Discovery of Pyrophosphate Diesters as Tunable, Soluble, and Bioorthogonal Linkers for Site-Specific Antibody–Drug Conjugates von Kern, Jeffrey C, Cancilla, Mark, Dooney, Deborah, Kwasnjuk, Kristen, Zhang, Rena, Beaumont, Maribel, Figueroa, Isabel, Hsieh, SuChun, Liang, Linda, Tomazela, Daniela, Zhang, Jeffrey, Brandish, Philip E, Palmieri, Anthony, Stivers, Peter, Cheng, Mangeng, Feng, Guo, Geda, Prasanthi, Shah, Sanjiv, Beck, Andrew, Bresson, Damien, Firdos, Juhi, Gately, Dennis, Knudsen, Nick, Manibusan, Anthony, Schultz, Peter G, Sun, Ying, Garbaccio, Robert M

Volltext

Effects of PEGylation and immune complex formation on the pharmacokinetics and biodistribution of recombinant interleukin 10 in mice von Alvarez, Hamsell M, So, On-Yee, Hsieh, SuChun, Shinsky-Bjorde, Natasha, Ma, Huiping, Song, Yaoli, Pang, Yinuo, Marian, Melinda, Escandón, Enrique

Volltext

Development of a novel capillary electrophoresis-based approach for detection of anti-drug antibody responses von Zhang, Shuli, Chen, Minchao, Zhou, Siqun, Raoufi, Fahimeh, Wiswell, Derek, Hsieh, SuChun, Seghezzi, Wolfgang

Volltext

Top-down LC-MS quantitation of intact denatured and native monoclonal antibodies in biological samples von Zhang, Liyun, Vasicek, Lisa A, Hsieh, SuChun, Zhang, Shuli, Bateman, Kevin P, Henion, Jack

Volltext

Quantitation of a Therapeutic Antibody in Serum Using Intact Sequential Affinity Capture, Trypsin Digestion, and LC-MS/MS von Vasicek, Lisa A, Spellman, Daniel S, Hsieh, SuChun, Seghezzi, Wolfgang, Zhang, Shuli, Santostefano, Michael, Bateman, Kevin P

Volltext

Characterization of murine CEACAM1 in vivo reveals low expression on CD8 + T cells and no tumor growth modulating activity by anti-CEACAM1 mAb CC1 von McLeod, Robbie L, Angagaw, Minilik H, Baral, Toya Nath, Liu, Liming, Moniz, Raymond Joseph, Laskey, Jason, Hsieh, SuChun, Lee, Mike, Han, Jin-Hwan, Issafras, Hassan, Javaid, Sarah, Loboda, Andrey, Sadekova, Svetlana, O'Connor, Joann A, Tse, Archie, Punnonen, Juha

Volltext

The Role of FcRn in the Disposition, Metabolism and Pharmacokinetics of Soluble Non‐Crosslinking Immune Complexes von Alvarez, Hamsell M., So, On‐Yee, Hsieh, SuChun, Shinsky‐Bjorde, Natalie, Ma, Huiping, Song, Yaoli, Pang, Yinuo, Marian, Melinda, Escandón, Enrique

Volltext

Antibody-drug conjugates: integrated bioanalytical and biodisposition assessments in lead optimization and selection von Beaumont, Maribel, Tomazela, Daniela, Hodges, Douglas, Ermakov, Grigori, Hsieh, Edward, Figueroa, Isabel, So, On-Yee, Song, Yaoli, Ma, Huiping, Antonenko, Svetlana, Mengesha, Wondwessen, Zhang, Yi Wei, Zhang, Shuli, Hseih, SuChun, Ayanoglu, Gulesi, Du, Xiaoyan, Rimmer, Eric, Judo, Michael, Vives, Franklin, Yearley, Jennifer H., Moon, Christina, Manibusan, Anthony, Knudsen, Nick, Beck, Andy, Bresson, Damien, Gately, Dennis, Neupane, Divas, Escandón, Enrique

Volltext