Akt-Mediated Phosphorylation of Argonaute 2 Downregulates Cleavage and Upregulates Translational Repression of MicroRNA Targets von Horman, Shane R., Janas, Maja M., Litterst, Claudia, Wang, Bingbing, MacRae, Ian J., Sever, Mary J., Morrissey, David V., Graves, Paul, Luo, Biao, Umesalma, Shaikamjad, Qi, Hank H., Miraglia, Loren J., Novina, Carl D., Orth, Anthony P.

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Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease von Yang, Jian-Ping, Toughiri, Rachel, Gounder, Anshu P, Scheibe, Dan, Petrus, Matt, Fink, Sarah J, Vallee, Sebastien, Kenniston, Jon, Papaioannou, Nikolaos, Langston, Steve, Gavva, Narender R, Horman, Shane R

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Microprotein-encoding RNA regulation in cells treated with pro-inflammatory and pro-fibrotic stimuli von Pai, Victor J, Lau, Calvin J, Garcia-Ruiz, Almudena, Donaldson, Cynthia, Vaughan, Joan M, Miller, Brendan, De Souza, Eduardo V, Pinto, Antonio M, Diedrich, Jolene, Gavva, Narender R, Yu, Shan, DeBoever, Christopher, Horman, Shane R, Saghatelian, Alan

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Growth Factor Independence 1 Antagonizes a p53-Induced DNA Damage Response Pathway in Lymphoblastic Leukemia von Khandanpour, Cyrus, Phelan, James D., Vassen, Lothar, Schütte, Judith, Chen, Riyan, Horman, Shane R., Gaudreau, Marie-Claude, Krongold, Joseph, Zhu, Jinfang, Paul, William E., Dührsen, Ulrich, Göttgens, Bertie, Grimes, H. Leighton, Möröy, Tarik

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Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets von Horman, Shane R, To, Jeremy, Lamb, John, Zoll, Jocelyn H, Leonetti, Nicole, Tu, Buu, Moran, Rita, Newlin, Robbin, Walker, John R, Orth, Anthony P

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An HTS-Compatible 3D Colony Formation Assay to Identify Tumor-Specific Chemotherapeutics von Horman, Shane R., To, Jeremy, Orth, Anthony P.

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Co-regulatory networks of human serum proteins link genetics to disease von Emilsson, Valur, Ilkov, Marjan, Lamb, John R, Finkel, Nancy, Gudmundsson, Elias F, Pitts, Rebecca, Hoover, Heather, Gudmundsdottir, Valborg, Horman, Shane R, Aspelund, Thor, Shu, Le, Trifonov, Vladimir, Sigurdsson, Sigurdur, Manolescu, Andrei, Zhu, Jun, Olafsson, Örn, Jakobsdottir, Johanna, Lesley, Scott A, To, Jeremy, Zhang, Jia, Harris, Tamara B, Launer, Lenore J, Zhang, Bin, Eiriksdottir, Gudny, Yang, Xia, Orth, Anthony P, Jennings, Lori L, Gudnason, Vilmundur

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Gfi1 integrates progenitor versus granulocytic transcriptional programming von Horman, Shane R., Velu, Chinavenmeni S., Chaubey, Aditya, Bourdeau, Tristan, Zhu, Jinfang, Paul, William E., Gebelein, Brian, Grimes, H. Leighton

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Retraction Note: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function von To, Jeremy, Quackenbush, Doug, Rowell, Emily, Li, Lilin, Reed, Connor, Lo, Frederick, Horman, Shane R.

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A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function (Retracted Article) von To, Jeremy, Quackenbush, Doug, Rowell, Emily, Li, Lilin, Reed, Connor, Lo, Frederick, Horman, Shane R.

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Integrating inflammatory biomarker analysis and artificial-intelligence-enabled image-based profiling to identify drug targets for intestinal fibrosis von Yu, Shan, Kalinin, Alexandr A., Paraskevopoulou, Maria D., Maruggi, Marco, Cheng, Jie, Tang, Jie, Icke, Ilknur, Luo, Yi, Wei, Qun, Scheibe, Dan, Hunter, Joel, Singh, Shantanu, Nguyen, Deborah, Carpenter, Anne E., Horman, Shane R.

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Genome-wide CRISPR Screening to Identify Drivers of TGF-β-Induced Liver Fibrosis in Human Hepatic Stellate Cells von Yu, Shan, Ericson, Matthew, Fanjul, Andrea, Erion, Derek M, Paraskevopoulou, Maria, Smith, Erin N, Cole, Banumathi, Feaver, Ryan, Holub, Corine, Gavva, Narender, Horman, Shane R, Huang, Jie

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High‐throughput CRISPR‐mediated 3D enrichment platform for functional interrogation of chemotherapeutic resistance von Grandhi, Taraka S. P., To, Jeremy, Romero, Angelica, Luna, Fabio, Barnes, Whitney, Walker, John, Moran, Rita, Newlin, Robbin, Miraglia, Loren, Orth, Anthony P., Horman, Shane R.

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Therapeutic antagonists of microRNAs deplete leukemia-initiating cell activity von Velu, Chinavenmeni S, Chaubey, Aditya, Phelan, James D, Horman, Shane R, Wunderlich, Mark, Guzman, Monica L, Jegga, Anil G, Zeleznik-Le, Nancy J, Chen, Jianjun, Mulloy, James C, Cancelas, Jose A, Jordan, Craig T, Aronow, Bruce J, Marcucci, Guido, Bhat, Balkrishen, Gebelein, Brian, Grimes, H Leighton

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Challenges and opportunities toward enabling phenotypic screening of complex and 3D cell models von Horman, Shane R, Hogan, Christopher, Delos Reyes, Karlo, Lo, Frederick, Antczak, Christophe

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RETRACTED ARTICLE: A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function von To, Jeremy, Quackenbush, Doug, Rowell, Emily, Li, Lilin, Reed, Connor, Lo, Frederick, Horman, Shane R.

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Gamma radiation increases endonuclease-dependent L1 retrotransposition in a cultured cell assay von Farkash, Evan A., Kao, Gary D., Horman, Shane R., Prak, Eline T. Luning

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Mutations in Growth Factor Independent-1 Associated with Human Neutropenia Block Murine Granulopoiesis through Colony Stimulating Factor-1 von Zarebski, Adrian, Velu, Chinavenmeni S., Baktula, Avinash M., Bourdeau, Tristan, Horman, Shane R., Basu, Sudeep, Bertolone, Salvatore J., Horwitz, Marshal, Hildeman, David A., Trent, John O., Grimes, H. Leighton

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A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function (Retraction of Vol 4, art no 56, 2021) von To, Jeremy, Quackenbush, Doug, Rowell, Emily, Li, Lilin, Reed, Connor, Lo, Frederick, Horman, Shane R.

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High-content analysis of three-dimensional tumor spheroids: investigating signaling pathways using small hairpin RNA von Horman, Shane R, To, Jeremy, Orth, Anthony P, Slawny, Nicky, Cuddihy, Meghan J, Caracino, Diana

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