The emergent landscape of the mouse gut endoderm at single-cell resolution von Nowotschin, Sonja, Setty, Manu, Kuo, Ying-Yi, Liu, Vincent, Garg, Vidur, Sharma, Roshan, Simon, Claire S., Saiz, Nestor, Gardner, Rui, Boutet, Stéphane C., Church, Deanna M., Hoodless, Pamela A., Hadjantonakis, Anna-Katerina, Pe’er, Dana

Volltext

SOX9 reprograms endothelial cells by altering the chromatin landscape von Fuglerud, Bettina M, Drissler, Sibyl, Lotto, Jeremy, Stephan, Tabea L, Thakur, Avinash, Cullum, Rebecca, Hoodless, Pamela A

Volltext

Slug Is a Direct Notch Target Required for Initiation of Cardiac Cushion Cellularization von Niessen, Kyle, Fu, YangXin, Chang, Linda, Hoodless, Pamela A., McFadden, Deborah, Karsan, Aly

Volltext

Single-Cell Transcriptomics Reveals Early Emergence of Liver Parenchymal and Non-parenchymal Cell Lineages von Lotto, Jeremy, Drissler, Sibyl, Cullum, Rebecca, Wei, Wei, Setty, Manu, Bell, Erin M., Boutet, Stéphane C., Nowotschin, Sonja, Kuo, Ying-Yi, Garg, Vidur, Pe’er, Dana, Church, Deanna M., Hadjantonakis, Anna-Katerina, Hoodless, Pamela A.

Volltext

Notch Initiates the Endothelial-to-Mesenchymal Transition in the Atrioventricular Canal through Autocrine Activation of Soluble Guanylyl Cyclase von Chang, Alex C.Y., Fu, YangXin, Garside, Victoria C., Niessen, Kyle, Chang, Linda, Fuller, Megan, Setiadi, Audi, Smrz, Justin, Kyle, Alastair, Minchinton, Andrew, Marra, Marco, Hoodless, Pamela A., Karsan, Aly

Volltext

Cell diversity and plasticity during atrioventricular heart valve EMTs von Lotto, Jeremy, Cullum, Rebecca, Drissler, Sibyl, Arostegui, Martin, Garside, Victoria C., Fuglerud, Bettina M., Clement-Ranney, Makenna, Thakur, Avinash, Underhill, T. Michael, Hoodless, Pamela A.

Volltext

The role of the innate immune response regulatory gene ABCF1 in mammalian embryogenesis and development von Wilcox, Sara M, Arora, Hitesh, Munro, Lonna, Xin, Jian, Fenninger, Franz, Johnson, Laura A, Pfeifer, Cheryl G, Choi, Kyung Bok, Hou, Juan, Hoodless, Pamela A, Jefferies, Wilfred A

Volltext

Hippo signaling influences HNF4A and FOXA2 enhancer switching during hepatocyte differentiation von Alder, Olivia, Cullum, Rebecca, Lee, Sam, Kan, Arohumam C, Wei, Wei, Yi, Yuyin, Garside, Victoria C, Bilenky, Misha, Griffith, Malachi, Morrissy, A Sorana, Robertson, Gordon A, Thiessen, Nina, Zhao, Yongjun, Chen, Qian, Pan, Duojia, Jones, Steven J M, Marra, Marco A, Hoodless, Pamela A

Volltext

Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives von Freyer, Laina, Hsu, Chih-Wei, Nowotschin, Sonja, Pauli, Andrea, Ishida, Junji, Kuba, Keiji, Fukamizu, Akiyoshi, Schier, Alexander F., Hoodless, Pamela A., Dickinson, Mary E., Hadjantonakis, Anna-Katerina

Volltext

Coxsackievirus-induced miR-21 disrupts cardiomyocyte interactions via the downregulation of intercalated disk components von Ye, Xin, Zhang, Huifang Mary, Qiu, Ye, Hanson, Paul J, Hemida, Maged Gomaa, Wei, Wei, Hoodless, Pamela A, Chu, Fanny, Yang, Decheng

Volltext

Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma von Takata, Katsuyoshi, Chong, Lauren C, Ennishi, Daisuke, Aoki, Tomohiro, Li, Michael Yu, Thakur, Avinash, Healy, Shannon, Viganò, Elena, Dao, Tao, Kwon, Daniel, Duns, Gerben, Nielsen, Julie S, Ben-Neriah, Susana, Tse, Ethan, Hung, Stacy S, Boyle, Merrill, Mun, Sung Soo, Bourne, Christopher M, Woolcock, Bruce, Telenius, Adèle, Kishida, Makoto, Rai, Shinya, Zhang, Allen W, Bashashati, Ali, Saberi, Saeed, D'Antonio, Gianluca, Nelson, Brad H, Shah, Sohrab P, Hoodless, Pamela A, Melnick, Ari M, Gascoyne, Randy D, Connors, Joseph M, Scheinberg, David A, Béguelin, Wendy, Scott, David W, Steidl, Christian

Volltext

SOX9 modulates the expression of key transcription factors required for heart valve development von Garside, Victoria C, Cullum, Rebecca, Alder, Olivia, Lu, Daphne Y, Vander Werff, Ryan, Bilenky, Mikhail, Zhao, Yongjun, Jones, Steven J M, Marra, Marco A, Underhill, T Michael, Hoodless, Pamela A

Volltext

Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties von Bowie, Michelle B, Kent, David G, Dykstra, Brad, McKnight, Kristen D, McCaffrey, Lindsay, Hoodless, Pamela A, Eaves, Connie J

Volltext

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding von Robertson, A Gordon, Bilenky, Mikhail, Tam, Angela, Zhao, Yongjun, Zeng, Thomas, Thiessen, Nina, Cezard, Timothee, Fejes, Anthony P, Wederell, Elizabeth D, Cullum, Rebecca, Euskirchen, Ghia, Krzywinski, Martin, Birol, Inanc, Snyder, Michael, Hoodless, Pamela A, Hirst, Martin, Marra, Marco A, Jones, Steven J M

Volltext

Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling von Coulombe, Patrick, Paliouras, Grigorios N., Clayton, Ashley, Hussainkhel, Angela, Fuller, Megan, Jovanovic, Vida, Dauphinee, Shauna, Umlandt, Patricia, Xiang, Ping, Kyle, Alistair H., Minchinton, Andrew I., Humphries, R. Keith, Hoodless, Pamela A., Parker, Jeremy D.K., Wright, Joanne L., Karsan, Aly

Volltext

Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing von Wederell, Elizabeth D, Bilenky, Mikhail, Cullum, Rebecca, Thiessen, Nina, Dagpinar, Melis, Delaney, Allen, Varhol, Richard, Zhao, YongJun, Zeng, Thomas, Bernier, Bridget, Ingham, Matthew, Hirst, Martin, Robertson, Gordon, Marra, Marco A, Jones, Steven, Hoodless, Pamela A

Volltext

Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver von Hoffman, Brad G, Robertson, Gordon, Zavaglia, Bogard, Beach, Mike, Cullum, Rebecca, Lee, Sam, Soukhatcheva, Galina, Li, Leping, Wederell, Elizabeth D, Thiessen, Nina, Bilenky, Mikhail, Cezard, Timothee, Tam, Angela, Kamoh, Baljit, Birol, Inanc, Dai, Derek, Zhao, Yongjun, Hirst, Martin, Verchere, C Bruce, Helgason, Cheryl D, Marra, Marco A, Jones, Steven J M, Hoodless, Pamela A

Volltext

G protein-coupled estrogen receptor stimulates human trophoblast cell invasion via YAP-mediated ANGPTL4 expression von Cheng, Jung-Chien, Fang, Lanlan, Li, Yuxi, Thakur, Avinash, Hoodless, Pamela A., Guo, Yanjie, Wang, Zhen, Wu, Ze, Yan, Yang, Jia, Qiongqiong, Gao, Yibo, Han, Xiaoyu, Yu, Yiping, Sun, Ying-Pu

Volltext

HNF4A guides the MLL4 complex to establish and maintain H3K4me1 at gene regulatory elements von Thakur, Avinash, Park, Kwangjin, Cullum, Rebecca, Fuglerud, Bettina M., Khoshnoodi, Mina, Drissler, Sibyl, Stephan, Tabea L., Lotto, Jeremy, Kim, Donghwan, Gonzalez, Frank J., Hoodless, Pamela A.

Volltext

Fetal liver development and implications for liver disease pathogenesis von Lotto, Jeremy, Stephan, Tabea L., Hoodless, Pamela A.

Volltext