katherine, Josipovic, Masa, Mackay, Michael, Allison, John, Butcher, Helen, Caputo, Daniela, Dewhurst, Eleanor, Furlong, Anita, Graves, Barbara, Gray, Jennifer, Ivers, Tasmin, Le Gresley, Emma, Linger, Rachel, Meloy, Sarah, Muldoon, Francesca, Ovington, Nigel, Papadia, Sofia, Stark, Hannah, Stirrups, Kathleen E., Townsend, Paul, Walker, Neil, Webster, Jennifer, Scholtes, Ingrid, Hein, Sabine, King, Rebecca, Bradley, John R., Smith, Kenneth G.C., Lee, Joo Hyeon, Gupta, Ravindra K.

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Adipose tissue stiffness in the development of metabolic diseases von Tsai, Yau‐Sheng, Huang, Ann, Lin, Yi‐Shiuan, Kao, Ling‐Zhen, Tang, Ming‐Jer, Tsai, Pei‐Jane

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Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase von Butler, Christopher R., Beck, Elizabeth M., Harris, Anthony, Huang, Zhen, McAllister, Laura A., am Ende, Christopher W., Fennell, Kimberly, Foley, Timothy L., Fonseca, Kari, Hawrylik, Steven J., Johnson, Douglas S., Knafels, John D., Mente, Scot, Noell, G. Stephen, Pandit, Jayvardhan, Phillips, Tracy B., Piro, Justin R., Rogers, Bruce N., Samad, Tarek A., Wang, Jane, Wan, Shuangyi, Brodney, Michael A.

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Inflammation‐induced macrophage lysyl oxidase in adipose stiffening and dysfunction in obesity von Huang, An, Lin, Yi‐Shiuan, Kao, Ling‐Zhen, Chiou, Yu‐Wei, Lee, Gang‐Hui, Lin, Hsi‐Hui, Wu, Chih‐Hsing, Chang, Chin‐Sung, Lee, Kuo‐Ting, Hsueh, Yuan‐Yu, Tsai, Pei‐Jane, Tang, Ming‐Jer, Tsai, Yau‐Sheng

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Effect of lithofacies on pore structure of the Cambrian organic‐rich shale in northern Guizhou, China von Xia, Peng, Li, Hongnan, Fu, Yong, Qiao, Wenlang, Guo, Chuan, Yang, Zhen, Huang, Jinqiang, Mou, Yuliang

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Navigating Turbulent Waves of Emotions: Multi-Level Stress and Coping Among Chinese Men Who Have Sex with Men Living with HIV von Wang, Liying, Simoni, Jane M, Hua, Wenzhe, Chen, Lingxiao, Zheng, Huang, Ning, Zhen, Yuwen, Weichao

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A role for the transcription factor STAT5 in antagonizing CD8+ T cell exhaustion von Beltra, Jean-Christophe, Manne, Sasikanth, Abdel-Hakeem, Mohamed S, Nzingha, Kito, Zhang, Zhen, Huang, Hua, Kurachi, Makoto, Muroyama, Yuki, Huang, Yinghui Jane, Su, Leon L, Picton, Lora, Decaluwe, Helene, Huang, Alexander C, Berger, Shelley L, Garcia, Christopher K, Wherry, E. John

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