Cellular mechanisms and physiological consequences of redox-dependent signalling von Holmström, Kira M., Finkel, Toren

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Nrf2 regulates ROS production by mitochondria and NADPH oxidase von Kovac, Stjepana, Angelova, Plamena R., Holmström, Kira M., Zhang, Ying, Dinkova-Kostova, Albena T., Abramov, Andrey Y.

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HER-096 is a CDNF-derived brain-penetrating peptidomimetic that protects dopaminergic neurons in a mouse synucleinopathy model of Parkinson’s disease von Kulesskaya, Natalia, Bhattacharjee, Arnab, Holmström, Kira M., Vuorio, Päivi, Henriques, Alexandre, Callizot, Noëlle, Huttunen, Henri J.

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Measuring In Vivo Mitophagy von Sun, Nuo, Yun, Jeanho, Liu, Jie, Malide, Daniela, Liu, Chengyu, Rovira, Ilsa I., Holmström, Kira M., Fergusson, Maria M., Yoo, Young Hyun, Combs, Christian A., Finkel, Toren

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MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload von Liu, Julia C., Liu, Jie, Holmström, Kira M., Menazza, Sara, Parks, Randi J., Fergusson, Maria M., Yu, Zu-Xi, Springer, Danielle A., Halsey, Charles, Liu, Chengyu, Murphy, Elizabeth, Finkel, Toren

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 von Fiesel, Fabienne C, Geisler, Sven, Kahle, Philipp J, Springer, Wolfdieter, Skujat, Diana, Rothfuss, Oliver C, Holmström, Kira M

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The Ins and Outs of Mitochondrial Calcium von Finkel, Toren, Menazza, Sara, Holmström, Kira M, Parks, Randi J, Liu, Julia, Sun, Junhui, Liu, Jie, Pan, Xin, Murphy, Elizabeth

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Mutations in ANO3 Cause Dominant Craniocervical Dystonia: Ion Channel Implicated in Pathogenesis von Charlesworth, Gavin, Plagnol, Vincent, Holmström, Kira M., Bras, Jose, Sheerin, Una-Marie, Preza, Elisavet, Rubio-Agusti, Ignacio, Ryten, Mina, Schneider, Susanne A., Stamelou, Maria, Trabzuni, Daniah, Abramov, Andrey Y., Bhatia, Kailash P., Wood, Nicholas W.

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Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration von Holmström, Kira M, Baird, Liam, Zhang, Ying, Hargreaves, Iain, Chalasani, Annapurna, Land, John M, Stanyer, Lee, Yamamoto, Masayuki, Dinkova-Kostova, Albena T, Abramov, Andrey Y

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Rare Individual Amyloid‑β Oligomers Act on Astrocytes to Initiate Neuronal Damage von Narayan, Priyanka, Holmström, Kira M, Kim, Dong-Hyun, Whitcomb, Daniel J, Wilson, Mark R, St. George-Hyslop, Peter, Wood, Nicholas W, Dobson, Christopher M, Cho, Kwangwook, Abramov, Andrey Y, Klenerman, David

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The multifaceted role of Nrf2 in mitochondrial function von Holmström, Kira M., Kostov, Rumen V., Dinkova-Kostova, Albena T.

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Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter von Holmström, Kira M, Pan, Xin, Liu, Julia C, Menazza, Sara, Liu, Jie, Nguyen, Tiffany T, Pan, Haihui, Parks, Randi J, Anderson, Stasia, Noguchi, Audrey, Springer, Danielle, Murphy, Elizabeth, Finkel, Toren

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The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations von Geisler, Sven, Holmström, Kira M, Treis, Angela, Skujat, Diana, Weber, Stephanie S, Fiesel, Fabienne C, Kahle, Philipp J, Springer, Wolfdieter

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Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson's disease von Kulesskaya, Natalia, Holmström, Kira M, Huttunen, Henri J

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Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology von Szibor, Marten, Dhandapani, Praveen K, Dufour, Eric, Holmström, Kira M, Zhuang, Yuan, Salwig, Isabelle, Wittig, Ilka, Heidler, Juliana, Gizatullina, Zemfira, Gainutdinov, Timur, Fuchs, Helmut, Gailus-Durner, Valérie, de Angelis, Martin Hrabě, Nandania, Jatin, Velagapudi, Vidya, Wietelmann, Astrid, Rustin, Pierre, Gellerich, Frank N, Jacobs, Howard T, Braun, Thomas

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EMRE is essential for mitochondrial calcium uniporter activity in a mouse model von Liu, Julia C, Syder, Nicole C, Ghorashi, Nima S, Willingham, Thomas B, Parks, Randi J, Sun, Junhui, Fergusson, Maria M, Liu, Jie, Holmström, Kira M, Menazza, Sara, Springer, Danielle A, Liu, Chengyu, Glancy, Brian, Finkel, Toren, Murphy, Elizabeth

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Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter von Parks, Randi J, Menazza, Sara, Holmström, Kira M, Amanakis, Georgios, Fergusson, Maria, Ma, Hanley, Aponte, Angel M, Bernardi, Paolo, Finkel, Toren, Murphy, Elizabeth

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Acetylcholine and antibodies against the acetylcholine receptor protect neurons and astrocytes against beta-amyloid toxicity von Kamynina, Anna V., Holmström, Kira M., Koroev, Dmitriy O., Volpina, Olga M., Abramov, Andrey Y.

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Unresolved questions from the analysis of mice lacking MCU expression von Murphy, Elizabeth, Pan, Xin, Nguyen, Tiffany, Liu, Jie, Holmström, Kira M., Finkel, Toren

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Signalling properties of inorganic polyphosphate in the mammalian brain von Holmström, Kira M., Marina, Nephtali, Baev, Artyom Y., Wood, Nicholas W., Gourine, Alexander V., Abramov, Andrey Y.

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