Structural Basis for Apelin Control of the Human Apelin Receptor von Ma, Yingli, Yue, Yang, Ma, Yanbin, Zhang, Qing, Zhou, Qingtong, Song, Yunpeng, Shen, Yuqing, Li, Xun, Ma, Xiaochuan, Li, Chao, Hanson, Michael A., Han, Gye Won, Sickmier, E. Allen, Swaminath, Gayathri, Zhao, Suwen, Stevens, Raymond C., Hu, Liaoyuan A., Zhong, Wenge, Zhang, Mingqiang, Xu, Fei

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APLNR Regulates IFN-γ signaling via β-arrestin 1 mediated JAK-STAT1 pathway in melanoma cells von Liu, Yingying, Ma, Xiaochuan, Yang, Hui, Li, Xun, Ma, Yingli, Ason, Brandon, Liu, Suling, Hu, Liaoyuan A

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Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism von Wang, Jia, Song, Xianqiang, Zhang, Dandan, Chen, Xiaoqing, Li, Xun, Sun, Yaping, Li, Cui, Song, Yunpeng, Ding, Yao, Ren, Ruobing, Harrington, Essa Hu, Hu, Liaoyuan A., Zhong, Wenge, Xu, Cen, Huang, Xin, Wang, Hong-Wei, Ma, Yingli

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Loss of APJ mediated β-arrestin signalling improves high-fat diet induced metabolic dysfunction but does not alter cardiac function in mice von Li, Na, Ma, Xiaochuan, Ban, Ting, Xu, Shaohua, Ma, Yingli, Ason, Brandon, Hu, Liaoyuan A

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Fragment-Based Computational Method for Designing GPCR Ligands von Li, Yan, Sun, Yaping, Song, Yunpeng, Dai, Dongcheng, Zhao, Zhixiong, Zhang, Qing, Zhong, Wenge, Hu, Liaoyuan A, Ma, Yingli, Li, Xun, Wang, Renxiao

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Structure-guided discovery of a single-domain antibody agonist against human apelin receptor von Ma, Yanbin, Ding, Yao, Song, Xianqiang, Ma, Xiaochuan, Li, Xun, Zhang, Ning, Song, Yunpeng, Sun, Yaping, Shen, Yuqing, Zhong, Wenge, Hu, Liaoyuan A, Ma, Yingli, Zhang, Mei-Yun

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Different conformational responses of the β2-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline von Yang, Fan, Ling, Shenglong, Zhou, Yingxin, Zhang, Yanan, Lv, Pei, Liu, Sanling, Fang, Wei, Sun, Wenjing, Hu, Liaoyuan A, Zhang, Longhua, Shi, Pan, Tian, Changlin

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GPCR structure and function relationship: identification of a biased apelin receptor mutant von Ban, Ting, Li, Xun, Ma, Xiaochuan, Yang, Hui, Song, Yunpeng, Sun, Yaping, Shen, Michelle, Li, Na, Zhang, Mei-Yun, Ma, Yingli, Zhong, Wenge, Zhang, Mingqiang, Hu, Liaoyuan A

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A general Fc engineering platform for the next generation of antibody therapeutics von Chen, Da, Zhao, Yingjie, Li, Mingyu, Shang, Hang, Li, Na, Li, Fan, Wang, Wei, Wang, Yuan, Jin, Ruina, Liu, Shiyu, Li, Xun, Gao, Shan, Tian, Yujie, Li, Ruonan, Li, Huanhuan, Zhang, Yongyan, Du, Mingjuan, Cao, Youjia, Zhang, Yan, Li, Xin, Huang, Yi, Hu, Liaoyuan A, Li, Fubin, Zhang, Hongkai

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Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α2C Adrenergic Receptor von Chen, Xiaoyu, Xu, Yueming, Qu, Lu, Wu, Lijie, Han, Gye Won, Guo, Yu, Wu, Yiran, Zhou, Qingtong, Sun, Qianqian, Chu, Cenfeng, Yang, Jie, Yang, Liu, Wang, Quan, Yuan, Shuguang, Wang, Ling, Hu, Tao, Tao, Houchao, Sun, Yaping, Song, Yunpeng, Hu, Liaoyuan, Liu, Zhi-Jie, Stevens, Raymond C., Zhao, Suwen, Wu, Dong, Zhong, Guisheng

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Author Correction: Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism von Wang, Jia, Song, Xianqiang, Zhang, Dandan, Chen, Xiaoqing, Li, Xun, Sun, Yaping, Li, Cui, Song, Yunpeng, Ding, Yao, Ren, Ruobing, Harrington, Essa Hu, Hu, Liaoyuan A., Zhong, Wenge, Xu, Cen, Huang, Xin, Wang, Hong-Wei, Ma, Yingli

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Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands von Hu, Liaoyuan A, Zhou, Tian, Ahn, Jinwoo, Wang, Shuli, Zhou, Julia, Hu, Yi, Liu, Qingyun

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Function-based high-throughput screening for antibody antagonists and agonists against G protein-coupled receptors von Ren, Huanhuan, Li, Jian, Zhang, Ning, Hu, Liaoyuan A., Ma, Yingli, Tagari, Philip, Xu, Jianqing, Zhang, Mei-Yun

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Cardiovascular response to small-molecule APJ activation von Ason, Brandon, Chen, Yinhong, Guo, Qi, Hoagland, Kimberly M, Chui, Ray W, Fielden, Mark, Sutherland, Weston, Chen, Rhonda, Zhang, Ying, Mihardja, Shirley, Ma, Xiaochuan, Li, Xun, Sun, Yaping, Liu, Dongming, Nguyen, Khanh, Wang, Jinghong, Li, Ning, Rajamani, Sridharan, Qu, Yusheng, Gao, BaoXi, Boden, Andrea, Chintalgattu, Vishnu, Turk, Jim R, Chan, Joyce, Hu, Liaoyuan A, Dransfield, Paul, Houze, Jonathan, Wong, Jingman, Ma, Ji, Pattaropong, Vatee, Véniant, Murielle M, Vargas, Hugo M, Swaminath, Gayathri, Khakoo, Aarif Y

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Identification of Surrogate Agonists and Antagonists for Orphan G-Protein-Coupled Receptor GPR139 von Hu, Liaoyuan A., Tang, Pauline M., Eslahi, Nima K., Zhou, Tian, Barbosa, Joseph, Liu, Qingyun

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Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4 von Chen, Wei, Berge, Derk ten, Brown, Jeff, Ahn, Seungkirl, Hu, Liaoyuan A., Miller, William E., Caron, Marc G., Barak, Larry S., Nusse, Roel, Lefkowitz, Robert J.

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Beta-arrestin 1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins von Chen, Wei, Hu, Liaoyuan A, Semenov, Mikhail V, Yanagawa, Shinichi

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A homogeneous G protein-coupled receptor ligand binding assay based on time-resolved fluorescence resonance energy transfer von Hu, Liaoyuan A, Zhou, Tian, Hamman, Brian D, Liu, Qingyun

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Structural insights into ligand recognition and selectivity of somatostatin receptors von Zhao, Wenli, Han, Shuo, Qiu, Na, Feng, Wenbo, Lu, Mengjie, Zhang, Wenru, Wang, Mu, Zhou, Qingtong, Chen, Shutian, Xu, Wei, Du, Juan, Chu, Xiaojing, Yi, Cuiying, Dai, Antao, Hu, Liaoyuan, Shen, Michelle Y., Sun, Yaping, Zhang, Qing, Ma, Yingli, Zhong, Wenge, Yang, Dehua, Wang, Ming-Wei, Wu, Beili, Zhao, Qiang

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Regulation of Membrane Targeting of the G Protein-coupled Receptor Kinase 2 by Protein Kinase A and Its Anchoring Protein AKAP79 von Cong, Mei, Perry, Stephen J., Lin, Fang-Tsyr, Fraser, Iain D., Hu, Liaoyuan A., Chen, Wei, Pitcher, Julie A., Scott, John D., Lefkowitz, Robert J.

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