Preclinical Antitumor Activity of a Novel Anti-c-KIT Antibody-Drug Conjugate against Mutant and Wild-type c-KIT-Positive Solid Tumors von Abrams, Tinya, Connor, Anu, Fanton, Christie, Cohen, Steven B, Huber, Thomas, Miller, Kathy, Hong, E Erica, Niu, Xiaohong, Kline, Janine, Ison-Dugenny, Marjorie, Harris, Sarah, Walker, Dana, Krauser, Klaus, Galimi, Francesco, Wang, Zhen, Ghoddusi, Majid, Mansfield, Keith, Lee-Hoeflich, Si Tuen, Holash, Jocelyn, Pryer, Nancy, Kluwe, William, Ettenberg, Seth A, Sellers, William R, Lees, Emma, Kwon, Paul, Abraham, Judith A, Schleyer, Siew C

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Design of Coltuximab Ravtansine, a CD19-Targeting Antibody–Drug Conjugate (ADC) for the Treatment of B‑Cell Malignancies: Structure–Activity Relationships and Preclinical Evaluatio... von Hong, E. Erica, Erickson, Hans, Lutz, Robert J, Whiteman, Kathleen R, Jones, Gregory, Kovtun, Yelena, Blanc, Veronique, Lambert, John M

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A New Triglycyl Peptide Linker for Antibody-Drug Conjugates (ADCs) with Improved Targeted Killing of Cancer Cells von Singh, Rajeeva, Setiady, Yulius Y, Ponte, Jose, Kovtun, Yelena V, Lai, Katharine C, Hong, E Erica, Fishkin, Nathan, Dong, Ling, Jones, Gregory E, Coccia, Jennifer A, Lanieri, Leanne, Veale, Karen, Costoplus, Juliet A, Skaletskaya, Anna, Gabriel, Rabih, Salomon, Paulin, Wu, Rui, Qiu, Qifeng, Erickson, Hans K, Lambert, John M, Chari, Ravi V J, Widdison, Wayne C

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Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing von Widdison, Wayne C, Ponte, Jose F, Coccia, Jennifer A, Lanieri, Leanne, Setiady, Yulius, Dong, Ling, Skaletskaya, Anna, Hong, E. Erica, Wu, Rui, Qiu, Qifeng, Singh, Rajeeva, Salomon, Paulin, Fishkin, Nathan, Harris, Luke, Maloney, Erin K, Kovtun, Yelena, Veale, Karen, Wilhelm, Sharon D, Audette, Charlene A, Costoplus, Juliet A, Chari, Ravi V. J

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Linker Design for Antibody–Drug Conjugates von Hong, E. Erica, Chari, Ravi

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Abstract 1695: Development of a novel antibody-drug conjugate for the treatment of c-Kit expressing solid tumors and AML von Abrams, Tinya J., Niu, Xiaohong, Embry, Millicent, Kline, Janine, Patawaran, Montesa, Fanton, Christie, Ison-Dugenny, Marjorie, Schneider, Tracy, Miller, Kathy, Wang, Zhen, Ghoddusi, Majid, Cohen, Steven, Hong, E. Erica, Lees, Emma, Schleyer, Siew

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Single duplex DNA sequencing with CODEC detects mutations with high sensitivity von Bae, Jin H., Liu, Ruolin, Roberts, Eugenia, Nguyen, Erica, Tabrizi, Shervin, Rhoades, Justin, Blewett, Timothy, Xiong, Kan, Gydush, Gregory, Shea, Douglas, An, Zhenyi, Patel, Sahil, Cheng, Ju, Sridhar, Sainetra, Liu, Mei Hong, Lassen, Emilie, Skytte, Anne-Bine, Grońska-Pęski, Marta, Shoag, Jonathan E., Evrony, Gilad D., Parsons, Heather A., Mayer, Erica L., Makrigiorgos, G. Mike, Golub, Todd R., Adalsteinsson, Viktor A.

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Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker von Blake, Georgina E. T., Zhao, Xiaohui, Yung, Hong wa, Burton, Graham J., Ferguson-Smith, Anne C., Hamilton, Russell S., Watson, Erica D.

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Zebrafish knockout of Down syndrome gene, DYRK1A , shows social impairments relevant to autism von Kim, Oc-Hee, Cho, Hyun-Ju, Han, Enna, Hong, Ted Inpyo, Ariyasiri, Krishan, Choi, Jung-Hwa, Hwang, Kyu-Seok, Jeong, Yun-Mi, Yang, Se-Yeol, Yu, Kweon, Park, Doo-Sang, Oh, Hyun-Woo, Davis, Erica E, Schwartz, Charles E, Lee, Jeong-Soo, Kim, Hyung-Goo, Kim, Cheol-Hee

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Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction von Gaskill, Christa F, Carrier, Erica J, Kropski, Jonathan A, Bloodworth, Nathaniel C, Menon, Swapna, Foronjy, Robert F, Taketo, M Mark, Hong, Charles C, Austin, Eric D, West, James D, Means, Anna L, Loyd, James E, Merryman, W David, Hemnes, Anna R, De Langhe, Stijn, Blackwell, Timothy S, Klemm, Dwight J, Majka, Susan M

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The Impact of Specialty Palliative Care in Pediatric Oncology: A Systematic Review von Kaye, Erica C., Weaver, Meaghann S., DeWitt, Leila Hamzi, Byers, Elizabeth, Stevens, Sarah E., Lukowski, Joe, Shih, Brandon, Zalud, Kristina, Applegarth, Jacob, Wong, Hong-Nei, Baker, Justin N., Ullrich, Christina K.

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Promoter Methylation Regulates Estrogen Receptor 2 in Human Endometrium and Endometriosis von Xue, Qing, Lin, Zhihong, Cheng, You-Hong, Huang, Chiang-Ching, Marsh, Erica, Yin, Ping, Milad, Magdy P, Confino, Edmond, Reierstad, Scott, Innes, Joy, Bulun, Serdar E

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Endoplasmic reticulum stress disrupts placental morphogenesis: implications for human intrauterine growth restriction von Yung, Hong wa, Hemberger, Myriam, Watson, Erica D, Senner, Claire E, Jones, Carolyn P, Kaufman, Randal J, Charnock-Jones, D Stephen, Burton, Graham J

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Oligogenic Effects of 16p11.2 Copy-Number Variation on Craniofacial Development von Qiu, Yuqi, Arbogast, Thomas, Lorenzo, Sandra Martin, Li, Hongying, Tang, Shih C., Richardson, Ellen, Hong, Oanh, Cho, Shawn, Shanta, Omar, Pang, Timothy, Corsello, Christina, Deutsch, Curtis K., Chevalier, Claire, Davis, Erica E., Iakoucheva, Lilia M., Herault, Yann, Katsanis, Nicholas, Messer, Karen, Sebat, Jonathan

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Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity von Dalton, Rachel, Lee, Seung‐been, Claw, Katrina G., Prasad, Bhagwat, Phillips, Brian R., Shen, Danny D., Wong, Lai Hong, Fade, Mitch, McDonald, Matthew G., Dunham, Maitreya J., Fowler, Douglas M., Rettie, Allan E., Schuetz, Erin, Thornton, Timothy A., Nickerson, Deborah A., Gaedigk, Andrea, Thummel, Kenneth E., Woodahl, Erica L.

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ClinGen — The Clinical Genome Resource von Rehm, Heidi L, Berg, Jonathan S, Brooks, Lisa D, Bustamante, Carlos D, Evans, James P, Landrum, Melissa J, Ledbetter, David H, Maglott, Donna R, Martin, Christa Lese, Nussbaum, Robert L, Plon, Sharon E, Ramos, Erin M, Sherry, Stephen T, Watson, Michael S

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Opportunities for Palliative Care in Patients With Burn Injury—A Systematic Review von Cook, Allyson C., Langston, Jessica A., Jaramillo, Joshua D., Edwards, Kristin E., Wong, Hong-nei, Aslakson, Rebecca A., Aslakson, Rebecca, Ast, Katherine, Carroll, Thomas, Dzeng, Elizabeth, Frechman, Erica, Goett, Rebecca, Harrison, Krista L., Kaye, Erica C., Kotwal, Ashwin, LeBlanc, Thomas W., Lo, Shelly S., Nageswaran, Savithri, Powell, Victoria, Powers, James, Rotella, Joseph, Ullrich, Christina, Vickey, Theresa, Wong, Susan

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cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor von Fujita, M, Richards, E M, Niciu, M J, Ionescu, D F, Zoghbi, S S, Hong, J, Telu, S, Hines, C S, Pike, V W, Zarate, C A, Innis, R B

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Protective mAbs and Cross-Reactive mAbs Raised by Immunization with Engineered Marburg Virus GPs von Fusco, Marnie L, Hashiguchi, Takao, Cassan, Robyn, Biggins, Julia E, Murin, Charles D, Warfield, Kelly L, Li, Sheng, Holtsberg, Frederick W, Shulenin, Sergey, Vu, Hong, Olinger, Gene G, Kim, Do H, Whaley, Kevin J, Zeitlin, Larry, Ward, Andrew B, Nykiforuk, Cory, Aman, M Javad, Berry, Jody D, Berry, Jody, Saphire, Erica Ollmann

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Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression von Davis, Eric S, Ghosh, Arunava, Coakley, Raymond D, Wrennall, Joe A, Lubamba, Bob A, Rowell, Temperance R, Dang, Hong, Pawlak, Erica A, Li, Quefeng, Alexis, Neil E, Ribeiro, Carla M P, Tarran, Robert

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