Structural Basis of Microtubule Stabilization by Discodermolide von Prota, Andrea E., Bargsten, Katja, Redondo‐Horcajo, Mariano, Smith, Amos B., Yang, Chia‐Ping H., McDaid, Hayley M., Paterson, Ian, Horwitz, Susan B., Fernando Díaz, José, Steinmetz, Michel O.

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Activation of the Steroid and Xenobiotic Receptor (Human Pregnane X Receptor) by Nontaxane Microtubule-Stabilizing Agents von Mani, Sridhar, Huang, Haiyan, Sundarababu, Sumathy, Liu, Wenjing, Kalpana, Ganjam, Smith, Amos B, Horwitz, Susan B

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Highly Concise Routes to Epothilones:  The Total Synthesis and Evaluation of Epothilone 490 von Biswas, Kaustav, Lin, Hong, Njardarson, Jon T, Chappell, Mark D, Chou, Ting-Chao, Guan, Yongbiao, Tong, William P, He, Lifeng, Horwitz, Susan B, Danishefsky, Samuel J

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The Effect of Ketoconazole on the Pharmacokinetics and Pharmacodynamics of Ixabepilone: A First in Class Epothilone B Analogue in Late-Phase Clinical Development von Goel, Sanjay, Cohen, Marvin, Cömezoglu, S Nilgün, Perrin, Lionel, André, François, Jayabalan, David, Iacono, Lisa, Comprelli, Adriana, Ly, Van T, Zhang, Donglu, Xu, Carrie, Humphreys, W Griffith, McDaid, Hayley, Goldberg, Gary, Horwitz, Susan B, Mani, Sridhar

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Remote Effects in Macrolide Formation through Ring-Forming Olefin Metathesis:  An Application to the Synthesis of Fully Active Epothilone Congeners von Meng, Dongfang, Su, Dai-Shi, Balog, Aaron, Bertinato, Peter, Sorensen, Erik J, Danishefsky, Samuel J, Zheng, Yu-Huang, Chou, Ting-Chao, He, Lifeng, Horwitz, Susan B

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Design, Synthesis, and Biological Evaluation of New-Generation Taxoids von Ojima, Iwao, Chen, Jin, Sun, Liang, Borella, Christopher P, Wang, Tao, Miller, Michael L, Lin, Songnian, Geng, Xudong, Kuznetsova, Larisa, Qu, Chuanxing, Gallager, David, Zhao, Xianrui, Zanardi, Ilaria, Xia, Shujun, Horwitz, Susan B, Mallen-St. Clair, Jon, Guerriero, Jennifer L, Bar-Sagi, Dafna, Veith, Jean M, Pera, Paula, Bernacki, Ralph J

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Synthesis and biological evaluation of novel 3′-difluorovinyl taxoids von Kuznetsova, Larissa, Sun, Liang, Chen, Jin, Zhao, Xianrui, Seitz, Joshua, Das, Manisha, Li, Yuan, Veith, Jean M., Pera, Paula, Bernacki, Ralph J., Xia, Shujun, Horwitz, Susan B., Ojima, Iwao

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Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells von KAVALLARIS, Maria, TAIT, A. Sasha, WALSH, Bradley J, LIFENG HE, HORWITZ, Susan B, NORRIS, Murray D, HABER, Michelle

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Design, Synthesis, and Biological Evaluation of Novel C14−C3′BzN-Linked Macrocyclic Taxoids von Sun, Liang, Geng, Xudong, Geney, Raphaël, Li, Yuan, Simmerling, Carlos, Li, Zhong, Lauher, Joseph W, Xia, Shujun, Horwitz, Susan B, Veith, Jean M, Pera, Paula, Bernacki, Ralph J, Ojima, Iwao

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Promotion of microtubule assembly in vitro by taxol von SCHIFF, PETER B, FANT, JANE, HORWITZ, SUSAN B

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Design, Synthesis, and Biological Evaluation of Novel C14-C3'BzN-Linked Macrocyclic Taxoids von LIANG SUN, XUDONG GENG, PERA, Paula, BEMACKI, Ralph J, OJIMA, Iwao, GENEY, Raphaël, YUAN LI, SIMMERLING, Carlos, ZHONG LI, LAUHER, Joseph W, SHUJUN XIA, HORWITZ, Susan B, VEITH, Jean M

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Biologically active taxol analogs with deleted A-ring side chain substituents and variable C-2' configurations von Swindell, Charles S, Krauss, Nancy E, Horwitz, Susan B, Ringel, Israel

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On the Total Synthesis and Preliminary Biological Evaluations of 15(R) and 15(S) Aza-dEpoB:  A Mitsunobu Inversion at C15 in Pre-Epothilone Fragments von Stachel, Shawn J, Chappell, Mark D, Lee, Chul Bom, Danishefsky, Samuel J, Chou, Ting-Chao, He, Lifeng, Horwitz, Susan B

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Abstract 664: Polymerization of human βIII-tubulin is distinct from βI-tubulin in a cell-free system von Yang, Chia-Ping H., Horwitz, Susan B.

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Properties and products of the degradation of DNA by bleomycin and iron(II) von Sausville, Edward A, Stein, Roland W, Peisach, Jack, Horwitz, Susan B

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Use of the Tubulin Bound Paclitaxel Conformation for Structure-Based Rational Drug Design von Geney, Raphaël, Sun, Liang, Pera, Paula, Bernacki, Ralph J., Xia, Shujun, Horwitz, Susan B., Simmerling, Carlos L., Ojima, Iwao

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Abstract 4687: The PI3K inhibitor GDC-0941 is synergistic with lapatinib, and mediates endocrine sensitivity in uterine papillary serous carcinoma von Levano, Kelly S., Rodriguez-Gabin, Alicia, Goldberg, Gary L., Horwitz, Susan B., Hou, June Y.

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Tumor Targeting by Covalent Conjugation of a Natural Fatty Acid to Paclitaxel von BRADLEY, Matthews O, WEBB, Nigel L, SWINDELL, Charles S, ANTHONY, Forrest H, DEVANESAN, Prabu, WITMAN, Philip A, HEMAMALINI, S, CHANDER, Madhavi C, BAKER, Sharyn D, LIFENG HE, HORWITZ, Susan Band

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Bleomycin-DNA interactions: fluorescence and proton magnetic resonance studies von Chien, Mingjien, Grollman, Arthur P, Horwitz, Susan B

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Effect of VP-16-213 on the intracellular degradation of DNA in HeLa cells von Loike, John D, Horwitz, Susan B

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