IFI16 is an innate immune sensor for intracellular DNA von Bowie, Andrew G, Unterholzner, Leonie, Keating, Sinead E, Baran, Marcin, Horan, Kristy A, Jensen, Søren B, Sharma, Shruti, Sirois, Cherilyn M, Jin, Tengchuan, Latz, Eicke, Xiao, T Sam, Fitzgerald, Katherine A, Paludan, Søren R

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An ISO-certified genomics workflow for identification and surveillance of antimicrobial resistance von Sherry, Norelle L., Horan, Kristy A., Ballard, Susan A., Gonҫalves da Silva, Anders, Gorrie, Claire L., Schultz, Mark B., Stevens, Kerrie, Valcanis, Mary, Sait, Michelle L., Stinear, Timothy P., Howden, Benjamin P., Seemann, Torsten

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INPP5E regulates phosphoinositide-dependent cilia transition zone function von Dyson, Jennifer M, Conduit, Sarah E, Feeney, Sandra J, Hakim, Sandra, DiTommaso, Tia, Fulcher, Alex J, Sriratana, Absorn, Ramm, Georg, Horan, Kristy A, Gurung, Rajendra, Wicking, Carol, Smyth, Ian, Mitchell, Christina A

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The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease von Ooms, Lisa M, Horan, Kristy A, Rahman, Parvin, Seaton, Gillian, Gurung, Rajendra, Kethesparan, Dharini S, Mitchell, Christina A

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Proteasomal degradation of herpes simplex virus capsids in macrophages releases DNA to the cytosol for recognition by DNA sensors von Horan, Kristy A, Hansen, Kathrine, Jakobsen, Martin R, Holm, Christian K, Søby, Stine, Unterholzner, Leonie, Thompson, Mikayla, West, John A, Iversen, Marie B, Rasmussen, Simon B, Ellermann-Eriksen, Svend, Kurt-Jones, Evelyn, Landolfo, Santo, Damania, Blossom, Melchjorsen, Jesper, Bowie, Andrew G, Fitzgerald, Katherine A, Paludan, Søren R

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TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice von Reinert, Line S, Harder, Louis, Holm, Christian K, Iversen, Marie B, Horan, Kristy A, Dagnæs-Hansen, Frederik, Ulhøi, Benedicte P, Holm, Thomas H, Mogensen, Trine H, Owens, Trevor, Nyengaard, Jens R, Thomsen, Allan R, Paludan, Søren R

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Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA von Berg, Randi K, Melchjorsen, Jesper, Rintahaka, Johanna, Diget, Elisabeth, Søby, Stine, Horan, Kristy A, Gorelick, Robert J, Matikainen, Sampsa, Larsen, Carsten S, Ostergaard, Lars, Paludan, Søren R, Mogensen, Trine H

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Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection von Sun, Chenglong, Schattgen, Stefan A, Pisitkun, Prapaporn, Jorgensen, Joan P, Hilterbrand, Adam T, Wang, Lucas J, West, John A, Hansen, Kathrine, Horan, Kristy A, Jakobsen, Martin R, O'Hare, Peter, Adler, Heiko, Sun, Ren, Ploegh, Hidde L, Damania, Blossom, Upton, Jason W, Fitzgerald, Katherine A, Paludan, Søren R

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HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6 von Gonzalez-Dosal, Regina, Horan, Kristy A, Rahbek, Stine H, Ichijo, Hidenori, Chen, Zhijian J, Mieyal, John J, Hartmann, Rune, Paludan, Søren R

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Early Innate Recognition of Herpes Simplex Virus in Human Primary Macrophages Is Mediated via the MDA5/MAVS-Dependent and MDA5/MAVS/RNA Polymerase III-Independent Pathways von Melchjorsen, Jesper, Rintahaka, Johanna, Søby, Stine, Horan, Kristy A, Poltajainen, Alina, Østergaard, Lars, Paludan, Søren R, Matikainen, Sampsa

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Extracellular 2′-5′ Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity von KRISTIANSEN, Helle, SCHERER, Christina A, PALUDAN, Søren R, HARTMANN, Rune, MCVEAN, Maralee, IADONATO, Shawn P, VENDS, Susanne, THAVACHELVAM, Karthiga, STEFFENSEN, Thomas B, HORAN, Kristy A, KURI, Thomas, WEBER, Friedemann

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Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway von Hansen, Kathrine, Prabakaran, Thaneas, Laustsen, Anders, Jørgensen, Sofie E, Rahbæk, Stine H, Jensen, Søren B, Nielsen, Rikke, Leber, Jess H, Decker, Thomas, Horan, Kristy A, Jakobsen, Martin R, Paludan, Søren R

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Recognition of herpesviruses by the innate immune system von Paludan, Søren R, Bowie, Andrew G, Horan, Kristy A, Fitzgerald, Katherine A

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Prolonged Outbreak of Multidrug-Resistant Shigella sonnei Harboring blaCTX-M-27 in Victoria, Australia von Ingle, Danielle J., Andersson, Patiyan, Valcanis, Mary, Barnden, Jessica, da Silva, Anders Goncalves, Horan, Kristy A., Seemann, Torsten, Easton, Marion, Williamson, Deborah A., Sherry, Norelle L., Howden, Benjamin P.

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Assessing the subcellular distribution of oncogenic phosphoinositide 3-kinase using microinjection into live cells von Layton, Meredith J, Rynkiewicz, Natalie K, Ivetac, Ivan, Horan, Kristy A, Mitchell, Christina A, Phillips, Wayne A

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Activation of autophagy by α-herpesviruses in myeloid cells is mediated by cytoplasmic viral DNA through a mechanism dependent on stimulator of IFN genes von Rasmussen, Simon B, Horan, Kristy A, Holm, Christian K, Stranks, Amanda J, Mettenleiter, Thomas C, Simon, A Katharina, Jensen, Søren B, Rixon, Frazer J, He, Bin, Paludan, Søren R

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Prolonged Outbreak of Multidrug-Resistant Shigella sonnei Harboring bla CTX-M-27 in Victoria, Australia von Ingle, Danielle J., Andersson, Patiyan, Valcanis, Mary, Barnden, Jessica, da Silva, Anders Gonçalves, Horan, Kristy A., Seemann, Torsten, Easton, Marion, Williamson, Deborah A., Sherry, Norelle L., Howden, Benjamin P.

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Regulation of PI(3)K/Akt signalling and cellular transformation by inositol polyphosphate 4-phosphatase-1 von Ivetac, Ivan, Gurung, Rajendra, Hakim, Sandra, Horan, Kristy A, Sheffield, David A, Binge, Lauren C, Majerus, Philip W, Tiganis, Tony, Mitchell, Christina A

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Mitochondria-derived reactive oxygen species negatively regulates immune innate signaling pathways triggered by a DNA virus, but not by an RNA virus von Gonzalez-Dosal, Regina, Horan, Kristy A., Paludan, Søren R.

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Recognition of herpesviruses by the innate immune system von Paludan, Soren R, Bowie, Andrew G, Horan, Kristy A, Fitzgerald, Katherine A

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