Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis von Verma, Nandini, Müller, Anna-Katharina, Kothari, Charu, Panayotopoulou, Effrosini, Kedan, Amir, Selitrennik, Michael, Mills, Gordon B, Nguyen, Lan K, Shin, Sungyoung, Karn, Thomas, Holtrich, Uwe, Lev, Sima

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Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer von Ruckhäberle, Eugen, Rody, Achim, Engels, Knut, Gaetje, Regine, von Minckwitz, Gunter, Schiffmann, Susanne, Grösch, Sabine, Geisslinger, Gerd, Holtrich, Uwe, Karn, Thomas, Kaufmann, Manfred

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Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures von Karn, Thomas, Pusztai, Lajos, Holtrich, Uwe, Iwamoto, Takayuki, Shiang, Christine Y, Schmidt, Marcus, Müller, Volkmar, Solbach, Christine, Gaetje, Regine, Hanker, Lars, Ahr, Andre, Liedtke, Cornelia, Ruckhäberle, Eugen, Kaufmann, Manfred, Rody, Achim

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Histotype-specific analysis of acid ceramidase expression in ovarian cancer von El-Balat, Ahmed, Karn, Thomas, Holtrich, Uwe, Becker, Sven, Kommoss, Stefan, Győrffy, Balázs, Anglesio, Michael S., Huntsman, David G., Drosos, Zacharias, Rody, Achim, Gevensleben, Heidrun, Hanker, Lars C.

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Molecular differences between younger versus older ER-positive and HER2-negative breast cancers von Qing, Tao, Karn, Thomas, Rozenblit, Mariya, Foldi, Julia, Marczyk, Michal, Shan, Naing Lin, Blenman, Kim, Holtrich, Uwe, Kalinsky, Kevin, Meric-Bernstam, Funda, Pusztai, Lajos

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Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers von Bianchini, Giampaolo, Pusztai, Lajos, Karn, Thomas, Iwamoto, Takayuki, Rody, Achim, Kelly, Catherine, Müller, Volkmar, Schmidt, Schmidt, Qi, Yuan, Holtrich, Uwe, Becker, Sven, Santarpia, Libero, Fasolo, Angelica, Del Conte, Gianluca, Zambetti, Milvia, Sotiriou, Christos, Haibe-Kains, Benjamin, Symmans, W Fraser, Gianni, Luca

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Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation von Karn, Thomas, Pusztai, Lajos, Ruckhäberle, Eugen, Liedtke, Cornelia, Müller, Volkmar, Schmidt, Marcus, Metzler, Dirk, Wang, Jing, Coombes, Kevin R, Gätje, Regine, Hanker, Lars, Solbach, Christine, Ahr, Andre, Holtrich, Uwe, Rody, Achim, Kaufmann, Manfred

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Characterization of WNT7A expression in human endometrium and endometriotic lesions von Gaetje, Regine, M.D, Holtrich, Uwe, Ph.D, Karn, Thomas, Ph.D, Cikrit, Eva, Engels, Knut, M.D, Rody, Achim, M.D, Kaufmann, Manfred, M.D

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Identification of high risk breast-cancer patients by gene expression profiling von Ahr, André, Karn, Thomas, Solbach, Christine, Seiter, Tanja, Strebhardt, Klaus, Holtrich, Uwe, Kaufmann, Manfred

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Prognostic significance of polo-like kinase (PLK) expression in non-small cell lung cancer von WOLF, G, ELEZ, R, DOERMER, A, HOLTRICH, U, ACKERMANN, H, STUTTE, H. J, ALTMANNSBERGER, H.-M, RÜBSAMEN-WAIGMANN, H, STREBHARDT, K

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Poor Outcome in Estrogen Receptor–Positive Breast Cancers Predicted by Loss of Plexin B1 von RODY, Achim, HOLTRICH, Uwe, AHR, Andre, SOLBACH, Christine, KARN, Thomas, KAUFMANN, Manfred, GAETJE, Regine, GEHRMANN, Mathias, ENGELS, Knut, VON MINCKWITZ, Gunter, LOIBL, Sibylle, DIALLO-DANEBROCK, Raihanatou, RUCKHÄBERLE, Eugen, METZLER, Dirk

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FSCN1 as prognostic marker in borderline tumors of the ovary von El-Balat, Ahmed, Holtrich, Uwe, Karn, Thomas, Becker, Sven

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PDZ-Domain-Mediated Interaction of the Eph-Related Receptor Tyrosine Kinase EphB3 and the Ras-Binding Protein AF6 Depends on the Kinase Activity of the Receptor von Hock, Bjorn, Bohme, Beatrix, Karn, Thomas, Yamamoto, Takaharu, Kaibuchi, Kozo, Holtrich, Uwe, Holland, Sacha, Pawson, Tony, Rubsamen-Waigmann, Helga, Strebhardt, Klaus

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Endometriosis may be generated by mimicking the ontogenetic development of the female genital tract von Gaetje, Regine, M.D, Holtrich, Uwe, Ph.D, Engels, Knut, M.D, Kissler, Stefan, M.D, Rody, Achim, M.D, Karn, Thomas, Ph.D, Kaufmann, Manfred, M.D

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Control of dataset bias in combined Affymetrix cohorts of triple negative breast cancer von Karn, Thomas, Rody, Achim, Müller, Volkmar, Schmidt, Marcus, Becker, Sven, Holtrich, Uwe, Pusztai, Lajos

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T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers von Rody, Achim, Holtrich, Uwe, Pusztai, Laos, Liedtke, Cornelia, Gaetje, Regine, Ruckhaeberle, Eugen, Solbach, Christine, Hanker, Lars, Ahr, Andre, Metzler, Dirk, Engels, Knut, Karn, Thomas, Kaufmann, Manfred

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Molecular classification of breast cancer patients by gene expression profiling von Ahr, André, Holtrich, Uwe, Solbach, Christine, Scharl, Anton, Strebhardt, Klaus, Karn, Thomas, Kaufmann, Manfred

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A clinically relevant gene signature in triple negative and basal-like breast cancer von Rody, Achim, Karn, Thomas, Liedtke, Cornelia, Pusztai, Lajos, Ruckhaeberle, Eugen, Hanker, Lars, Gaetje, Regine, Solbach, Christine, Ahr, Andre, Metzler, Dirk, Schmidt, Marcus, Müller, Volkmar, Holtrich, Uwe, Kaufmann, Manfred

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The prognostic impact of age in different molecular subtypes of breast cancer von Liedtke, Cornelia, Rody, Achim, Gluz, Oleg, Baumann, Kristin, Beyer, Daniel, Kohls, Eva-Beatrice, Lausen, Kerstin, Hanker, Lars, Holtrich, Uwe, Becker, Sven, Karn, Thomas

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Low TMB as predictor for additional benefit from neoadjuvant immune checkpoint inhibition in triple-negative breast cancer von Karn, Thomas, Denkert, Carsten, Rey, Julia, Weber, Karsten Ernst, Holtrich, Uwe, Hanusch, Claus, Sinn, Bruno Valentin, Jank, Paul, Huober, Jens Bodo, Blohmer, Jens U., Schmitt, Wolfgang D., van Mackelenbergh, Marion, Schem, Christian, Stickeler, Elmar, Jackisch, Christian, Untch, Michael, Schneeweiss, Andreas, Loibl, Sibylle

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