Extending the application of biocatalysis to meet the challenges of drug development von Devine, Paul N., Howard, Roger M., Kumar, Rajesh, Thompson, Matthew P., Truppo, Matthew D., Turner, Nicholas J.

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Multifunctional biocatalyst for conjugate reduction and reductive amination von Thorpe, Thomas W., Marshall, James R., Harawa, Vanessa, Ruscoe, Rebecca E., Cuetos, Anibal, Finnigan, James D., Angelastro, Antonio, Heath, Rachel S., Parmeggiani, Fabio, Charnock, Simon J., Howard, Roger M., Kumar, Rajesh, Daniels, David S. B., Grogan, Gideon, Turner, Nicholas J.

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Biocatalytic Routes to Enantiomerically Enriched Dibenz[c,e]azepines von France, Scott P., Aleku, Godwin A., Sharma, Mahima, Mangas‐Sanchez, Juan, Howard, Roger M., Steflik, Jeremy, Kumar, Rajesh, Adams, Ralph W., Slabu, Iustina, Crook, Robert, Grogan, Gideon, Wallace, Timothy W., Turner, Nicholas J.

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One-Pot Cascade Synthesis of Mono- and Disubstituted Piperidines and Pyrrolidines using Carboxylic Acid Reductase (CAR), ω‑Transaminase (ω-TA), and Imine Reductase (IRED) Biocataly... von France, Scott P, Hussain, Shahed, Hill, Andrew M, Hepworth, Lorna J, Howard, Roger M, Mulholland, Keith R, Flitsch, Sabine L, Turner, Nicholas J

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One-Pot Biocatalytic Cascade Reduction of Cyclic Enimines for the Preparation of Diastereomerically Enriched N‑Heterocycles von Thorpe, Thomas W, France, Scott P, Hussain, Shahed, Marshall, James R, Zawodny, Wojciech, Mangas-Sanchez, Juan, Montgomery, Sarah L, Howard, Roger M, Daniels, David S. B, Kumar, Rajesh, Parmeggiani, Fabio, Turner, Nicholas J

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Probing the chemical ‘reactome’ with high-throughput experimentation data von King-Smith, Emma, Berritt, Simon, Bernier, Louise, Hou, Xinjun, Klug-McLeod, Jacquelyn L., Mustakis, Jason, Sach, Neal W., Tucker, Joseph W., Yang, Qingyi, Howard, Roger M., Lee, Alpha A.

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Cell‐free in vitro reduction of carboxylates to aldehydes: With crude enzyme preparations to a key pharmaceutical building block von Schwarz, Anna, Hecko, Sebastian, Rudroff, Florian, Kohrt, Jeffrey T., Howard, Roger M., Winkler, Margit

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Identification of Novel Bacterial Members of the Imine Reductase Enzyme Family that Perform Reductive Amination von France, Scott P., Howard, Roger M., Steflik, Jeremy, Weise, Nicholas J., Mangas‐Sanchez, Juan, Montgomery, Sarah L., Crook, Robert, Kumar, Rajesh, Turner, Nicholas J.

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A Reductive Aminase Switches to Imine Reductase Mode for a Bulky Amine Substrate von Gilio, Amelia K., Thorpe, Thomas W., Heyam, Alex, Petchey, Mark R., Pogrányi, Balázs, France, Scott P., Howard, Roger M., Karmilowicz, Michael J., Lewis, Russell, Turner, Nicholas, Grogan, Gideon

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Parallel multi-droplet platform for reaction kinetics and optimization von Eyke, Natalie S, Schneider, Timo N, Jin, Brooke, Hart, Travis, Monfette, Sebastien, Hawkins, Joel M, Morse, Peter D, Howard, Roger M, Pfisterer, David M, Nandiwale, Kakasaheb Y, Jensen, Klavs F

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PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease von Gopalsamy, Ariamala, Aulabaugh, Ann E, Barakat, Amey, Beaumont, Kevin C, Cabral, Shawn, Canterbury, Daniel P, Casimiro-Garcia, Agustin, Chang, Jeanne S, Chen, Ming Z, Choi, Chulho, Dow, Robert L, Fadeyi, Olugbeminiyi O, Feng, Xidong, France, Scott P, Howard, Roger M, Janz, Jay M, Jasti, Jayasankar, Jasuja, Reema, Jones, Lyn H, King-Ahmad, Amanda, Knee, Kelly M, Kohrt, Jeffrey T, Limberakis, Chris, Liras, Spiros, Martinez, Carlos A, McClure, Kim F, Narayanan, Arjun, Narula, Jatin, Novak, Jonathan J, O'Connell, Thomas N, Parikh, Mihir D, Piotrowski, David W, Plotnikova, Olga, Robinson, Ralph P, Sahasrabudhe, Parag V, Sharma, Raman, Thuma, Benjamin A, Vasa, Dipy, Wei, Liuqing, Wenzel, A Zane, Withka, Jane M, Xiao, Jun, Yayla, Hatice G

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Scalable, Telescoped Hydrogenolysis–Enzymatic Decarboxylation Process for the Asymmetric Synthesis of (R)‑α-Heteroaryl Propionic Acids von Blakemore, Caroline A, France, Scott P, Samp, Lacey, Nason, Deane M, Yang, Eddie, Howard, Roger M, Coffman, Karen J, Yang, Qingyi, Smith, Aaron C, Evrard, Edelweiss, Li, Wei, Dai, Linlin, Yang, Lixia, Chen, Zhiguang, Zhang, Qingli, He, Fangyan, Zhang, Jiesen

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Operator-free HPLC automated method development guided by Bayesian optimization von Dixon, Thomas M, Williams, Jeanine, Besenhard, Maximilian, Howard, Roger M, MacGregor, James, Peach, Philip, Clayton, Adam D, Warren, Nicholas J, Bourne, Richard A

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Improving Transnational Education in Timber Construction by the Use of Project-Based Learning Approach: As Evaluated by Teachers and Students von Mortesen, Andrea, Tupenaite, Laura, Naimaviciene, Jurga, Kanapeckiene, Loreta, Amado, Miguel, Hamburg, Pille, Taylor, Roger Howard

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Dangers of applying fan manufacturer data to equipment sound ratings von Bauch, Paul F., Howard, Roger L.

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Preparative access to medicinal chemistry related chiral alcohols using carbonyl reductase technology von Rowan, Andrew S., Moody, Thomas S., Howard, Roger M., Underwood, Toby J., Miskelly, Iain R., He, Yanan, Wang, Bo

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Application of biocatalysis towards asymmetric reduction and hydrolytic desymmetrisation in the synthesis of a β-3 receptor agonist von BADLAND, Matthew, BURNS, Michael P, CARROLL, Robert J, HOWARD, Roger M, LAITY, Daniel, WYMER, Nathan J

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The use of environmental metrics to evaluate green chemistry improvements to the synthesis of (S,S)-reboxetine succinate von Assaf, Georges, Checksfield, Graham, Critcher, Doug, Dunn, Peter J, Field, Stuart, Harris, Laurence J, Howard, Roger M, Scotney, Gemma, Scott, Adam, Mathew, Suju, Walker, Geoffrey M. H, Wilder, Alexander

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Development of an Asymmetric Hydrogenation Route to (S)-N-Boc-2,6-dimethyltyrosine von Praquin, Céline F. B, de Koning, Pieter D, Peach, Philip J, Howard, Roger M, Spencer, Sarah L

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Iran Oil: The New Middle East Challenge to America von Howard, Roger

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