A reassessment of copper(II) binding in the full-length prion protein von Wells, Mark A, Jackson, Graham S, Jones, Samantha, Hosszu, Laszlo L P, Craven, C Jeremy, Clarke, Anthony R, Collinge, John, Waltho, Jonathan P

Volltext

Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4 von Wells, Mark A, Jelinska, Clare, Hosszu, Laszlo L P, Craven, C Jeremy, Clarke, Anthony R, Collinge, John, Waltho, Jonathan P, Jackson, Graham S

Volltext

Folding kinetics of the human prion protein probed by temperature jump von Hart, Tanya, Hosszu, Laszlo L.P, Trevitt, Clare R, Jackson, Graham S, Waltho, Jonathan P, Collinge, John, Clarke, Anthony R

Volltext

Location and Properties of Metal-Binding Sites on the Human Prion Protein von Jackson, G S, Murray, I, Hosszu, L L, Gibbs, N, Waltho, J P, Clarke, A R, Collinge, J

Volltext

Characterization of Prion Disease Associated with a Two-Octapeptide Repeat Insertion von Brennecke, Nicholas, Cali, Ignazio, Mok, Tze How, Speedy, Helen, Genomics England Research Consortium, Hosszu, Laszlo L P, Stehmann, Christiane, Cracco, Laura, Puoti, Gianfranco, Prior, Thomas W, Cohen, Mark L, Collins, Steven J, Mead, Simon, Appleby, Brian S

Volltext

Ex vivo mammalian prions are formed of paired double helical prion protein fibrils von Terry, Cassandra, Wenborn, Adam, Gros, Nathalie, Sells, Jessica, Joiner, Susan, Hosszu, Laszlo L. P., Tattum, M. Howard, Panico, Silvia, Clare, Daniel K., Collinge, John, Saibil, Helen R., Wadsworth, Jonathan D. F.

Volltext

N-terminal Domain of Prion Protein Directs Its Oligomeric Association von Trevitt, Clare R., Hosszu, Laszlo L.P., Batchelor, Mark, Panico, Silvia, Terry, Cassandra, Nicoll, Andrew J., Risse, Emmanuel, Taylor, William A., Sandberg, Malin K., Al-Doujaily, Huda, Linehan, Jacqueline M., Saibil, Helen R., Scott, David J., Collinge, John, Waltho, Jonathan P., Clarke, Anthony R.

Volltext

High-affinity tamoxifen analogues retain extensive positional disorder when bound to calmodulin von Milanesi, Lilia, Trevitt, Clare R, Whitehead, Brian, Hounslow, Andrea M, Tomas, Salvador, Hosszu, Laszlo L P, Hunter, Christopher A, Waltho, Jonathan P

Volltext

Structural effects of the highly protective V127 polymorphism on human prion protein von Hosszu, Laszlo L. P., Conners, Rebecca, Sangar, Daljit, Batchelor, Mark, Sawyer, Elizabeth B., Fisher, Stuart, Cliff, Matthew J., Hounslow, Andrea M., McAuley, Katherine, Leo Brady, R., Jackson, Graham S., Bieschke, Jan, Waltho, Jonathan P., Collinge, John

Volltext

A systematic investigation of production of synthetic prions from recombinant prion protein von Schmidt, Christian, Fizet, Jeremie, Properzi, Francesca, Batchelor, Mark, Sandberg, Malin K., Edgeworth, Julie A., Afran, Louise, Ho, Sammy, Badhan, Anjna, Klier, Steffi, Linehan, Jacqueline M., Brandner, Sebastian, Hosszu, Laszlo L. P., Tattum, M. Howard, Jat, Parmjit, Clarke, Anthony R., Klöhn, Peter C., Wadsworth, Jonathan D. F., Jackson, Graham S., Collinge, John

Volltext

Definable Equilibrium States in the Folding of Human Prion Protein von Hosszu, Laszlo L. P, Wells, Mark A, Jackson, Graham S, Jones, Samantha, Batchelor, Mark, Clarke, Anthony R, Craven, C. Jeremy, Waltho, Jonathan P, Collinge, John

Volltext

Evaluating the causality of novel sequence variants in the prion protein gene by example von Mok, Tze How, Koriath, Carolin, Jaunmuktane, Zane, Campbell, Tracy, Joiner, Susan, Wadsworth, Jonathan D.F., Hosszu, Laszlo L.P., Brandner, Sebastian, Parvez, Ambereen, Truelsen, Thomas Clement, Lund, Eva Løbner, Saha, Romi, Collinge, John, Mead, Simon

Volltext

Conformational Properties of β-PrP von Hosszu, Laszlo L.P., Trevitt, Clare R., Jones, Samantha, Batchelor, Mark, Scott, David J., Jackson, Graham S., Collinge, John, Waltho, Jonathan P., Clarke, Anthony R.

Volltext

The H187R Mutation of the Human Prion Protein Induces Conversion of Recombinant Prion Protein to the PrPSc-like Form von Hosszu, Laszlo L. P, Tattum, M. Howard, Jones, Samantha, Trevitt, Clare R, Wells, Mark A, Waltho, Jonathan P, Collinge, John, Jackson, Graham S, Clarke, Anthony R

Volltext

Loss of Residues 119–136, Including the First β-strand of Human Prion Protein, Generates an Aggregation-competent Partially “Open” Form von Hosszu, Laszlo L.P., Sangar, Daljit, Batchelor, Mark, Risse, Emmanuel, Hounslow, Andrea M., Collinge, John, Waltho, Jonathan P., Bieschke, Jan

Volltext

Domain Behavior during the Folding of a Thermostable Phosphoglycerate Kinase von Parker, Martin J, Spencer, James, Jackson, Graham S, Burston, Steven G, Hosszu, Laszlo L. P, Craven, C. Jeremy, Waltho, Jonathan P, Clarke, Anthony R

Volltext

Structural mobility of the human prion protein probed by backbone hydrogen exchange von Clarke, Anthony R, Hosszu, Laszlo L. P, Baxter, Nicola J, Jackson, Graham S, Power, Aisling, Waltho, Jonathan P, Craven, C. Jeremy, Collinge, John

Volltext

Structure of a kinetic protein folding intermediate by equilibrium amide exchange von Hosszu, Laszlo L. P, Craven, C. Jeremy, Parker, Martin J, Lorch, Mark, Spencer, James, Clarke, Anthony R, Waltho, Jonathan P

Volltext

The Residue 129 Polymorphism in Human Prion Protein Does Not Confer Susceptibility to Creutzfeldt-Jakob Disease by Altering the Structure or Global Stability of PrPC von Hosszu, Laszlo L P, Jackson, Graham S, Trevitt, Clare R, Jones, Samantha, Batchelor, Mark, Bhelt, Daljit, Prodromidou, Kanella, Clarke, Anthony R, Waltho, Jonathan P, Collinge, John

Volltext

The H187R mutation of the human prion protein induces conversion of recombinant prion protein to the PrP(Sc)-like form von Hosszu, Laszlo L P, Tattum, M Howard, Jones, Samantha, Trevitt, Clare R, Wells, Mark A, Waltho, Jonathan P, Collinge, John, Jackson, Graham S, Clarke, Anthony R

Volltext