Chemically Catalyzed Asymmetric Cyanohydrin Syntheses von Brunel, Jean-Michel, Holmes, Ian P.

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Palladium‐Catalyzed Tandem Alkenyl and Aryl CN Bond Formation: A Cascade N‐Annulation Route to 1‐Functionalized Indoles von Willis, Michael C., Brace, Gareth N., Holmes, Ian P.

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Characterization of the Novel Broad-Spectrum Kinase Inhibitor CTx-0294885 As an Affinity Reagent for Mass Spectrometry-Based Kinome Profiling von Zhang, Luxi, Holmes, Ian P, Hochgräfe, Falko, Walker, Scott R, Ali, Naveid A, Humphrey, Emily S, Wu, Jianmin, de Silva, Melanie, Kersten, Wilhelmus J. A, Connor, Theresa, Falk, Hendrik, Allan, Lynda, Street, Ian P, Bentley, John D, Pilling, Patricia A, Monahan, Brendon J, Peat, Thomas S, Daly, Roger J

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2-(2-Haloalkenyl)-aryl Halides as Substrates for Palladium-Catalysed Tandem CN Bond Formation: Efficient Synthesis of 1-Substituted Indoles von Willis, Michael C., Brace, Gareth N., Findlay, Thomas J. K., Holmes, Ian P.

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The asymmetric addition of trimethylsilylcyanide to aldehydes catalysed by anionic chiral nucleophiles. Part 1 von Holmes, Ian P, Kagan, Henri B

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The asymmetric addition of trimethylsilylcyanide to aldehydes catalysed by anionic chiral nucleophiles. Part 2 von Holmes, Ian P, Kagan, Henri B

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The identification of a series of novel, soluble non-peptidic neuropeptide Y Y2 receptor antagonists von Lunniss, Gillian E., Barnes, Ashley A., Barton, Nick, Biagetti, Matteo, Bianchi, Federica, Blowers, Stephen M., Caberlotto, Laura L., Emmons, Amanda, Holmes, Ian P., Montanari, Dino, Norris, Roz, Puckey, Gemma V., Walters, Dewi J., Watson, Steve P., Willis, John

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Dopamine D3 receptor antagonists: The quest for a potentially selective PET ligand. Part one: Lead identification von HOLMES, Ian P, MICHELI, Fabrizio, GAINES, Simon, LORTHIOIR, Olivier, WATSON, Steve P, DI FABIO, Romano, GENTILE, Gabriella, HEIDBREDER, Christian, SAVOIA, Chiara, WORBY, Angela

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The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists von Lunniss, Gillian E., Barnes, Ashley A., Barton, Nick, Biagetti, Matteo, Bianchi, Federica, Blowers, Stephen M., Caberlotto, Laura, Emmons, Amanda, Holmes, Ian P., Montanari, Dino, Norris, Ros, Walters, Dewi J., Watson, Steve P.

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The identification of β-hydroxy carboxylic acids as selective MMP-12 inhibitors von Holmes, Ian P., Gaines, Simon, Watson, Steve P., Lorthioir, Olivier, Walker, Adam, Baddeley, Suzanne J., Herbert, Shane, Egan, Danielle, Convery, Máire A., Singh, Onkar M.P., Gross, Jeffrey W., Strelow, John M., Smith, Robert H., Amour, Augustin J., Brown, David, Martin, Stephen L.

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The identification of a selective dopamine D2 partial agonist, D3 antagonist displaying high levels of brain exposure von HOLMES, Ian P, BLUNT, Richard J, HOWES, Claire M, MICHELI, Fabrizio, DI FABIO, Romano, DONATI, Daniele, TERRENI, Silvia, HAMPRECHT, Dieter, ARISTA, Luca, WORBY, Angela, WATSON, Steve P, LORTHIOIR, Olivier E, BLOWERS, Stephen M, GRIBBLE, Andy, PAYNE, Andrew H, STANSFIELD, Ian G, WOOD, Martyn, WOOLLARD, Patrick M, REAVILL, Charlie

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A simple, user-friendly process for the homologation of aldehydes using tosylhydrazone salts von Aggarwal, Varinder K, de Vicente, Javier, Pelotier, Beatrice, Holmes, Ian P, Bonnert, Roger V

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Palladium-Catalyzed Tandem Alkenyl and Aryl CN Bond Formation: A Cascade N-Annulation Route to 1-Functionalized Indoles von Willis, Michael C., Brace, Gareth N., Holmes, Ian P.

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Efficient Palladium-Catalysed Enamide Synthesis from Enol Triflates and Enol Tosylates von Willis, Michael C., Brace, Gareth N., Holmes, Ian P.

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Abstract 5371: PRMT5 inhibitors as novel treatment for cancers von Falk, Hendrik, Foitzik, Richard C., Allan, Elizabeth, deSilva, Melanie, Yang, Hong, Bozikis, Ylva E., Nikac, Marica, Walker, Scott R., Camerino, Michelle A., Morrow, Ben J., Stupple, Alexandra E., Lagiakos, Rachel, Pinson, Jo-Anne, Lessene, Romina, Kersten, Wilhelmus JA, Ganame, Danny G., Holmes, Ian P., Lunniss, Gill E., Chung, Matthew, Hermans, Stefan J., Parker, Michael W., Thistlethwaite, Alison, White, Karen, Charman, Susan A., Monahan, Brendon J., Pilling, Patricia, Grusovin, Julian, Peat, Thomas S., Sonderegger, Stefan, Toulmin, Emma, Jane, Stephen M., Curtis, David J., Stupple, Paul A., Street, Ian P.

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Dopamine D 3 receptor antagonists: The quest for a potentially selective PET ligand. Part one: Lead identification von Holmes, Ian P., Micheli, Fabrizio, Gaines, Simon, Lorthioir, Olivier, Watson, Steve P., Fabio, Romano Di, Gentile, Gabriella, Heidbreder, Christian, Savoia, Chiara, Worby, Angela

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The identification of a selective dopamine D 2 partial agonist, D 3 antagonist displaying high levels of brain exposure von Holmes, Ian P., Blunt, Richard J., Lorthioir, Olivier E., Blowers, Stephen M., Gribble, Andy, Payne, Andrew H., Stansfield, Ian G., Wood, Martyn, Woollard, Patrick M., Reavill, Charlie, Howes, Claire M., Micheli, Fabrizio, Fabio, Romano Di, Donati, Daniele, Terreni, Silvia, Hamprecht, Dieter, Arista, Luca, Worby, Angela, Watson, Steve P.

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The identification of a selective dopamine D sub(2) partial agonist, D sub(3) antagonist displaying high levels of brain exposure von Holmes, Ian P, Blunt, Richard J, Lorthioir, Olivier E, Blowers, Stephen M, Gribble, Andy, Payne, Andrew H, Stansfield, Ian G, Wood, Martyn, Woollard, Patrick M, Reavill, Charlie, Howes, Claire M, Micheli, Fabrizio, Di Fabio, Romano, Donati, Daniele, Terreni, Silvia, Hamprecht, Dieter, Arista, Luca, Worby, Angela, Watson, Steve P

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Chemisch katalysierte asymmetrische Cyanhydrinsynthesen von Brunel, Jean-Michel, Holmes, Ian P.

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Palladium-Catalyzed Tandem Alkenyl and Aryl CN Bond Formation: A Cascade N-Annulation Route to 1-Functionalized Indoles von Willis, Michael C., Brace, Gareth N., Holmes, Ian P.

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