The spectrum of cardiovascular disease in the Marfan syndrome: A clinico-morphologic study of 18 necropsy patients and comparison to 151 previously reported necropsy patients von Roberts, William C, Honig, Howard S

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Severe aortic regurgitation secondary to idiopathic aortitis von Honig, Howard S., Weintraub, Alan M., Gomes, Mario N., Hufnagel, Charles A., Roberts, William C.

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Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials von Ostrowitzki, Susanne, Bittner, Tobias, Sink, Kaycee M, Mackey, Howard, Rabe, Christina, Honig, Lawrence S, Cassetta, Emanuele, Woodward, Michael, Boada, Mercè, van Dyck, Christopher H, Grimmer, Timo, Selkoe, Dennis J, Schneider, Andres, Blondeau, Kathleen, Hu, Nan, Quartino, Angelica, Clayton, David, Dolton, Michael, Dang, Yifan, Ostaszewski, Beth, Sanabria-Bohórquez, Sandra M, Rabbia, Michael, Toth, Balazs, Eichenlaub, Udo, Smith, Jillian, Honigberg, Lee A, Doody, Rachelle S

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Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease von Vogel, Jacob W., Iturria-Medina, Yasser, Strandberg, Olof T., Smith, Ruben, Levitis, Elizabeth, Evans, Alan C., Hansson, Oskar

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A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Pos... von Galasko, Douglas, Farlow, Martin R, Lucey, Brendan P, Honig, Lawrence S, Elbert, Donald, Bateman, Randall, Momper, Jeremiah, Thomas, Ronald G, Rissman, Robert A, Pa, Judy, Aslanyan, Vahan, Balasubramanian, Archana, West, Tim, Maccecchini, Maria, Feldman, Howard H

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Four distinct trajectories of tau deposition identified in Alzheimer’s disease von Vogel, Jacob W., Young, Alexandra L., Oxtoby, Neil P., Smith, Ruben, Ossenkoppele, Rik, Strandberg, Olof T., La Joie, Renaud, Aksman, Leon M., Grothe, Michel J., Iturria-Medina, Yasser, Pontecorvo, Michael J., Devous, Michael D., Rabinovici, Gil D., Alexander, Daniel C., Lyoo, Chul Hyoung, Evans, Alan C., Hansson, Oskar

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Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer’s Disease using structural MR and FDG-PET images von Lu, Donghuan, Popuri, Karteek, Ding, Gavin Weiguang, Balachandar, Rakesh, Beg, Mirza Faisal

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Fatty Acid Composition of Proximal Femur Bone Marrow Adipose Tissue in Subjects With Systemic Lupus Erythematous Using 3 T Magnetic Resonance Spectroscopy von Martel, Dimitri, Saxena, Amit, Belmont, Howard Michael, Honig, Stephen, Chang, Gregory

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Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis von Iturria-Medina, Y., Sotero, R. C., Toussaint, P. J., Mateos-Pérez, J. M., Evans, A. C.

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Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease von Franzmeier, Nicolai, Neitzel, Julia, Rubinski, Anna, Smith, Ruben, Strandberg, Olof, Ossenkoppele, Rik, Hansson, Oskar, Ewers, Michael

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Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease von Gonneaud, Julie, Baria, Alex T., Pichet Binette, Alexa, Gordon, Brian A., Chhatwal, Jasmeer P., Cruchaga, Carlos, Jucker, Mathias, Levin, Johannes, Salloway, Stephen, Farlow, Martin, Gauthier, Serge, Benzinger, Tammie L. S., Morris, John C., Bateman, Randall J., Breitner, John C. S., Poirier, Judes, Vachon-Presseau, Etienne, Villeneuve, Sylvia

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A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies von Nalls, Michael A, Duran, Raquel, Lopez, Grisel, Kurzawa-Akanbi, Marzena, McKeith, Ian G, Chinnery, Patrick F, Morris, Christopher M, Theuns, Jessie, Crosiers, David, Cras, Patrick, Engelborghs, Sebastiaan, De Deyn, Peter Paul, Van Broeckhoven, Christine, Mann, David M. A, Snowden, Julie, Pickering-Brown, Stuart, Halliwell, Nicola, Davidson, Yvonne, Gibbons, Linda, Harris, Jenny, Sheerin, Una-Marie, Bras, Jose, Hardy, John, Clark, Lorraine, Marder, Karen, Honig, Lawrence S, Berg, Daniela, Maetzler, Walter, Brockmann, Kathrin, Gasser, Thomas, Novellino, Fabiana, Quattrone, Aldo, Annesi, Grazia, De Marco, Elvira Valeria, Rogaeva, Ekaterina, Masellis, Mario, Black, Sandra E, Bilbao, Juan M, Foroud, Tatiana, Ghetti, Bernardino, Nichols, William C, Pankratz, Nathan, Halliday, Glenda, Lesage, Suzanne, Klebe, Stephan, Durr, Alexandra, Duyckaerts, Charles, Brice, Alexis, Giasson, Benoit I, Trojanowski, John Q, Hurtig, Howard I, Tayebi, Nahid, Landazabal, Claudia, Knight, Melanie A, Keller, Margaux, Singleton, Andrew B, Wolfsberg, Tyra G, Sidransky, Ellen

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Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers von VandeBunte, Anna M., Lee, Hyunwoo, Paolillo, Emily W., Hsiung, Ging‐Yuek Robin, Staffaroni, Adam M., Saloner, Rowan, Tartaglia, Carmela, Yaffe, Kristine, Knopman, David S., Ramos, Eliana Marisa, Rascovsky, Katya, Bozoki, Andrea C., Wong, Bonnie, Domoto‐Reilly, Kimiko, Snyder, Allison, Pressman, Peter, Mendez, Mario F., Litvan, Irene, Fields, Julie A., Galasko, Douglas R., Darby, Ryan, Masdeu, Joseph C., Pasqual, Maria Belen, Honig, Lawrence S., Ghoshal, Nupur, Appleby, Brian S., Mackenzie, Ian R., Heuer, Hilary W., Kramer, Joel H., Boxer, Adam L., Forsberg, Leah K., Boeve, Brad, Rosen, Howard J., Casaletto, Kaitlin B.

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Cerebrospinal fluid amyloid levels are associated with delayed memory retention in cognitively normal biomarker-negative older adults von Yeung, Lok-Kin, Hale, Christiane, Last, Briana S., Andrews, Howard, Sloan, Richard P., Honig, Lawrence S., Small, Scott A., Brickman, Adam M.

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Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology von Schmitz, Taylor W., Nathan Spreng, R.

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Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease von Pichet Binette, Alexa, Franzmeier, Nicolai, Spotorno, Nicola, Ewers, Michael, Brendel, Matthias, Biel, Davina, Strandberg, Olof, Janelidze, Shorena, Palmqvist, Sebastian, Mattsson-Carlgren, Niklas, Smith, Ruben, Stomrud, Erik, Ossenkoppele, Rik, Hansson, Oskar

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Ferritin levels in the cerebrospinal fluid predict Alzheimer’s disease outcomes and are regulated by APOE von Ayton, Scott, Faux, Noel G., Bush, Ashley I.

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The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory von Franzmeier, Nicolai, Rubinski, Anna, Neitzel, Julia, Ewers, Michael

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Type 2 diabetes mellitus, brain atrophy, and cognitive decline von Moran, Chris, Beare, Richard, Wang, Wei, Callisaya, Michele, Srikanth, Velandai, Weiner, Michael, Aisen, Paul, Petersen, Ronald, Jack, Clifford R., Jagust, William, Trojanowki, John Q., Toga, Arthur W., Beckett, Laurel, Green, Robert C., Saykin, Andrew J., Morris, John, Liu, Enchi, Montine, Tom, Gamst, Anthony, Thomas, Ronald G., Donohue, Michael, Walter, Sarah, Gessert, Devon, Sather, Tamie, Harvey, Danielle, Kornak, John, Dale, Anders, Bernstein, Matthew, Felmlee, Joel, Fox, Nick, Thompson, Paul, Schuff, Norbert, Alexander, Gene, DeCarli, Charles, Bandy, Dan, Koeppe, Robert A., Foster, Norm, Reiman, Eric M., Chen, Kewei, Mathis, Chet, Cairns, Nigel J., Taylor-Reinwald, Lisa, Trojanowki, J.Q., Shaw, Les, Lee, Virginia M.Y., Korecka, Magdalena, Crawford, Karen, Neu, Scott, Foroud, Tatiana M., Potkin, Steven, Shen, Li, Kachaturian, Zaven, Frank, Richard, Snyder, Peter J., Molchan, Susan, Kaye, Jeffrey, Quinn, Joseph, Lind, Betty, Dolen, Sara, Schneider, Lon S., Pawluczyk, Sonia, Spann, Bryan M., Brewer, James, Vanderswag, Helen, Heidebrink, Judith L., Lord, Joanne L., Johnson, Kris, Doody, Rachelle S., Villanueva-Meyer, Javier, Chowdhury, Munir, Stern, Yaakov, Honig, Lawrence S., Bell, Karen L., Morris, John C., Ances, Beau, Carroll, Maria, Leon, Sue, Mintun, Mark A., Schneider, Stacy, Marson, Daniel, Griffith, Randall, Clark, David, Grossman, Hillel, Mitsis, Effie, Romirowsky, Aliza, deToledo-Morrell, Leyla, Shah, Raj C., Duara, Ranjan, Varon, Daniel, Roberts, Peggy, Albert, Marilyn, Onyike, Chiadi, Kielb, Stephanie, Rusinek, Henry, de Leon, Mony J, Glodzik, Lidia, De Santi, Susan, Doraiswamy, P. Murali, Petrella, Jeffrey R., Coleman, R. Edward

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Non-coding variability at the APOE locus contributes to the Alzheimer’s risk von Zhou, Xiaopu, Chen, Yu, Mok, Kin Y., Kwok, Timothy C. Y., Mok, Vincent C. T., Guo, Qihao, Ip, Fanny C., Chen, Yuewen, Mullapudi, Nandita, Giusti-Rodríguez, Paola, Sullivan, Patrick F., Hardy, John, Fu, Amy K. Y., Li, Yun, Ip, Nancy Y.

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