The value of antimicrobial peptides in the age of resistance von Magana, Maria, Pushpanathan, Muthuirulan, Santos, Ana L, Leanse, Leon, Fernandez, Michael, Ioannidis, Anastasios, Giulianotti, Marc A, Apidianakis, Yiorgos, Bradfute, Steven, Ferguson, Andrew L, Cherkasov, Artem, Seleem, Mohamed N, Pinilla, Clemencia, de la Fuente-Nunez, Cesar, Lazaridis, Themis, Dai, Tianhong, Houghten, Richard A, Hancock, Robert E W, Tegos, George P

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Shifting from the single to the multitarget paradigm in drug discovery von Medina-Franco, José L., Giulianotti, Marc A., Welmaker, Gregory S., Houghten, Richard A.

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Mu-Opioid receptor biased ligands: A safer and painless discovery of analgesics? von Madariaga-Mazón, Abraham, Marmolejo-Valencia, Andrés F., Li, Yangmei, Toll, Lawrence, Houghten, Richard A., Martinez-Mayorga, Karina

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Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide von Li, Yangmei, Eans, Shainnel O, Ganno-Sherwood, Michelle, Eliasof, Abbe, Houghten, Richard A, McLaughlin, Jay P

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The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (M... von Ericson, Mark D, Freeman, Katie T, LaVoi, Travis M, Donow, Haley M, Santos, Radleigh G, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Haskell-Luevano, Carrie

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Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products, and Molecular Libraries Small Molecule Repository von Singh, Narender, Guha, Rajarshi, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Medina-Franco, Jose L

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Discovery of Novel Inhibitors of a Disintegrin and Metalloprotease 17 (ADAM17) Using Glycosylated and Non-glycosylated Substrates von Minond, Dmitriy, Cudic, Mare, Bionda, Nina, Giulianotti, Marc, Maida, Laura, Houghten, Richard A., Fields, Gregg B.

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Identification of a Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens von Fleeman, Renee M, Debevec, Ginamarie, Antonen, Kirsten, Adams, Jessie L, Santos, Radleigh G, Welmaker, Gregory S, Houghten, Richard A, Giulianotti, Marc A, Shaw, Lindsey N

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Activity of ADAM17 (a Disintegrin and Metalloprotease 17) Is Regulated by Its Noncatalytic Domains and Secondary Structure of its Substrates von Stawikowska, Roma, Cudic, Mare, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy

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Novel Cyclic Lipopeptides Fusaricidin Analogs for Treating Wound Infections von Gil, Joel, Pastar, Irena, Houghten, Richard A., Padhee, Shruti, Higa, Alexander, Solis, Michael, Valdez, Jose, Head, Cheyanne R., Michaels, Heather, Lenhart, Brian, Simms, Colin, Williams, Brandon, Cudic, Predrag, Davis, Stephen C.

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A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery von Palrasu, Manikandan, Knapinska, Anna M, Diez, Juan, Smith, Lyndsay, LaVoi, Travis, Giulianotti, Marc, Houghten, Richard A, Fields, Gregg B, Minond, Dmitriy

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Palladium-Catalyzed C–H Functionalization Using Guanidine as a Directing Group: Ortho Arylation and Olefination of Arylguanidines von Shao, Jiaan, Chen, Wenteng, Giulianotti, Marc A, Houghten, Richard A, Yu, Yongping

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity von Schimmer, Aaron D., Welsh, Kate, Pinilla, Clemencia, Wang, Zhiliang, Krajewska, Maryla, Bonneau, Marie-Josee, Pedersen, Irene M., Kitada, Shinichi, Scott, Fiona L., Bailly-Maitre, Beatrice, Glinsky, Gennadi, Scudiero, Dominick, Sausville, Edward, Salvesen, Guy, Nefzi, Adel, Ostresh, John M., Houghten, Richard A., Reed, John C.

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A traceless approach to amide and peptide construction from thioacids and dithiocarbamate-terminal amines von Chen, Wenteng, Shao, Jiaan, Hu, Miao, Yu, Wanwan, Giulianotti, Marc A, Houghten, Richard A, Yu, Yongping

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The Current Status of Heterocyclic Combinatorial Libraries von Nefzi, Adel, Ostresh, John M, Houghten, Richard A

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Short Polybasic Peptide Sequences Are Potent Inhibitors of PC5/6 and PC7: Use of Positional Scanning-Synthetic Peptide Combinatorial Libraries as a Tool for the Optimization of Inh... von Fugere, Martin, Appel, Jon, Houghten, Richard A, Lindberg, Iris, Day, Robert

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Combinatorial Chemistry:  Libraries from Libraries, the Art of the Diversity-Oriented Transformation of Resin-Bound Peptides and Chiral Polyamides to Low Molecular Weight Acyclic a... von Nefzi, Adel, Ostresh, John M, Yu, Jongping, Houghten, Richard A

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Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells von Carter, Bing Z., Gronda, Marcela, Wang, Zhiliang, Welsh, Kate, Pinilla, Clemencia, Andreeff, Michael, Schober, Wendy D., Nefzi, Adel, Pond, Gregory R., Mawji, Imtiaz A., Houghten, Richard A., Ostresh, John, Brandwein, Joseph, Minden, Mark D., Schuh, Andre C., Wells, Richard A., Messner, Hans, Chun, Kathy, Reed, John C., Schimmer, Aaron D.

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Mixture-Based Synthetic Combinatorial Libraries von Houghten, Richard A, Pinilla, Clemencia, Appel, Jon R, Blondelle, Sylvie E, Dooley, Colette T, Eichler, Jutta, Nefzi, Adel, Ostresh, John M

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The mathematics of a successful deconvolution: a quantitative assessment of mixture-based combinatorial libraries screened against two formylpeptide receptors von Santos, Radleigh G, Appel, Jon R, Giulianotti, Marc A, Edwards, Bruce S, Sklar, Larry A, Houghten, Richard A, Pinilla, Clemencia

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