Harnessing albumin as a carrier for cancer therapies von Hoogenboezem, Ella N., Duvall, Craig L.

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Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy von Hoogenboezem, Ella N., Patel, Shrusti S., Lo, Justin H., Cavnar, Ashley B., Babb, Lauren M., Francini, Nora, Gbur, Eva F., Patil, Prarthana, Colazo, Juan M., Michell, Danielle L., Sanchez, Violeta M., McCune, Joshua T., Ma, Jinqi, DeJulius, Carlisle R., Lee, Linus H., Rosch, Jonah C., Allen, Ryan M., Stokes, Larry D., Hill, Jordan L., Vickers, Kasey C., Cook, Rebecca S., Duvall, Craig L.

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Creation of an injectable in situ gelling native extracellular matrix for nucleus pulposus tissue engineering von Wachs, RA, Hoogenboezem, EN, Huda, HI, Xin, S, Porvasnik, SL, Schmidt, CE

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Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing von Patel, Shrusti S., Hoogenboezem, Ella N., Yu, Fang, DeJulius, Carlisle R., Fletcher, R. Brock, Sorets, Alex G., Cherry, Fiona K., Lo, Justin H., Bezold, Mariah G., Francini, Nora, d’Arcy, Richard, Brasuell, Jordan E., Cook, Rebecca S., Duvall, Craig L.

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Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes von Jackson, Meredith A., Bedingfield, Sean K., Yu, Fang, Stokan, Mitchell E., Miles, Rachel E., Curvino, Elizabeth J., Hoogenboezem, Ella N., Bonami, Rachel H., Patel, Shrusti S., Kendall, Peggy L., Giorgio, Todd D., Duvall, Craig L.

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Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers von Jackson, Meredith A., Patel, Shrusti S., Yu, Fang, Cottam, Matthew A., Glass, Evan B., Hoogenboezem, Ella N., Fletcher, R. Brock, Dollinger, Bryan R., Patil, Prarthana, Liu, Danielle D., Kelly, Isom B., Bedingfield, Sean K., King, Allyson R., Miles, Rachel E., Hasty, Alyssa M., Giorgio, Todd D., Duvall, Craig L.

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Albumin-Binding Aptamer Chimeras for Improved siRNA Bioavailability von Rosch, Jonah C., Hoogenboezem, Ella N., Sorets, Alexander G., Duvall, Craig L., Lippmann, Ethan S.

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Abstract 2706: Therapeutic silencing of Rictor using siRNA nanoparticles to selectively block mTORC2 signaling in triple negative breast cancer von Patel, Shrusti S., Hoogenboezem, Ella N., Yu, Fang, Sorets, Alex G., Cherry, Fiona K., Lo, Justin H., Francini, Nora, d'Arcy, Richard A., Cook, Rebecca S., Duvall, Craig L.

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