EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer von KOIVUNEN, Jussi P, MERMEL, Craig, LEE, Jinseon, RICHARDS, William G, SUGARBAKER, David J, DUCKO, Christopher, LINDEMAN, Neal, MARCOUX, J. Paul, ENGELMAN, Jeffrey A, GRAY, Nathanael S, LEE, Charles, MEYERSON, Matthew, ZEJNULLAHU, Kreshnik, JDNNE, Pasi A, MURPHY, Carly, LIFSHITS, Eugene, HOLMES, Alison J, HWAN GEUN CHOI, KIRN, Jhingook, CHIANG, Derek, THOMAS, Roman

Volltext

Exon 19 Deletion Mutations of Epidermal Growth Factor Receptor Are Associated with Prolonged Survival in Non–Small Cell Lung Cancer Patients Treated with Gefitinib or Erlotinib von Jackman, David M, Yeap, Beow Y, Sequist, Lecia V, Lindeman, Neal, Holmes, Alison J, Joshi, Victoria A, Bell, Daphne W, Huberman, Mark S, Halmos, Balazs, Rabin, Michael S, Haber, Daniel A, Lynch, Thomas J, Meyerson, Matthew, Johnson, Bruce E, Jänne, Pasi A

Volltext

Factors associated with depressive symptoms in cancer family caregivers of patients receiving chemotherapy von Williams, Anna-leila, Tisch, Alison J. Holmes, Dixon, Jane, McCorkle, Ruth

Volltext

Phase II Clinical Trial of Chemotherapy-Naïve Patients ≥ 70 Years of Age Treated With Erlotinib for Advanced Non–Small-Cell Lung Cancer von JACKMAN, David M, YEAP, Beow Y, FREIDLIN, Boris, OSTLER, Patricia A, LUCCA, Joan, LYNCH, Thomas J, JOHNSON, Bruce E, JDNNE, Pasi A, LINDEMAN, Neal I, FIDIAS, Panos, RABIN, Michael S, TEMEL, Jennifer, SKARIN, Arthur T, MEYERSON, Matthew, HOLMES, Alison J, BORRAS, Ana M

Volltext

Prospective Study of Gefitinib in Epidermal Growth Factor Receptor Fluorescence In Situ Hybridization–Positive/Phospho-Akt–Positive or Never Smoker Patients With Advanced Non–Small... von CAPPUZZO, Federico, LIGORIO, Claudia, BARTOLINI, Stefania, CANCELLIERI, Alessandra, CIARDIELLO, Fortunato, PATELLI, Marco, CRINO, Lucio, VARELLA-GARCIA, Marileila, JÄNNE, Pasi A, TOSCHI, Luca, ROSSI, Elisa, TRISOLINI, Rocco, PAIOLI, Daniela, HOLMES, Alison J, MAGRINI, Elisabetta, FINOCCHIARO, Giovanna

Volltext

MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling von Engelman, Jeffrey A, Zejnullahu, Kreshnik, Mitsudomi, Tetsuya, Song, Youngchul, Hyland, Courtney, Park, Joon Oh, Lindeman, Neal, Gale, Christopher-Michael, Zhao, Xiaojun, Christensen, James, Kosaka, Takayuki, Holmes, Alison J, Rogers, Andrew M, Cappuzzo, Federico, Mok, Tony, Lee, Charles, Johnson, Bruce E, Cantley, Lewis C, Jänne, Pasi A

Volltext

Are There Any Ethnic Differences in Molecular Predictors of Erlotinib Efficacy in Advanced Non-Small Cell Lung Cancer? von Ahn, Myung-Ju, Park, Byeong-Bae, Ahn, Jin Seok, Kim, Sang We, Kim, Heung-Tae, Lee, Jong Seog, Kang, Jin Hyung, Cho, Jae Yong, Song, Hong Suk, Park, Se Hoon, Sohn, Chang Hak, Shin, Sang Won, Choi, Jin Hyuck, Ki, Chang-Seok, Park, Chan Keum, Holmes, Alison J, Jänne, Pasi A, Park, Keunchil

Volltext

Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinib von JACKMAN, David M, HOLMES, Alison J, LINDEMAN, Neal, WEN, Patrick Y, KESARI, Santosh, BORRAS, Ana M, BAILEY, Christopher, DE JONG, Francisca, JÄNNE, Pasi A, JOHNSON, Bruce E

Volltext

Pruritus as a Paraneoplastic Symptom of Thymoma von Padda, Sukhmani K., Shrager, Joseph B., Riess, Jonathan W., Pagtama, Judy Y., Tisch, Alison J. Holmes, Kwong, Bernice Y., Liang, Ying, Schwartz, Erich J., Loo, Billy W., Neal, Joel W., Hardy, Russell, Wakelee, Heather A.

Volltext

Ultra deep sequencing detects a low rate of mosaic mutations in tuberous sclerosis complex von Qin, Wei, Kozlowski, Piotr, Taillon, Bruce E, Bouffard, Pascal, Holmes, Alison J, Janne, Pasi, Camposano, Susana, Thiele, Elizabeth, Franz, David, Kwiatkowski, David J

Volltext

Injectional anthrax infection due to heroin use induces strong immunological memory von Ascough, Stephanie, Ingram, Rebecca J, Abarra, Aula, Holmes, Alison J, Maillere, Bernard, Altmann, Daniel M, Boyton, Rosemary J

Volltext

Discordance of Molecular Biomarkers Associated with Epidermal Growth Factor Receptor Pathway between Primary Tumors and Lymph Node Metastasis in Non-small Cell Lung Cancer von Park, Sarah, Holmes-Tisch, Alison J., cho, Eun Yoon, Shim, Young Mog, Kim, Jinkook, Kim, Hyo Song, Lee, Jeeyun, Park, Yeon Hee, Ahn, Jin Seok, Park, Keunchil, Jänne, Pasi A., Ahn, Myung-Ju

Volltext

Lung adenocarcinoma with EGFR amplification has distinct clinicopathologic and molecular features in never-smokers von Sholl, Lynette M, Yeap, Beow Y, Iafrate, A John, Holmes-Tisch, Alison J, Chou, Yi-Ping, Wu, Ming-Tsang, Goan, Yih-Gang, Su, Li, Benedettini, Elisa, Yu, Jian, Loda, Massimo, Jänne, Pasi A, Christiani, David C, Chirieac, Lucian R

Volltext

Understanding the mechanisms and drivers of antimicrobial resistance von Holmes, Alison H, Prof, Moore, Luke S P, MPH, Sundsfjord, Arnfinn, MD, Steinbakk, Martin, MD, Regmi, Sadie, MBChB, Karkey, Abhilasha, DPhil, Guerin, Philippe J, MD, Piddock, Laura J V, PhD

Volltext

COVID-19 and the potential long-term impact on antimicrobial resistance von Rawson, Timothy M, Moore, Luke S P, Castro-Sanchez, Enrique, Charani, Esmita, Davies, Frances, Satta, Giovanni, Ellington, Matthew J, Holmes, Alison H

Volltext

International cooperation to improve access to and sustain effectiveness of antimicrobials von Årdal, Christine, MBA, Outterson, Kevin, Prof, Hoffman, Steven J, JD, Ghafur, Abdul, Prof, Sharland, Mike, FRCPCH, Ranganathan, Nisha, MRCP, Smith, Richard, Prof, Zorzet, Anna, PhD, Cohn, Jennifer, MD, Pittet, Didier, Prof, Daulaire, Nils, MD, Morel, Chantal, MSc, Rizvi, Zain, BHSc, Balasegaram, Manica, MD, Dar, Osman A, FFPH, Heymann, David L, Prof, Holmes, Alison H, Prof, Moore, Luke S P, MPH, Laxminarayan, Ramanan, PhD, Mendelson, Marc, Prof, Røttingen, John-Arne, Prof

Volltext

Improving the estimation of the global burden of antimicrobial resistant infections von Limmathurotsakul, Direk, Dunachie, Susanna, Fukuda, Keiji, Feasey, Nicholas A, Okeke, Iruka N, Holmes, Alison H, Moore, Catrin E, Dolecek, Christiane, van Doorn, H Rogier, Shetty, Nandini, Lopez, Alan D, Peacock, Sharon J

Volltext

An analysis of existing national action plans for antimicrobial resistance—gaps and opportunities in strategies optimising antibiotic use in human populations von Charani, Esmita, Mendelson, Marc, Pallett, Scott J C, Ahmad, Raheelah, Mpundu, Mirfin, Mbamalu, Oluchi, Bonaconsa, Candice, Nampoothiri, Vrinda, Singh, Sanjeev, Peiffer-Smadja, Nathan, Anton-Vazquez, Vanesa, Moore, Luke S P, Schouten, Jeroen, Kostyanev, Tomislav, Vlahović-Palčevski, Vera, Kofteridis, Diamantis, Corrêa, Juliana Silva, Holmes, Alison H

Volltext

Engineering Two-Phase and Three-Phase Microstructures from Water-Based Dispersions of Nanoparticles for Eco-Friendly Polymer Solar Cell Applications von Holmes, Natalie P, Marks, Melissa, Cave, James M, Feron, Krishna, Barr, Matthew G, Fahy, Adam, Sharma, Anirudh, Pan, Xun, Kilcoyne, David A. L, Zhou, Xiaojing, Lewis, David A, Andersson, Mats R, van Stam, Jan, Walker, Alison B, Moons, Ellen, Belcher, Warwick J, Dastoor, Paul C

Volltext

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery von Lee, E-Chiang, Liang, Qi, Ali, Hanif, Bayliss, Luke, Beasley, Alastair, Bloomfield-Gerdes, Tara, Bonoli, Laura, Brown, Richard, Campbell, Jamie, Carpenter, Adam, Chalk, Sara, Davis, Alison, England, Nick, Fane-Dremucheva, Alla, Franz, Bettina, Germaschewski, Volker, Holmes, Helen, Holmes, Steve, Kirby, Ian, Kosmac, Miha, Legent, Anais, Lui, Hui, Manin, Anais, O'Leary, Siobhan, Paterson, Jemima, Sciarrillo, Rocco, Speak, Anneliese, Spensberger, Dominik, Tuffery, Laura, Waddell, Nikole, Wang, Wei, Wells, Sophie, Wong, Vivian, Wood, Andrew, Owen, Michael J, Friedrich, Glenn A, Bradley, Allan

Volltext