Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins von Wang, Eric T., Cody, Neal A.L., Jog, Sonali, Biancolella, Michela, Wang, Thomas T., Treacy, Daniel J., Luo, Shujun, Schroth, Gary P., Housman, David E., Reddy, Sita, Lécuyer, Eric, Burge, Christopher B.

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Tenofovir prodrugs potently inhibit Epstein–Barr virus lytic DNA replication by targeting the viral DNA polymerase von Drosu, Natalia C., Edelman, Elazer R., Housman, David E.

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Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits von Lim, Ryan G., Quan, Chris, Reyes-Ortiz, Andrea M., Lutz, Sarah E., Kedaigle, Amanda J., Gipson, Theresa A., Wu, Jie, Vatine, Gad D., Stocksdale, Jennifer, Casale, Malcolm S., Svendsen, Clive N., Fraenkel, Ernest, Housman, David E., Agalliu, Dritan, Thompson, Leslie M.

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Potential function for the Huntingtin protein as a scaffold for selective autophagy von Ochaba, Joseph, Lukacsovich, Tamás, Csikos, George, Zheng, Shuqiu, Margulis, Julia, Salazar, Lisa, Mao, Kai, Lau, Alice L., Yeung, Sylvia Y., Humbert, Sandrine, Saudou, Frédéric, Klionsky, Daniel J., Finkbeiner, Steven, Zeitlin, Scott O., Marsh, J. Lawrence, Housman, David E., Thompson, Leslie M., Steffan, Joan S.

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Striosome–dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons von Crittenden, Jill R., Tillberg, Paul W., Riad, Michael H., Shima, Yasuyuki, Gerfen, Charles R., Curry, Jeffrey, Housman, David E., Nelson, Sacha B., Boyden, Edward S., Graybiel, Ann M.

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Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells von Williams, Bret R., Prabhu, Vineet R., Hunter, Karen E., Glazier, Christina M., Whittaker, Charles A., Housman, David E., Amon, Angelika

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Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease von Sathasivam, Kirupa, Neueder, Andreas, Gipson, Theresa A., Landles, Christian, Benjamin, Agnesska C., Bondulich, Marie K., Smith, Donna L., Faull, Richard L. M., Roos, Raymund A. C., Howland, David, Detloff, Peter J., Housman, David E., Bates, Gillian P.

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Extensive changes in DNA methylation are associated with expression of mutant huntingtin von Ng, Christopher W., Yildirim, Ferah, Yap, Yoon Sing, Dalin, Simona, Matthews, Bryan J., Velez, Patricio J., Labadorf, Adam, Housman, David E., Fraenkel, Ernest

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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila von Thompson, Leslie M, Steffan, Joan S, Bodai, Laszlo, Pallos, Judit, Poelman, Marnix, McCampbell, Alexander, Apostol, Barbara L, Kazantsev, Alexsey, Schmidt, Emily, Zhu, Ya-Zhen, Greenwald, Marilee, Kurokawa, Riki, Housman, David E, Jackson, George R, Marsh, J. Lawrence

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A Potent Small Molecule Inhibits Polyglutamine Aggregation in Huntington's Disease Neurons and Suppresses Neurodegeneration in vivo von Zhang, Xiaoqian, Smith, Donna L., Meriin, Anatoli B., Engemann, Sabine, Russel, Deborah E., Roark, Margo, Washington, Shetia L., Maxwell, Michele M., Marsh, J. Lawrence, Thompson, Leslie Michels, Wanker, Erich E., Young, Anne B., Housman, David E., Bates, Gillian P., Sherman, Michael Y., Kazantsev, Aleksey G.

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Targeting H3K4 trimethylation in Huntington disease von Vashishtha, Malini, Ng, Christopher W, Yildirim, Ferah, Gipson, Theresa A, Kratter, Ian H, Bodai, Laszlo, Song, Wan, Lau, Alice, Labadorf, Adam, Vogel-Ciernia, Annie, Troncosco, Juan, Ross, Christopher A, Bates, Gillian P, Krainc, Dimitri, Sadri-Vakili, Ghazaleh, Finkbeiner, Steven, Marsh, J Lawrence, Housman, David E, Fraenkel, Ernest, Thompson, Leslie M

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Multi-omic analysis of Huntington’s disease reveals a compensatory astrocyte state von Paryani, Fahad, Kwon, Ji-Sun, Ng, Christopher W., Jakubiak, Kelly, Madden, Nacoya, Ofori, Kenneth, Tang, Alice, Lu, Hong, Xia, Shengnan, Li, Juncheng, Mahajan, Aayushi, Davidson, Shawn M., Basile, Anna O., McHugh, Caitlin, Vonsattel, Jean Paul, Hickman, Richard, Zody, Michael C., Housman, David E., Goldman, James E., Yoo, Andrew S., Menon, Vilas, Al-Dalahmah, Osama

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Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis von Zhu, Haihao, Acquaviva, Jaime, Ramachandran, Pranatartiharan, Boskovitz, Abraham, Woolfenden, Steve, Pfannl, Rolf, Bronson, Roderick T, Chen, John W, Weissleder, Ralph, Housman, David E, Charest, Al

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mTORC1 Promotes Survival through Translational Control of Mcl-1 von Mills, John R., Hippo, Yoshitaka, Robert, Francis, Chen, Samuel M. H., Malina, Abba, Lin, Chen-Ju, Trojahn, Ulrike, Wendel, Hans-Guido, Charest, Al, Bronson, Roderick T., Kogan, Scott C., Nadon, Robert, Housman, David E., Lowe, Scott W., Pelletier, Jerry

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A Family of cAMP-Binding Proteins That Directly Activate Rap1 von Kawasaki, Hiroaki, Springett, Gregory M., Mochizuki, Naoki, Toki, Shinichiro, Nakaya, Mie, Matsuda, Michiyuki, Housman, David E., Graybiel, Ann M.

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Pharmacological Promotion of Inclusion Formation: A Therapeutic Approach for Huntington's and Parkinson's Diseases von Bodner, Ruth A., Outeiro, Tiago Fleming, Altmann, Stephen, Maxwell, Michele M., Cho, Stephanie H., Hyman, Bradley T., McLean, Pamela J., Young, Anne B., Housman, David E., Kazantsev, Aleksey G.

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CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors von Crittenden, Jill R., Zhai, Shenyu, Sauvage, Magdalena, Kitsukawa, Takashi, Burguière, Eric, Thomsen, Morgane, Zhang, Hui, Costa, Cinzia, Martella, Giuseppina, Ghiglieri, Veronica, Picconi, Barbara, Pescatore, Karen A., Unterwald, Ellen M., Jackson, Walker S., Housman, David E., Caine, S. Barak, Sulzer, David, Calabresi, Paolo, Smith, Anne C., Surmeier, D. James, Graybiel, Ann M.

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The Huntington's Disease Protein Interacts with p53 and CREB-Binding Protein and Represses Transcription von Steffan, Joan S., Kazantsev, Aleksey, Spasic-Boskovic, Olivera, Greenwald, Marilee, Zhu, Ya-Zhen, Gohler, Heike, Wanker, Erich E., Bates, Gillian P., Housman, David E., Thompson, Leslie M.

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Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice von Crook, Zachary R., Housman, David E.

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Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme von Jun, H J, Acquaviva, J, Chi, D, Lessard, J, Zhu, H, Woolfenden, S, Bronson, R T, Pfannl, R, White, F, Housman, D E, Iyer, L, Whittaker, C A, Boskovitz, A, Raval, A, Charest, A

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