Ribosome-Mediated Specificity in Hox mRNA Translation and Vertebrate Tissue Patterning von Kondrashov, Nadya, Pusic, Aya, Stumpf, Craig R., Shimizu, Kunihiko, Hsieh, Andrew C., Xue, Shifeng, Ishijima, Junko, Shiroishi, Toshihiko, Barna, Maria

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PI3K-AKT-mTOR signaling in prostate cancer progression and androgen deprivation therapy resistance von Edlind, Merritt P, Hsieh, Andrew C

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Targeting Eukaryotic Translation Initiation Factor 4E (eIF4E) in Cancer von HSIEH, Andrew C, RUGGERO, Davide

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The Untranslated Regions of mRNAs in Cancer von Schuster, Samantha L, Hsieh, Andrew C

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Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E von Hsieh, Andrew C., Costa, Maria, Zollo, Ornella, Davis, Cole, Feldman, Morris E., Testa, Joseph R., Meyuhas, Oded, Shokat, Kevan M., Ruggero, Davide

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Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer von Lim, Yiting, Arora, Sonali, Schuster, Samantha L., Corey, Lukas, Fitzgibbon, Matthew, Wladyka, Cynthia L., Wu, Xiaoying, Coleman, Ilsa M., Delrow, Jeffrey J., Corey, Eva, True, Lawrence D., Nelson, Peter S., Ha, Gavin, Hsieh, Andrew C.

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The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs von Hamm, Danielle C, Paatela, Ellen M, Bennett, Sean R, Wong, Chao-Jen, Campbell, Amy E, Wladyka, Cynthia L, Smith, Andrew A, Jagannathan, Sujatha, Hsieh, Andrew C, Tapscott, Stephen J

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Defining the therapeutic selective dependencies for distinct subtypes of PI3K pathway-altered prostate cancers von Mao, Ninghui, Zhang, Zeda, Lee, Young Sun, Choi, Danielle, Rivera, Aura Agudelo, Li, Dan, Lee, Cindy, Haywood, Samuel, Chen, Xiaoping, Chang, Qing, Xu, Guotai, Chen, Hsuan-An, de Stanchina, Elisa, Sawyers, Charles, Rosen, Neal, Hsieh, Andrew C., Chen, Yu, Carver, Brett S.

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Increased translation driven by non-canonical EZH2 creates a synthetic vulnerability in enzalutamide-resistant prostate cancer von Chatterjee, Shankha S., Linares, Juan F., Cid-Diaz, Tania, Duran, Angeles, Khan, Mohd. Imran K., Osrodek, Marta, Brady, Nicholas J., Reina-Campos, Miguel, Marzio, Antonio, Venkadakrishnan, Varadha Balaji, Bakht, Martin K., Khani, Francesca, Mosquera, Juan Miguel, Robinson, Brian D., Moyer, Jenna, Elemento, Olivier, Hsieh, Andrew C., Goodrich, David W., Rickman, David S., Beltran, Himisha, Moscat, Jorge, Diaz-Meco, Maria T.

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Assessing gene-level translational control from ribosome profiling von Olshen, Adam B, Hsieh, Andrew C, Stumpf, Craig R, Olshen, Richard A, Ruggero, Davide, Taylor, Barry S

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A bladder cancer patient-derived xenograft displays aggressive growth dynamics in vivo and in organoid culture von Cai, Elise Y., Garcia, Jose, Liu, Yuzhen, Vakar-Lopez, Funda, Arora, Sonali, Nguyen, Holly M., Lakely, Bryce, Brown, Lisha, Wong, Alicia, Montgomery, Bruce, Lee, John K., Corey, Eva, Wright, Jonathan L., Hsieh, Andrew C., Lam, Hung-Ming

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Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer von Che, Meixia, Chaturvedi, Aashi, Munro, Sarah A., Pitzen, Samuel P., Ling, Alex, Zhang, Weijie, Mentzer, Josh, Ku, Sheng-Yu, Puca, Loredana, Zhu, Yanyun, Bergman, Andries M., Severson, Tesa M., Forster, Colleen, Liu, Yuzhen, Hildebrand, Jacob, Daniel, Mark, Wang, Ting-You, Selth, Luke A., Hickey, Theresa, Zoubeidi, Amina, Gleave, Martin, Bareja, Rohan, Sboner, Andrea, Tilley, Wayne, Carroll, Jason S., Tan, Winston, Kohli, Manish, Yang, Rendong, Hsieh, Andrew C., Murugan, Paari, Zwart, Wilbert, Beltran, Himisha, Huang, R. Stephanie, Dehm, Scott M.

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Multi-level functional genomics reveals molecular and cellular oncogenicity of patient-based 3′ untranslated region mutations von Schuster, Samantha L., Arora, Sonali, Wladyka, Cynthia L., Itagi, Pushpa, Corey, Lukas, Young, Dave, Stackhouse, Bethany L., Kollath, Lori, Wu, Qian V., Corey, Eva, True, Lawrence D., Ha, Gavin, Paddison, Patrick J., Hsieh, Andrew C.

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ELAC2 is a functional prostate cancer risk allele von Blinka, Steven, Mishra, Rashmi, Hsieh, Andrew C.

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Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors von Hsieh, Andrew C, Nguyen, Hao G, Wen, Lexiaochuan, Edlind, Merritt P, Carroll, Peter R, Kim, Won, Ruggero, Davide

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Patterns of chemotherapy use with primary radiotherapy for localized bladder cancer in patients 65 or older von Ghali, Fady, Holt, Sarah K, Koehne, Elizabeth L, Chen, Jonathan J, Weg, Emily S, Liao, Jay J, Zeng, Jing, Grivas, Petros, Hawley, Jessica E, Hsieh, Andrew C, Montgomery, Robert Bruce, Wright, Jonathan L

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Defining cellular population dynamics at single-cell resolution during prostate cancer progression von Germanos, Alexandre A, Arora, Sonali, Zheng, Ye, Goddard, Erica T, Coleman, Ilsa M, Ku, Anson T, Wilkinson, Scott, Song, Hanbing, Brady, Nicholas J, Amezquita, Robert A, Zager, Michael, Long, Annalysa, Yang, Yu Chi, Bielas, Jason H, Gottardo, Raphael, Rickman, David S, Huang, Franklin W, Ghajar, Cyrus M, Nelson, Peter S, Sowalsky, Adam G, Setty, Manu, Hsieh, Andrew C

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Reciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis von Jana, Sujata, Hsieh, Andrew C, Gupta, Ramesh

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N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis von Kuppers, Daniel A., Arora, Sonali, Lim, Yiting, Lim, Andrea R., Carter, Lucas M., Corrin, Philip D., Plaisier, Christopher L., Basom, Ryan, Delrow, Jeffrey J., Wang, Shiyan, Hansen He, Housheng, Torok-Storb, Beverly, Hsieh, Andrew C., Paddison, Patrick J.

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Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling von Bluemn, Eric G., Coleman, Ilsa M., Lucas, Jared M., Coleman, Roger T., Hernandez-Lopez, Susana, Tharakan, Robin, Bianchi-Frias, Daniella, Dumpit, Ruth F., Kaipainen, Arja, Corella, Alexandra N., Yang, Yu Chi, Nyquist, Michael D., Mostaghel, Elahe, Hsieh, Andrew C., Zhang, Xiaotun, Corey, Eva, Brown, Lisha G., Nguyen, Holly M., Pienta, Kenneth, Ittmann, Michael, Schweizer, Michael, True, Lawrence D., Wise, David, Rennie, Paul S., Vessella, Robert L., Morrissey, Colm, Nelson, Peter S.

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