Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation von Tang, Weixin, Hu, Johnny H., Liu, David R.

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Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents von Gao, Xue, Tao, Yong, Lamas, Veronica, Huang, Mingqian, Yeh, Wei-Hsi, Pan, Bifeng, Hu, Yu-Juan, Hu, Johnny H., Thompson, David B., Shu, Yilai, Li, Yamin, Wang, Hongyang, Yang, Shiming, Xu, Qiaobing, Polley, Daniel B., Liberman, M. Charles, Kong, Wei-Jia, Holt, Jeffrey R., Chen, Zheng-Yi, Liu, David R.

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Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo von Zuris, John A, Thompson, David B, Shu, Yilai, Guilinger, John P, Bessen, Jeffrey L, Hu, Johnny H, Maeder, Morgan L, Joung, J Keith, Chen, Zheng-Yi, Liu, David R

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Evolved Cas9 variants with broad PAM compatibility and high DNA specificity von Hu, Johnny H., Miller, Shannon M., Geurts, Maarten H., Tang, Weixin, Chen, Liwei, Sun, Ning, Zeina, Christina M., Gao, Xue, Rees, Holly A., Lin, Zhi, Liu, David R.

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Treatment of monogenic and digenic dominant genetic hearing loss by CRISPR-Cas9 ribonucleoprotein delivery in vivo von Tao, Yong, Lamas, Veronica, Du, Wan, Zhu, Wenliang, Li, Yiran, Whittaker, Madelynn N., Zuris, John A., Thompson, David B., Rameshbabu, Arun Prabhu, Shu, Yilai, Gao, Xue, Hu, Johnny H., Pei, Charles, Kong, Wei-Jia, Liu, Xuezhong, Wu, Hao, Kleinstiver, Benjamin P., Liu, David R., Chen, Zheng-Yi

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Chemical Biology Approaches to Genome Editing: Understanding, Controlling, and Delivering Programmable Nucleases von Hu, Johnny H., Davis, Kevin M., Liu, David R.

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A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells von Chaikind, Brian, Bessen, Jeffrey L, Thompson, David B, Hu, Johnny H, Liu, David R

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Structure and mechanism of the UvrA–UvrB DNA damage sensor von Pakotiprapha, Danaya, Samuels, Martin, Shen, Koning, Hu, Johnny H, Jeruzalmi, David

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N‐Substituted Acridinium as a Multi‐Responsive Recognition Unit in Supramolecular Chemistry von Jacquot de Rouville, Henri‐Pierre, Hu, Johnny, Heitz, Valérie

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CRISPR/Cas9‐Mediated Fluorescent Tagging of Endogenous Proteins in Human Pluripotent Stem Cells von Sharma, Arun, Toepfer, Christopher N., Ward, Tarsha, Wasson, Lauren, Agarwal, Radhika, Conner, David A., Hu, Johnny H., Seidman, Christine E.

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Cover Feature: Self‐Assembled Bis‐Acridinium Tweezer Equilibria Controlled by Multi‐Responsive Properties (Chem. Eur. J. 44/2024) von Hu, Johnny, Launay, Jean‐Pierre, Chaumont, Alain, Heitz, Valérie, Jacquot de Rouville, Henri‐Pierre

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Self‐Assembled Bis‐Acridinium Tweezer Equilibria Controlled by Multi‐Responsive Properties von Hu, Johnny, Launay, Jean‐Pierre, Chaumont, Alain, Heitz, Valérie, Jacquot de Rouville, Henri‐Pierre

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Front Cover: Dual‐Readout of the Mechanical Response of a Bis‐acridinium [2]Rotaxane (Chem. Eur. J. 71/2022) von Hu, Johnny, Adrouche, Sonia, Gauthier, Etienne S., Le Breton, Nolwenn, Cecchini, Marco, Gourlaouen, Christophe, Choua, Sylvie, Heitz, Valérie, Jacquot de Rouville, Henri‐Pierre

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Dual-Readout of the Mechanical Response of a Bis-acridinium 2Rotaxane von Hu, Johnny, Adrouche, Sonia, Gauthier, Etienne S, Le Breton, Nolwenn, Cecchini, Marco, Gourlaouen, Christophe, Choua, Sylvie, Heitz, Valérie, Jacquot de Rouville, Henri-Pierre

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Dual‐Readout of the Mechanical Response of a Bis‐acridinium [2]Rotaxane von Hu, Johnny, Adrouche, Sonia, Gauthier, Etienne S., Le Breton, Nolwenn, Cecchini, Marco, Gourlaouen, Christophe, Choua, Sylvie, Heitz, Valérie, Jacquot de Rouville, Henri‐Pierre

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A Bis‐Acridinium Macrocycle as Multi‐Responsive Receptor and Selective Phase‐Transfer Agent of Perylene von Hu, Johnny, Ward, Jas S., Chaumont, Alain, Rissanen, Kari, Vincent, Jean‐Marc, Heitz, Valérie, Jacquot de Rouville, Henri‐Pierre

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Solid‐State Assembly by Chelating Chalcogen Bonding in Quinodimethane Tetraesters Fused with a Chalcogenadiazole von Ishigaki, Yusuke, Asai, Kota, Jacquot de Rouville, Henri‐Pierre, Shimajiri, Takuya, Hu, Johnny, Heitz, Valérie, Suzuki, Takanori

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A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells von Chaikind, Brian, Bessen, Jeffrey L, Thompson, David B, Hu, Johnny H, Liu, David R

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Amyloidosis presenting as lower gastrointestinal hemorrhage von Spier, Bret J, Einstein, Michael, Johnson, Eric A, Zuricik, 3rd, Andrew O, Hu, Johnny L, Pfau, Patrick R

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Directed evolution of Cas9 for mammalian genome editing von Hu, Johnny H

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