Abstract 16612: Cardiomyocyte PGC-1α Prevents Cardiac Atrophy and Failure in Response to Endurance Exercise Training von Khetarpal, Sumeet, LI, Haobo, Castro, Claire, Houstis, Nicholas A, Rhee, James, Sprenger, Hans-Georg, Mittenbuhler, Melanie, Kuznetsov, Alexandra, Freeman, Rebecca, Asnani, Aarti, Dumesic, Phillip, Roh, Jason D, Rosenzweig, Anthony, Spiegelman, Bruce

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Why Don’t We Have Proven Treatments for HFpEF? von Roh, Jason, Houstis, Nicholas, Rosenzweig, Anthony

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Cardiac macrophages promote diastolic dysfunction von Hulsmans, Maarten, Sager, Hendrik B, Roh, Jason D, Valero-Muñoz, María, Houstis, Nicholas E, Iwamoto, Yoshiko, Sun, Yuan, Wilson, Richard M, Wojtkiewicz, Gregory, Tricot, Benoit, Osborne, Michael T, Hung, Judy, Vinegoni, Claudio, Naxerova, Kamila, Sosnovik, David E, Zile, Michael R, Bradshaw, Amy D, Liao, Ronglih, Tawakol, Ahmed, Weissleder, Ralph, Rosenzweig, Anthony, Swirski, Filip K, Sam, Flora, Nahrendorf, Matthias

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Physical activity and fitness in the community: the Framingham Heart Study von Nayor, Matthew, Chernofsky, Ariel, Spartano, Nicole L, Tanguay, Melissa, Blodgett, Jasmine B, Murthy, Venkatesh L, Malhotra, Rajeev, Houstis, Nicholas E, Velagaleti, Raghava S, Murabito, Joanne M, Larson, Martin G, Vasan, Ramachandran S, Shah, Ravi V, Lewis, Gregory D

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Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Diagnosing and Ranking Its Causes Using Personalized O 2 Pathway Analysis von Houstis, Nicholas E, Eisman, Aaron S, Pappagianopoulos, Paul P, Wooster, Luke, Bailey, Cole S, Wagner, Peter D, Lewis, Gregory D

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Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Diagnosing and Ranking Its Causes Using Personalized O2 Pathway Analysis von Houstis, Nicholas E, Eisman, Aaron S, Pappagianopoulos, Paul P, Wooster, Luke, Bailey, Cole S, Wagner, Peter D, Lewis, Gregory D

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Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community von Nayor, Matthew, Shah, Ravi V., Miller, Patricia E., Blodgett, Jasmine B., Tanguay, Melissa, Pico, Alexander R., Murthy, Venkatesh L., Malhotra, Rajeev, Houstis, Nicholas E., Deik, Amy, Pierce, Kerry A., Bullock, Kevin, Dailey, Lucas, Velagaleti, Raghava S., Moore, Stephanie A., Ho, Jennifer E., Baggish, Aaron L., Clish, Clary B., Larson, Martin G., Vasan, Ramachandran S., Lewis, Gregory D.

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The Adipokine Lipocalin 2 Is Regulated by Obesity and Promotes Insulin Resistance von YAN, Qing-Wu, QIN YANG, MODY, Nimesh, GRAHAM, Timothy E, HSU, Chung-Hsin, ZHAO XU, HOUSTIS, Nicholas E, KAHN, Barbara B, ROSEN, Evan D

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Mechanisms of exercise intolerance in heart failure with preserved ejection fraction: the role of abnormal peripheral oxygen extraction von Dhakal, Bishnu P, Malhotra, Rajeev, Murphy, Ryan M, Pappagianopoulos, Paul P, Baggish, Aaron L, Weiner, Rory B, Houstis, Nicholas E, Eisman, Aaron S, Hough, Stacyann S, Lewis, Gregory D

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Exercise Pulmonary Hypertension Predicts Clinical Outcomes in Patients With Dyspnea on Effort von Ho, Jennifer E., Zern, Emily K., Lau, Emily S., Wooster, Luke, Bailey, Cole S., Cunningham, Thomas, Eisman, Aaron S., Hardin, Kathryn M., Farrell, Robyn, Sbarbaro, John A., Schoenike, Mark W., Houstis, Nicholas E., Baggish, Aaron L., Shah, Ravi V., Nayor, Matthew, Malhotra, Rajeev, Lewis, Gregory D.

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Impaired Exercise Tolerance in Heart Failure With Preserved Ejection Fraction: Quantification of Multiorgan System Reserve Capacity von Nayor, Matthew, Houstis, Nicholas E, Namasivayam, Mayooran, Rouvina, Jennifer, Hardin, Charles, Shah, Ravi V, Ho, Jennifer E, Malhotra, Rajeev, Lewis, Gregory D

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Reactive oxygen species have a causal role in multiple forms of insulin resistance von Houstis, Nicholas, Rosen, Evan D, Lander, Eric S

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Using Exercise to Measure and Modify Cardiac Function von Platt, Colin, Houstis, Nicholas, Rosenzweig, Anthony

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Animal Models of Exercise From Rodents to Pythons von Hastings, Margaret H., Herrera, Jonathan J., Guseh, J. Sawalla, Atlason, Bjarni, Houstis, Nicholas E., Abdul Kadir, Azrul, Li, Haobo, Sheffield, Cedric, Singh, Anand P., Roh, Jason D., Day, Sharlene M., Rosenzweig, Anthony

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Arterial Stiffness and Cardiorespiratory Fitness Impairment in the Community von Nayor, Matthew, Gajjar, Priya, Miller, Patricia, Murthy, Venkatesh L, Shah, Ravi V, Houstis, Nicholas E, Velagaleti, Raghava S, Larson, Martin G, Vasan, Ramachandran S, Lewis, Gregory D, Mitchell, Gary F

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Decoding the Pathophysiology of HFpEF With High-Resolution Phenotyping von Houstis, Nicholas E.

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Clinical and Hemodynamic Associations and Prognostic Implications of Ventilatory Efficiency in Patients With Preserved Left Ventricular Systolic Function von Nayor, Matthew, Xanthakis, Vanessa, Tanguay, Melissa, Blodgett, Jasmine B., Shah, Ravi V., Schoenike, Mark, Sbarbaro, John, Farrell, Robyn, Malhotra, Rajeev, Houstis, Nicholas E., Velagaleti, Raghava S., Moore, Stephanie A., Baggish, Aaron L., O’Connor, George T., Ho, Jennifer E., Larson, Martin G., Vasan, Ramachandran S., Lewis, Gregory D.

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Feasibility, Methodology, and Interpretation of Broad-Scale Assessment of Cardiorespiratory Fitness in a Large Community-Based Sample von Nayor, Matthew, Shah, Ravi V., Tanguay, Melissa, Blodgett, Jasmine B., Chernofsky, Ariel, Miller, Patricia E., Xanthakis, Vanessa, Malhotra, Rajeev, Houstis, Nicholas E., Velagaleti, Raghava S., Larson, Martin G., Vasan, Ramachandran S., Lewis, Gregory D.

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Causes of Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Searching for Consensus von Houstis, Nicholas E., MD, PhD, Lewis, Gregory D., MD

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An expanded repertoire of intensity-dependent exercise-responsive plasma proteins tied to loci of human disease risk von Guseh, J. Sawalla, Churchill, Timothy W., Yeri, Ashish, Lo, Claire, Brown, Marcel, Houstis, Nicholas E., Aragam, Krishna G., Lieberman, Daniel E., Rosenzweig, Anthony, Baggish, Aaron L.

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