Structure and Functional Characterization of a Humanized Anti-CCL20 Antibody following Exposure to Serum Reveals the Formation of Immune Complex That Leads to Toxicity von Thomson, Andrew S., Mai, Shing H., Bouma, Gerben, Herdman, Michael, Byrne, Michael, Hottenstein, Charles S., Minetti, Joseph, Trulli, Stephen, Taylor, J. David, White, John R., Chen, Shugui

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Native high-resolution mass spectrometry analysis of noncovalent protein complexes up to 450 kDa von Chen, Zhuo, Kellie, John F., Hottenstein, Charles S., Szapacs, Matthew E.

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Ligand-Binding Assay Development: What Do You Want to Measure Versus What You Are Measuring? von Mayer, Andrew P., Hottenstein, Charles S.

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A Whole-Molecule Immunocapture LC–MS Approach for The In Vivo Quantitation of Biotherapeutics von Kellie, John F, Kehler, Jonathan R, Mencken, Thomas J, Snell, Richard J, Hottenstein, Charles S

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Bioanalytical challenges and unique considerations to support pharmacokinetic characterization of bispecific biotherapeutics von Ma, Mark, Colletti, Kelly, Yang, Tong-Yuan, Leung, Sheldon, Pederson, Susan, Hottenstein, Charles S, Xu, Xiaohui, Warrino, Dominic, Wakshull, Eric

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The Gyrolab™ Immunoassay System: A Platform for Automated Bioanalysis and Rapid Sample Turnaround von Fraley, Kristy J, Abberley, Lee, Hottenstein, Charles S, Ulicne, John J, Citerone, David R, Szapacs, Matthew E

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Comparison of Titer and Signal to Noise (S/N) for Determination of Anti-drug Antibody Magnitude Using Clinical Data from an Industry Consortium von Starcevic Manning, Marta, Hassanein, Mohamed, Partridge, Michael A., Jawa, Vibha, Mora, Johanna, Ryman, Josiah, Barker, Breann, Braithwaite, Christian, Carleton, Kevin, Hay, Laura, Hottenstein, Charles, Kubiak, Robert J., Devanarayan, Viswanath

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Anti-drug Antibody Validation Testing and Reporting Harmonization von Myler, Heather, Pedras-Vasconcelos, João, Phillips, Kelli, Hottenstein, Charles Scott, Chamberlain, Paul, Devanaryan, Viswanath, Gleason, Carol, Goodman, Joanne, Manning, Marta Starcevic, Purushothama, Shobha, Richards, Susan, Shen, Honglue, Zoghbi, Jad, Amaravadi, Lakshmi, Barger, Troy, Bowen, Steven, Bowsher, Ronald R., Clements-Egan, Adrienne, Geng, Dong, Goletz, Theresa J., Gunn, George R., Hallett, William, Hodsdon, Michael E., Janelsins, Brian M., Jawa, Vibha, Kamondi, Szilard, Kirshner, Susan, Kramer, Daniel, Liang, Meina, Lindley, Kathryn, Liu, Susana, Liu, ZhenZhen, McNally, Jim, Mikulskis, Alvydas, Nelson, Robert, Ahbari, Mohsen Rajabi, Qu, Qiang, Ruppel, Jane, Snoeck, Veerle, Song, An, Yan, Haoheng, Ware, Mark

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Platforms and techniques used for biomarker assays: where are we now? von Hottenstein, Charles, Szapacs, Matthew, Fuller, Kerensa, Evans, Christopher

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2018 White Paper on Recent Issues in Bioanalysis: ‘A Global Bioanalytical Community Perspective on Last Decade of Incurred Samples Reanalysis (ISR)’ (Part 1 – Small Molecule Regula... von Welink, Jan, Xu, Yuanxin, Yang, Eric, Wilson, Amanda, Henderson, Neil, Luo, Lina, Fraser, Stephanie, Kavita, Uma, Musuku, Adrien, James, Christopher, Fraier, Daniela, Zhang, Yan, Goykhman, Dina, Summerfield, Scott, Woolf, Eric, Verhaeghe, Tom, Hughes, Nicola, Behling, Alexander, Brown, Kirk, Bulychev, Alex, Buonarati, Michael, Cherry, Elana, Cho, Seongeun (Julia), Cludts, Isabelle, Dillen, Lieve, Dodge, Robert, Edmison, Anna, Garofolo, Fabio, Green, Rachel, Haidar, Sam, Hottenstein, Charles, Ishii-Watabe, Akiko, Jang, Hyun Gyung, Ji, Allena, Jones, Barry, Kassim, Sean, Ma, Mark, Meena, Lima Santos, Gustavo Mendes, Norris, Daniel A, Owen, Tate, Piccoli, Steven, Ramanathan, Ragu, Röhl, Ingo, Rosenbaum, Anton I, Saito, Yoshiro, Sangster, Timothy, Savoie, Natasha, Stebbins, Christopher, Sydor, Jens, de Merbel, Nico van, Verthelyi, Daniela, Vinter, Stephen, Whale, Emma

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2016 White Paper on recent issues in bioanalysis: focus on biomarker assay validation (BAV): (Part 3 - LBA, biomarkers and immunogenicity) von Richards, Susan, Amaravadi, Lakshmi, Pillutla, Renuka, Birnboeck, Herbert, Torri, Albert, Cowan, Kyra J, Papadimitriou, Apollon, Garofolo, Fabio, Satterwhite, Christina, Piccoli, Steven, Wu, Bonnie, Krinos-Fiorotti, Corinna, Allinson, John, Berisha, Flora, Cocea, Laurent, Croft, Stephanie, Fraser, Stephanie, Galliccia, Fabrizio, Gorovits, Boris, Gupta, Swati, Gupta, Vinita, Haidar, Sam, Hottenstein, Charles, Ishii-Watabe, Akiko, Jani, Darshana, Kadavil, John, Kamerud, John, Kramer, Daniel, Litwin, Virginia, Lima Santos, Gustavo Mendes, Nelson, Robert, Ni, Yan, Pedras-Vasconcelos, João, Qiu, Yongchang, Rhyne, Paul, Safavi, Afshin, Saito, Yoshiro, Savoie, Natasha, Scheibner, Kara, Schick, Eginhard, Siguenza, Patricia Y, Smeraglia, John, Staack, Roland F, Subramanyam, Meena, Sumner, Giane, Thway, Theingi, Uhlinger, David, Ullmann, Martin, Vitaliti, Alessandra, Welink, Jan, Whiting, Chan C, Xue, Li, Zeng, Rong

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A whole-molecule immunocapture LC-MS approach for the von Kellie, John F, Kehler, Jonathan R, Mencken, Thomas J, Snell, Richard J, Hottenstein, Charles S

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Determination of Pentachlorophenol in Water and Soil by a Magnetic Particle-Based Enzyme Immunoassay von Hottenstein, Charles S, Jourdan, Scott W, Hayes, Mary C, Rubio, Fernando M, Herzog, David P, Lawruk, Timothy S

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Modulation of β-amyloid by a single dose of GSK933776 in patients with mild Alzheimer's disease: a phase I study von Leyhe, Thomas, Andreasen, Niels, Simeoni, Monica, Reich, Arno, von Arnim, Christine Af, Tong, Xin, Yeo, Astrid, Khan, Shahid, Loercher, Amy, Chalker, Michelle, Hottenstein, Charles, Zetterberg, Henrik, Hilpert, Jan, Mistry, Prafull

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Assessment of the effect of ofatumumab on cardiac repolarization von Jewell, Roxanne C., Laubscher, Kevin, Lewis, Eric, Fang, Lei, Gafoor, Zarina, Carey, Jodi, McKeown, Astrid, West, Sarah, Wright, Oliver, Sedoti, Donna, Dixon, Iestyn, Hottenstein, Charles Scott, Chan, Geoffrey

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Determination of Trace Atrazine Levels in Water by a Sensitive Magnetic Particle-Based Enzyme Immunoassay von Hottenstein, Charles S, Rubio, Fernando M, Herzog, David P, Fleeker, James R, Lawruk, Timothy S

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2018 White Paper on Recent Issues in Bioanalysis von Welink, Jan, Xu, Yuanxin, Yang, Eric, Wilson, Amanda, Henderson, Neil, Luo, Lina, Fraser, Stephanie, Kavita, Uma, Musuku, Adrien, James, Christopher, Fraier, Daniela, Zhang, Yan, Goykhman, Dina, Summerfield, Scott, Woolf, Eric, Verhaeghe, Tom, Hughes, Nicola, Behling, Alexander, Brown, Kirk, Bulychev, Alex, Buonarati, Michael, Cherry, Elana, Cho, Seongeun (Julia), Cludts, Isabelle, Dillen, Lieve, Dodge, Robert, Edmison, Anna, Garofolo, Fabio, Green, Rachel, Haidar, Sam, Hottenstein, Charles, Ishii-Watabe, Akiko, Jang, Hyun Gyung, Ji, Allena, Jones, Barry, Kassim, Sean, Ma, Mark, Lima Santos, Gustavo Mendes, Norris, Daniel A, Owen, Tate, Piccoli, Steven, Ramanathan, Ragu, Röhl, Ingo, Rosenbaum, Anton I, Saito, Yoshiro, Sangster, Timothy, Savoie, Natasha, Stebbins, Christopher, Sydor, Jens, de Merbel, Nico van, Verthelyi, Daniela, Vinter, Stephen, Whale, Emma

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Modulation of [beta]-amyloid by a single dose of GSK933776 in patients with mild Alzheimer's disease: a phase I study von Leyhe, Thomas, Andreasen, Niels, Simeoni, Monica, Reich, Arno, von Arnim, Christine AF, Tong, Xin, Yeo, Astrid, Khan, Shahid, Loercher, Amy, Chalker, Michelle, Hottenstein, Charles, Zetterberg, Henrik, Hilpert, Jan, Mistry, Prafull

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Strategy and validation of a nonclinicalgeneric plug-and-play antidrug antibodymethod for human monoclonal antibodybiotherapeutics: supplementary tables von Polsky, Rodd, Gunn, George, J Reese, Kimberly, Scott Hottenstein, Charles, Gehman, Andrew, Schwartz, Ann, Root, Devin, Concannon, Amy

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Determination of Trace Atrazine Levels in Water by a Sensitive Magnetic Particle-Based Enzyme von Hottenstein, Charles S, Rubio, Fernando M, Herzog, David P, Fleeker, James R, Lawruk, Timothy S

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