Cell-free nucleic acids as biomarkers in cancer patients von Pantel, Klaus, Schwarzenbach, Heidi, Hoon, Dave S. B

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Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA von Lanman, Richard B, Mortimer, Stefanie A, Zill, Oliver A, Sebisanovic, Dragan, Lopez, Rene, Blau, Sibel, Collisson, Eric A, Divers, Stephen G, Hoon, Dave S B, Kopetz, E Scott, Lee, Jeeyun, Nikolinakos, Petros G, Baca, Arthur M, Kermani, Bahram G, Eltoukhy, Helmy, Talasaz, AmirAli

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Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy von Ma, Shijun, Zhao, Yue, Lee, Wee Chyan, Ong, Li-Teng, Lee, Puay Leng, Jiang, Zemin, Oguz, Gokce, Niu, Zhitong, Liu, Min, Goh, Jian Yuan, Wang, Wenyu, Bustos, Matias A., Ehmsen, Sidse, Ramasamy, Adaikalavan, Hoon, Dave S. B., Ditzel, Henrik J., Tan, Ern Yu, Chen, Qingfeng, Yu, Qiang

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Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation von Lee, Heehyoung, Zhang, Peng, Herrmann, Andreas, Yang, Chunmei, Xin, Hong, Wang, Zhenghe, Hoon, Dave S. B, Forman, Stephen J, Jove, Richard, Riggs, Arthur D, Yu, Hua

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LINE-1 hypomethylation during primary colon cancer progression von Sunami, Eiji, de Maat, Michiel, Vu, Anna, Turner, Roderick R, Hoon, Dave S B

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Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19 von Lee, Jihoon W., Su, Yapeng, Baloni, Priyanka, Chen, Daniel, Pavlovitch-Bedzyk, Ana Jimena, Yuan, Dan, Duvvuri, Venkata R., Ng, Rachel H., Choi, Jongchan, Xie, Jingyi, Zhang, Rongyu, Murray, Kim, Kornilov, Sergey, Smith, Brett, Magis, Andrew T., Hoon, Dave S. B., Hadlock, Jennifer J., Goldman, Jason D., Price, Nathan D., Gottardo, Raphael, Davis, Mark M., Hood, Leroy, Greenberg, Philip D., Heath, James R.

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Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma von Fukuda, Yasunari, Bustos, Matias A., Cho, Sung-Nam, Roszik, Jason, Ryu, Suyeon, Lopez, Victor M., Burks, Jared K., Lee, Jeffrey E., Grimm, Elizabeth A., Hoon, Dave S. B., Ekmekcioglu, Suhendan

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B7H3 regulates differentiation and serves as a potential biomarker and theranostic target for human glioblastoma von Zhang, Jingwen, Wang, Jinhua, Marzese, Diego M., Wang, Xiaowen, Yang, Zixiao, Li, Chunjie, Zhang, Haibo, Zhang, Jinsen, Chen, Clark C., Kelly, Daniel F., Hua, Wei, Hoon, Dave S.B., Mao, Ying

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Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer von Achinger-Kawecka, Joanna, Valdes-Mora, Fatima, Luu, Phuc-Loi, Giles, Katherine A., Caldon, C. Elizabeth, Qu, Wenjia, Nair, Shalima, Soto, Sebastian, Locke, Warwick J., Yeo-Teh, Nicole S., Gould, Cathryn M., Du, Qian, Smith, Grady C., Ramos, Irene R., Fernandez, Kristine F., Hoon, Dave S., Gee, Julia M. W., Stirzaker, Clare, Clark, Susan J.

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Cell-free plasma microRNAs that identify patients with glioblastoma von Bustos, Matias A., Rahimzadeh, Negin, Ryu, Suyeon, Gross, Rebecca, Tran, Linh T., Renteria-Lopez, Victor M., Ramos, Romela I., Eisenberg, Amy, Hothi, Parvinder, Kesari, Santosh, Barkhoudarian, Garni, Takasumi, Yuki, Cobbs, Charles, Kelly, Daniel F., Hoon, Dave S.B.

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B7-H4(B7x)-Mediated Cross-talk between Glioma-Initiating Cells and Macrophages via the IL6/JAK/STAT3 Pathway Lead to Poor Prognosis in Glioma Patients von Yao, Yu, Ye, Hongxing, Qi, Zengxin, Mo, Lianjie, Yue, Qi, Baral, Aparajita, Hoon, Dave S B, Vera, Juan Carlos, Heiss, John D, Chen, Clark C, Zhang, Jianmin, Jin, Kunlin, Wang, Ying, Zang, Xingxing, Mao, Ying, Zhou, Liangfu

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miR-29c plays a suppressive role in breast cancer by targeting the TIMP3/STAT1/FOXO1 pathway von Li, Wan, Yi, Jie, Zheng, Xiangjin, Liu, Shiwei, Fu, Weiqi, Ren, Liwen, Li, Li, Hoon, Dave S B, Wang, Jinhua, Du, Guanhua

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B7-H3 Ligand Expression by Primary Breast Cancer and Associated With Regional Nodal Metastasis von ARIGAMI, Takaaki, NARITA, Norihiko, MIZUNO, Ryuichi, NGUYEN, Linhda, XING YE, CHUNG, Alice, GIULIANO, Armando E, HOON, Dave S. B

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Liquid biopsy utility for the surveillance of cutaneous malignant melanoma patients von Huang, Sharon K., Hoon, Dave S.B.

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S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites von Deng, Jiehui, Liu, Yong, Lee, Heehyoung, Herrmann, Andreas, Zhang, Wang, Zhang, Chunyan, Shen, Shudan, Priceman, Saul J., Kujawski, Maciej, Pal, Sumanta K., Raubitschek, Andrew, Hoon, Dave S.B., Forman, Stephen, Figlin, Robert A., Liu, Jie, Jove, Richard, Yu, Hua

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Current status of gastrointestinal tract cancer brain metastasis and the use of blood-based cancer biomarker biopsy von Shoji, Yoshiaki, Furuhashi, Satoru, Kelly, Daniel F., Bilchik, Anton J., Hoon, Dave S. B., Bustos, Matias A.

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Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence von Goh, Jian Yuan, Feng, Min, Wang, Wenyu, Oguz, Gokce, Yatim, Siti Maryam J M, Lee, Puay Leng, Bao, Yi, Lim, Tse Hui, Wang, Panpan, Tam, Wai Leong, Kodahl, Annette R, Lyng, Maria B, Sarma, Suman, Lin, Selena Y, Lezhava, Alexander, Yap, Yoon Sim, Lim, Alvin S T, Hoon, Dave S B, Ditzel, Henrik J, Lee, Soo Chin, Tan, Ern Yu, Yu, Qiang

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Epigenetic Regulation of Cancer Stem Cell Genes in Triple-Negative Breast Cancer von Kagara, Naofumi, Huynh, Kelly T, Kuo, Christine, Okano, Hideyuki, Sim, Myung Shin, Elashoff, David, Chong, Kelly, Giuliano, Armando E, Hoon, Dave S.B

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Prediction of Breast Tumor Progression by Integrity of Free Circulating DNA in Serum von UMETANI, Naoyuki, GIULIANO, Armando E, HIRAMATSU, Suzanne H, AMERSI, Farin, NAKAGAWA, Taku, MARTINO, Silvana, HOON, Dave S. B

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B cells promote tumor progression via STAT3 regulated-angiogenesis von Yang, Chunmei, Lee, Heehyoung, Pal, Sumanta, Jove, Veronica, Deng, Jiehui, Zhang, Wang, Hoon, Dave S B, Wakabayashi, Mark, Forman, Stephen, Yu, Hua

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