In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization von Michel, Maurice, Homan, Evert J., Wiita, Elisée, Pedersen, Kia, Almlöf, Ingrid, Gustavsson, Anna-Lena, Lundbäck, Thomas, Helleday, Thomas, Warpman Berglund, Ulrika

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Computational and Experimental Druggability Assessment of Human DNA Glycosylases von Michel, Maurice, Visnes, Torkild, Homan, Evert J, Seashore-Ludlow, Brinton, Hedenström, Mattias, Wiita, Elisée, Vallin, Karl, Paulin, Cynthia B. J, Zhang, Jiaxi, Wallner, Olov, Scobie, Martin, Schmidt, Andreas, Jenmalm-Jensen, Annika, Warpman Berglund, Ulrika, Helleday, Thomas

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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation von Visnes, Torkild, Cázares-Körner, Armando, Hao, Wenjing, Wallner, Olov, Masuyer, Geoffrey, Loseva, Olga, Mortusewicz, Oliver, Wiita, Elisée, Sarno, Antonio, Manoilov, Aleksandr, Astorga-Wells, Juan, Jemth, Ann-Sofie, Pan, Lang, Sanjiv, Kumar, Karsten, Stella, Gokturk, Camilla, Grube, Maurice, Homan, Evert J, Hanna, Bishoy M F, Paulin, Cynthia B J, Pham, Therese, Rasti, Azita, Berglund, Ulrika Warpman, von Nicolai, Catharina, Benitez-Buelga, Carlos, Koolmeister, Tobias, Ivanic, Dag, Iliev, Petar, Scobie, Martin, Krokan, Hans E, Baranczewski, Pawel, Artursson, Per, Altun, Mikael, Jensen, Annika Jenmalm, Kalderén, Christina, Ba, Xueqing, Zubarev, Roman A, Stenmark, Pål, Boldogh, Istvan, Helleday, Thomas

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GPCR Function in Autophagy Control: A Systematic Approach of Chemical Intervention von Sanz-Martinez, Pablo, Tascher, Georg, Cano-Franco, Sara, Cabrerizo-Poveda, Paloma, Münch, Christian, Homan, Evert J., Stolz, Alexandra

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PSW-Designer: An Open-Source Computational Platform for the Design and Virtual Screening of Photopharmacological Ligands von Simon, Icaro A., Homan, Evert J., Wijtmans, Maikel, Sundström, Michael, Leurs, Rob, De Esch, Iwan J. P., Zarzycka, Barbara A.

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Targeting OGG1 arrests cancer cell proliferation by inducing replication stress von Visnes, Torkild, Benítez-Buelga, Carlos, Cázares-Körner, Armando, Sanjiv, Kumar, Hanna, Bishoy M F, Mortusewicz, Oliver, Rajagopal, Varshni, Albers, Julian J, Hagey, Daniel W, Bekkhus, Tove, Eshtad, Saeed, Baquero, Juan Miguel, Masuyer, Geoffrey, Wallner, Olov, Müller, Sarah, Pham, Therese, Göktürk, Camilla, Rasti, Azita, Suman, Sharda, Torres-Ruiz, Raúl, Sarno, Antonio, Wiita, Elisée, Homan, Evert J, Karsten, Stella, Marimuthu, Karthick, Michel, Maurice, Koolmeister, Tobias, Scobie, Martin, Loseva, Olga, Almlöf, Ingrid, Unterlass, Judith Edda, Pettke, Aleksandra, Boström, Johan, Pandey, Monica, Gad, Helge, Herr, Patrick, Jemth, Ann-Sofie, El Andaloussi, Samir, Kalderén, Christina, Rodriguez-Perales, Sandra, Benítez, Javier, Krokan, Hans E, Altun, Mikael, Stenmark, Pål, Berglund, Ulrika Warpman, Helleday, Thomas

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The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform‐Selective Inhibitors von Scaletti, Emma R., Gustafsson Westergren, Robert, Andersson, Yasmin, Wiita, Elisee, Henriksson, Martin, Homan, Evert J., Jemth, Ann‐Sofie, Helleday, Thomas, Stenmark, Pål

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NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir von Zhang, Si Min, Rehling, Daniel, Jemth, Ann-Sofie, Throup, Adam, Landázuri, Natalia, Almlöf, Ingrid, Göttmann, Mona, Valerie, Nicholas C.K., Borhade, Sanjay R., Wakchaure, Prasad, Page, Brent D.G., Desroses, Matthieu, Homan, Evert J., Scobie, Martin, Rudd, Sean G., Berglund, Ulrika Warpman, Söderberg-Nauclér, Cecilia, Stenmark, Pål, Helleday, Thomas

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Development of a chemical probe against NUDT15 von Zhang, Si Min, Desroses, Matthieu, Hagenkort, Anna, Valerie, Nicholas C. K., Rehling, Daniel, Carter, Megan, Wallner, Olov, Koolmeister, Tobias, Throup, Adam, Jemth, Ann-Sofie, Almlöf, Ingrid, Loseva, Olga, Lundbäck, Thomas, Axelsson, Hanna, Regmi, Shruti, Sarno, Antonio, Krämer, Andreas, Pudelko, Linda, Bräutigam, Lars, Rasti, Azita, Göttmann, Mona, Wiita, Elisée, Kutzner, Juliane, Schaller, Torsten, Kalderén, Christina, Cázares-Körner, Armando, Page, Brent D. G., Krimpenfort, Rosa, Eshtad, Saeed, Altun, Mikael, Rudd, Sean G., Knapp, Stefan, Scobie, Martin, Homan, Evert J., Berglund, Ulrika Warpman, Stenmark, Pål, Helleday, Thomas

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Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily von Digles, Daniela, Ingles-Prieto, Alvaro, Dvorak, Vojtech, Mocking, Tamara A M, Goldmann, Ulrich, Garofoli, Andrea, Homan, Evert J, Di Silvio, Alberto, Azzollini, Lucia, Sassone, Francesca, Fogazza, Mario, Bärenz, Felix, Pommereau, Antje, Zuschlag, Yasmin, Ooms, Jasper F, Tranberg-Jensen, Jeppe, Hansen, Jesper S, Stanka, Josefina, Sijben, Hubert J, Batoulis, Helena, Bender, Eckhard, Martini, Riccardo, IJzerman, Adriaan P, Sauer, David B, Heitman, Laura H, Manolova, Vania, Reinhardt, Juergen, Ehrmann, Alexander, Leippe, Philipp, Ecker, Gerhard F, Huber, Kilian V M, Licher, Thomas, Scarabottolo, Lia, Wiedmer, Tabea, Superti-Furga, Giulio

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Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel von Zhang, Si Min, Paulin, Cynthia B.J., Shu, Huazhang, Yagüe-Capilla, Miriam, Michel, Maurice, Marttila, Petra, Ortis, Florian, Bwanika, Henri Colyn, Dirks, Christopher, Venkatram, Rajagopal Papagudi, Wiita, Elisée, Jemth, Ann-Sofie, Almlöf, Ingrid, Loseva, Olga, Hormann, Femke M., Koolmeister, Tobias, Linde, Erika, Lee, Sun, Llona-Minguez, Sabin, Haraldsson, Martin, Axelsson, Hanna, Strömberg, Kia, Homan, Evert J., Scobie, Martin, Lundbäck, Thomas, Helleday, Thomas, Rudd, Sean G.

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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool von Gad, Helge, Koolmeister, Tobias, Jemth, Ann-Sofie, Eshtad, Saeed, Jacques, Sylvain A., Ström, Cecilia E., Svensson, Linda M., Schultz, Niklas, Lundbäck, Thomas, Einarsdottir, Berglind Osk, Saleh, Aljona, Göktürk, Camilla, Baranczewski, Pawel, Svensson, Richard, Berntsson, Ronnie P.-A., Gustafsson, Robert, Strömberg, Kia, Sanjiv, Kumar, Jacques-Cordonnier, Marie-Caroline, Desroses, Matthieu, Gustavsson, Anna-Lena, Olofsson, Roger, Johansson, Fredrik, Homan, Evert J., Loseva, Olga, Bräutigam, Lars, Johansson, Lars, Höglund, Andreas, Hagenkort, Anna, Pham, Therese, Altun, Mikael, Gaugaz, Fabienne Z., Vikingsson, Svante, Evers, Bastiaan, Henriksson, Martin, Vallin, Karl S. A., Wallner, Olov A., Hammarström, Lars G. J., Wiita, Elisee, Almlöf, Ingrid, Kalderén, Christina, Axelsson, Hanna, Djureinovic, Tatjana, Puigvert, Jordi Carreras, Häggblad, Maria, Jeppsson, Fredrik, Martens, Ulf, Lundin, Cecilia, Lundgren, Bo, Granelli, Ingrid, Jensen, Annika Jenmalm, Artursson, Per, Nilsson, Jonas A., Stenmark, Pål, Scobie, Martin, Berglund, Ulrika Warpman, Helleday, Thomas

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Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function von Michel, Maurice, Benítez-Buelga, Carlos, Calvo, Patricia A., Hanna, Bishoy M. F., Mortusewicz, Oliver, Masuyer, Geoffrey, Davies, Jonathan, Wallner, Olov, Sanjiv, Kumar, Albers, Julian J., Castañeda-Zegarra, Sergio, Jemth, Ann-Sofie, Visnes, Torkild, Sastre-Perona, Ana, Danda, Akhilesh N., Homan, Evert J., Marimuthu, Karthick, Zhenjun, Zhao, Chi, Celestine N., Sarno, Antonio, Wiita, Elisée, von Nicolai, Catharina, Komor, Anna J., Rajagopal, Varshni, Müller, Sarah, Hank, Emily C., Varga, Marek, Scaletti, Emma R., Pandey, Monica, Karsten, Stella, Haslene-Hox, Hanne, Loevenich, Simon, Marttila, Petra, Rasti, Azita, Mamonov, Kirill, Ortis, Florian, Schömberg, Fritz, Loseva, Olga, Stewart, Josephine, D’Arcy-Evans, Nicholas, Koolmeister, Tobias, Henriksson, Martin, Michel, Dana, de Ory, Ana, Acero, Lucia, Calvete, Oriol, Scobie, Martin, Hertweck, Christian, Vilotijevic, Ivan, Kalderén, Christina, Osorio, Ana, Perona, Rosario, Stolz, Alexandra, Stenmark, Pål, Berglund, Ulrika Warpman, de Vega, Miguel, Helleday, Thomas

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Front Cover: The First Structure of Human MTHFD2L and Its Implications for the Development of Isoform‐Selective Inhibitors (ChemMedChem 18/2022) von Scaletti, Emma R., Gustafsson Westergren, Robert, Andersson, Yasmin, Wiita, Elisee, Henriksson, Martin, Homan, Evert J., Jemth, Ann‐Sofie, Helleday, Thomas, Stenmark, Pål

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In silicoDruggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization von Michel, Maurice, Homan, Evert J., Wiita, Elisee, Pedersen, Kia, Almlof, Ingrid, Gustavsson, Anna-Lena, Lundback, Thomas, Helleday, Thomas, Berglund, Ulrika Warpman

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Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1 von Wallner, Olov, Cázares-Körner, Armando, Scaletti, Emma Rose, Masuyer, Geoffrey, Bekkhus, Tove, Visnes, Torkild, Mamonov, Kirill, Ortis, Florian, Lundbäck, Thomas, Volkova, Maria, Koolmeister, Tobias, Wiita, Elisée, Loseva, Olga, Pandey, Monica, Homan, Evert J., Benítez-Buelga, Carlos, Davies, Jonathan, Scobie, Martin, Warpman Berglund, Ulrika, Kalderén, Christina, Stenmark, Pål, Helleday, Thomas, Michel, Maurice

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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress von Bonagas, Nadilly, Gustafsson, Nina M S, Henriksson, Martin, Marttila, Petra, Gustafsson, Robert, Wiita, Elisée, Borhade, Sanjay, Green, Alanna C, Vallin, Karl S A, Sarno, Antonio, Svensson, Richard, Göktürk, Camilla, Pham, Therese, Jemth, Ann-Sofie, Loseva, Olga, Cookson, Victoria, Kiweler, Nicole, Sandberg, Lars, Rasti, Azita, Unterlass, Judith E, Haraldsson, Martin, Andersson, Yasmin, Scaletti, Emma R, Bengtsson, Christoffer, Paulin, Cynthia B J, Sanjiv, Kumar, Abdurakhmanov, Eldar, Pudelko, Linda, Kunz, Ben, Desroses, Matthieu, Iliev, Petar, Färnegårdh, Katarina, Krämer, Andreas, Garg, Neeraj, Michel, Maurice, Häggblad, Sara, Jarvius, Malin, Kalderén, Christina, Jensen, Amanda Bögedahl, Almlöf, Ingrid, Karsten, Stella, Zhang, Si Min, Häggblad, Maria, Eriksson, Anders, Liu, Jianping, Glinghammar, Björn, Nekhotiaeva, Natalia, Klingegård, Fredrik, Koolmeister, Tobias, Martens, Ulf, Llona-Minguez, Sabin, Moulson, Ruth, Nordström, Helena, Parrow, Vendela, Dahllund, Leif, Sjöberg, Birger, Vargas, Irene L, Vo, Duy Duc, Wannberg, Johan, Knapp, Stefan, Krokan, Hans E, Arvidsson, Per I, Scobie, Martin, Meiser, Johannes, Stenmark, Pål, Berglund, Ulrika Warpman, Homan, Evert J, Helleday, Thomas

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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation von Visnes, Torkild, Armando, Cazares-Körner, Wenjing, Hao, Wallner, Olov, Masuyer, Geoffrey, Loseva, Olga, Mortusewicz, Oliver, Wiita, Elisee, Sarno, Antonio, Manoilov, Aleksandr, Astorga-Wells, Juan, Jemth, Ann-Sofie, Pan, Lang, Sanjiv, Kumar, Karsten, Stella, Gokturk, Camilla, Grube, Maurice, Evert J, Homan, Hanna, Bishoy Magdi Fekry, Cynthia, Paulin BJ, pham, Therese, Rasti, Azita, Warpman Berglund, Ulrika, von Nikolai, Catharina, Benitez-Buelga, Carlos, Koolmeister, Tobias, Ivanic, Dag, Iliev, Petar, Scobie, Martin, Krokan, Hans Einar, Baranczewski, Pawel, Artursson, Per, Altun, Mikael, Jenmalm-Jensen, Annika, Kalderen, Christina, Xueqing, Ba, Zubarev, Roman A., Stenmark, Pål, Boldogh, Istvan, Helleday, Thomas

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Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation von Visnes, Torkild, Armando, Cazares-Körner, Wenjing, Hao, Wallner, Olov, Masuyer, Geoffrey, Loseva, Olga, Mortusewicz, Oliver, Wiita, Elisee, Sarno, Antonio, Manoilov, Aleksandr, Astorga-Wells, Juan, Jemth, Ann-Sofie, Pan, Lang, Sanjiv, Kumar, Karsten, Stella, Gokturk, Camilla, Grube, Maurice, Evert J, Homan, Hanna, Bishoy Magdi Fekry, Cynthia, Paulin BJ, pham, Therese, Rasti, Azita, Warpman Berglund, Ulrika, von Nikolai, Catharina, Benitez-Buelga, Carlos, Koolmeister, Tobias, Ivanic, Dag, Iliev, Petar, Scobie, Martin, Krokan, Hans Einar, Baranczewski, Pawel, Artursson, Per, Altun, Mikael, Jenmalm-Jensen, Annika, Kalderen, Christina, Xueqing, Ba, Zubarev, Roman A., Stenmark, Pål, Boldogh, Istvan, Helleday, Thomas

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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool (vol 508, pg 215, 2014) von Gad, H, Koolmeister, T, Jemth, A-S, Eshtad, S, Jacques, SA, Strom, CE, Svensson, LM, Schultz, N, Lundback, T, Einarsdottir, BO

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