Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets von Howes, Joanna-Marie, Harper, Matthew T

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Cleavage by MMP‐13 renders VWF unable to bind to collagen but increases its platelet reactivity von Howes, Joanna‐Marie, Knäuper, Vera, Malcor, Jean‐Daniel, Farndale, Richard W.

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MMP‐13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation von Howes, Joanna‐Marie, Pugh, Nicholas, Hamaia, Samir W., Jung, Stephanie M., Knäuper, Vera, Malcor, Jean‐Daniel, Farndale, Richard W.

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The recognition of collagen and triple-helical toolkit peptides by MMP-13: sequence specificity for binding and cleavage von Howes, Joanna-Marie, Bihan, Dominique, Slatter, David A, Hamaia, Samir W, Packman, Len C, Knauper, Vera, Visse, Robert, Farndale, Richard W

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Constitutive Dimerization of Glycoprotein VI (GPVI) in Resting Platelets Is Essential for Binding to Collagen and Activation in Flowing Blood von Jung, Stephanie M., Moroi, Masaaki, Soejima, Kenji, Nakagaki, Tomohiro, Miura, Yoshiki, Berndt, Michael C., Gardiner, Elizabeth E., Howes, Joanna-Marie, Pugh, Nicholas, Bihan, Dominique, Watson, Steve P., Farndale, Richard W.

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Zinc is a transmembrane agonist that induces platelet activation in a tyrosine phosphorylation-dependent manner von Watson, Ben R, White, Nathan A, Taylor, Kirk A, Howes, Joanna-Marie, Malcor, Jean-Daniel M, Bihan, Dominique, Sage, Stewart O, Farndale, Richard W, Pugh, Nicholas

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Complement C3 is a novel plasma clot component with anti-fibrinolytic properties von Howes, Joanna-Marie, Richardson, Victoria R, Smith, Kerrie A, Schroeder, Verena, Somani, Riyaz, Shore, Anna, Hess, Katharina, Ajjan, Ramzi, Pease, Richard J, Keen, Jeffrey N, Standeven, Kristina F, Carter, Angela M

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The application of proteomics technology to thrombosis research: the identification of potential therapeutic targets in cardiovascular disease von Howes, Joanna-Marie, Keen, Jeff N, Findlay, John BC, Carter, Angela M

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The Recognition of Collagen and Triple-helical Toolkit Peptides by MMP-13 von Howes, Joanna-Marie, Bihan, Dominique, Slatter, David A., Hamaia, Samir W., Packman, Len C., Knauper, Vera, Visse, Robert, Farndale, Richard W.

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Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets von Howes, Joanna-Marie, Harper, Matthew T

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MMP ‐13 binds to platelet receptors α II bβ3 and GPVI and impairs aggregation and thrombus formation von Joanna‐Marie Howes, Pugh, Nicholas, Hamaia, Samir W, Jung, Stephanie M, Knäuper, Vera, Jean‐Daniel Malcor, Farndale, Richard W

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Application of the Cellular Thermal Shift Assay (CETSA) to validate drug target engagement in platelets von Howes, Joanna-Marie, Harper, Matthew T

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MMP-13 binds to platelet receptors αIIbβ3 and GPVI and impairs aggregation and thrombus formation von Howes, Joanna-Marie, Pugh, Nicholas, Hamaia, Samir W, Jung, Stephanie M, Knäuper, Vera, Malcor, Jean-Daniel, Farndale, Richard W

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The recognition of collagen and triple-helical toolkit peptides by MMP-13: sequence specificity for binding and cleavage von Howes, Joanna-Marie, Bihan, Dominique, Slatter, David A, Hamaia, Samir W, Packman, Len C, Knauper, Vera, Visse, Robert, Farndale, Richard W

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