AKT1 Activation Promotes Development of Melanoma Metastases von Cho, Joseph H., Robinson, James P., Arave, Rowan A., Burnett, William J., Kircher, David A., Chen, Guo, Davies, Michael A., Grossmann, Allie H., VanBrocklin, Matthew W., McMahon, Martin, Holmen, Sheri L.

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Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma von Yu, Yong, Schleich, Kolja, Yue, Bin, Ji, Sujuan, Lohneis, Philipp, Kemper, Kristel, Silvis, Mark R., Qutob, Nouar, van Rooijen, Ellen, Werner-Klein, Melanie, Li, Lianjie, Dhawan, Dhriti, Meierjohann, Svenja, Reimann, Maurice, Elkahloun, Abdel, Treitschke, Steffi, Dörken, Bernd, Speck, Christian, Mallette, Frédérick A., Zon, Leonard I., Holmen, Sheri L., Peeper, Daniel S., Samuels, Yardena, Schmitt, Clemens A., Lee, Soyoung

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Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines von Valiente, Manuel, Van Swearingen, Amanda E. D., Anders, Carey K., Bairoch, Amos, Boire, Adrienne, Bos, Paula D., Cittelly, Diana M., Erez, Neta, Ferraro, Gino B., Fukumura, Dai, Gril, Brunilde, Herlyn, Meenhard, Holmen, Sheri L., Jain, Rakesh K., Joyce, Johanna A., Lorger, Mihaela, Massague, Joan, Neman, Josh, Sibson, Nicola R., Steeg, Patricia S., Thorsen, Frits, Young, Leonie S., Vareslija, Damir, Vultur, Adina, Weis-Garcia, Frances, Winkler, Frank

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Mutant IDH1 Promotes Glioma Formation In Vivo von Philip, Beatrice, Yu, Diana X., Silvis, Mark R., Shin, Clifford H., Robinson, James P., Robinson, Gemma L., Welker, Adam E., Angel, Stephanie N., Tripp, Sheryl R., Sonnen, Joshua A., VanBrocklin, Matthew W., Gibbons, Richard J., Looper, Ryan E., Colman, Howard, Holmen, Sheri L.

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Melanoma Brain Metastasis: Mechanisms, Models, and Medicine von Kircher, David A, Silvis, Mark R, Cho, Joseph H, Holmen, Sheri L

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Tumour-intrinsic endomembrane trafficking by ARF6 shapes an immunosuppressive microenvironment that drives melanomagenesis and response to checkpoint blockade therapy von Wee, Yinshen, Wang, Junhua, Wilson, Emily C., Rich, Coulson P., Rogers, Aaron, Tong, Zongzhong, DeGroot, Evelyn, Gopal, Y. N. Vashisht, Davies, Michael A., Ekiz, H. Atakan, Tay, Joshua K. H., Stubben, Chris, Boucher, Kenneth M., Oviedo, Juan M., Fairfax, Keke C., Williams, Matthew A., Holmen, Sheri L., Wolff, Roger K., Grossmann, Allie H.

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IDH1 and IDH2 Mutations in Gliomas von Cohen, Adam L., Holmen, Sheri L., Colman, Howard

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Reduced Affinity to and Inhibition by DKK1 Form a Common Mechanism by Which High Bone Mass-Associated Missense Mutations in LRP5 Affect Canonical Wnt Signaling von Ai, Minrong, Holmen, Sheri L., Van Hul, Wim, Williams, Bart O., Warman, Matthew L.

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Decreased BMD and Limb Deformities in Mice Carrying Mutations in Both Lrp5 and Lrp6 von Holmen, Sheri L, Giambernardi, Troy A, Zylstra, Cassandra R, Buckner‐Berghuis, Bree D, Resau, James H, Hess, J Fred, Glatt, Vaida, Bouxsein, Mary L, Ai, Minrong, Warman, Matthew L, Williams, Bart O

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Mitogen-Activated Protein Kinase Inhibition Induces Translocation of Bmf to Promote Apoptosis in Melanoma von VANBROCKLIN, Matthew W, VERHAEGEN, Monique, SOENGAS, Maria S, HOLMEN, Sheri L

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First line immunotherapy extends brain metastasis free survival, improves overall survival, and reduces the incidence of brain metastasis in patients with advanced melanoma von Wang, Xuechen, Haaland, Benjamin, Hu‐Lieskovan, Siwen, Colman, Howard, Holmen, Sheri L.

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Essential role for ras signaling in glioblastoma maintenance von HOLMEN, Sheri L, WILLIAMS, Bart O

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AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis von Kircher, David A., Trombetti, Kirby A., Silvis, Mark R., Parkman, Gennie L., Fischer, Grant M., Angel, Stephanie N., Stehn, Christopher M., Strain, Sean C., Grossmann, Allie H., Duffy, Keith L., Boucher, Kenneth M., McMahon, Martin, Davies, Michael A., Mendoza, Michelle C., VanBrocklin, Matthew W., Holmen, Sheri L.

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Melanoma models for the next generation of therapies von Patton, E. Elizabeth, Mueller, Kristen L., Adams, David J., Anandasabapathy, Niroshana, Aplin, Andrew E., Bertolotto, Corine, Bosenberg, Marcus, Ceol, Craig J., Burd, Christin E., Chi, Ping, Herlyn, Meenhard, Holmen, Sheri L., Karreth, Florian A., Kaufman, Charles K., Khan, Shaheen, Kobold, Sebastian, Leucci, Eleonora, Levy, Carmit, Lombard, David B., Lund, Amanda W., Marie, Kerrie L., Marine, Jean-Christophe, Marais, Richard, McMahon, Martin, Robles-Espinoza, Carla Daniela, Ronai, Ze'ev A., Samuels, Yardena, Soengas, Maria S., Villanueva, Jessie, Weeraratna, Ashani T., White, Richard M., Yeh, Iwei, Zhu, Jiyue, Zon, Leonard I., Hurlbert, Marc S., Merlino, Glenn

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Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases von Fischer, Grant M, Jalali, Ali, Kircher, David A, Lee, Won-Chul, McQuade, Jennifer L, Haydu, Lauren E, Joon, Aron Y, Reuben, Alexandre, de Macedo, Mariana P, Carapeto, Fernando C L, Yang, Chendong, Srivastava, Anuj, Ambati, Chandrashekar R, Sreekumar, Arun, Hudgens, Courtney W, Knighton, Barbara, Deng, Wanleng, Ferguson, Sherise D, Tawbi, Hussein A, Glitza, Isabella C, Gershenwald, Jeffrey E, Vashisht Gopal, Y N, Hwu, Patrick, Huse, Jason T, Wargo, Jennifer A, Futreal, P Andrew, Putluri, Nagireddy, Lazar, Alexander J, DeBerardinis, Ralph J, Marszalek, Joseph R, Zhang, Jianjun, Holmen, Sheri L, Tetzlaff, Michael T, Davies, Michael A

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Exploiting Drug Addiction Mechanisms to Select against MAPKi-Resistant Melanoma von Hong, Aayoung, Moriceau, Gatien, Sun, Lu, Lomeli, Shirley, Piva, Marco, Damoiseaux, Robert, Holmen, Sheri L, Sharpless, Norman E, Hugo, Willy, Lo, Roger S

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The role of PI3'‐lipid signalling in melanoma initiation, progression and maintenance von Parkman, Gennie L., Foth, Mona, Kircher, David A., Holmen, Sheri L., McMahon, Martin

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Aspirin Suppresses PGE2 and Activates AMP Kinase to Inhibit Melanoma Cell Motility, Pigmentation, and Selective Tumor Growth In Vivo von Kumar, Dileep, Rahman, Hafeez, Tyagi, Ethika, Liu, Tong, Li, Chelsea, Lu, Ran, Lum, David, Holmen, Sheri L., Maschek, J. Alan, Cox, James E., VanBrocklin, Matthew W., Grossman, Douglas

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Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity von Hong, Aayoung, Piva, Marco, Liu, Sixue, Hugo, Willy, Lomeli, Shirley H., Zoete, Vincent, Randolph, Christopher E., Yang, Zhentao, Wang, Yan, Lee, Jordan J., Lo, Skylar J., Sun, Lu, Vega-Crespo, Agustin, Garcia, Alejandro J., Shackelford, David B., Dubinett, Steven M., Scumpia, Philip O., Byrum, Stephanie D., Tackett, Alan J., Donahue, Timothy R., Michielin, Olivier, Holmen, Sheri L., Ribas, Antoni, Moriceau, Gatien, Lo, Roger S.

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APC inhibits ERK pathway activation and cellular proliferation induced by RAS von Park, Ki-Sook, Jeon, Soung Hoo, Kim, Sung-Eun, Bahk, Young-Yil, Holmen, Sheri L, Williams, Bart O, Chung, Kwang-Chul, Surh, Young-Joon, Choi, Kang-Yell

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