Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations von Trier, Cæcilie, Hollensted, Mette, Schnurr, Theresia M., Lund, Morten Asp Vonsild, Nielsen, Tenna Ruest Haarmark, Rui, Gao, Andersson, Ehm Astrid, Svendstrup, Mathilde, Bille, Dorthe Sadowa, Gjesing, Anette P., Fonvig, Cilius Esmann, Frithioff-Bøjsøe, Christine, Balslev-Harder, Marie, Quan, Shi, Gamborg, Michael, Pedersen, Oluf, Ängquist, Lars, Holm, Jens-Christian, Hansen, Torben

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Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus von Mahajan, Anubha, Sim, Xueling, Ng, Hui Jin, Manning, Alisa, Rivas, Manuel A, Highland, Heather M, Locke, Adam E, Grarup, Niels, Im, Hae Kyung, Cingolani, Pablo, Flannick, Jason, Fontanillas, Pierre, Fuchsberger, Christian, Gaulton, Kyle J, Teslovich, Tanya M, Rayner, N William, Robertson, Neil R, Beer, Nicola L, Rundle, Jana K, Bork-Jensen, Jette, Ladenvall, Claes, Blancher, Christine, Buck, David, Buck, Gemma, Burtt, Noël P, Gabriel, Stacey, Gjesing, Anette P, Groves, Christopher J, Hollensted, Mette, Huyghe, Jeroen R, Jackson, Anne U, Jun, Goo, Justesen, Johanne Marie, Mangino, Massimo, Murphy, Jacquelyn, Neville, Matt, Onofrio, Robert, Small, Kerrin S, Stringham, Heather M, Syvänen, Ann-Christine, Trakalo, Joseph, Abecasis, Goncalo, Bell, Graeme I, Blangero, John, Cox, Nancy J, Duggirala, Ravindranath, Hanis, Craig L, Seielstad, Mark, Wilson, James G, Christensen, Cramer, Brandslund, Ivan, Rauramaa, Rainer, Surdulescu, Gabriela L, Doney, Alex S F, Lannfelt, Lars, Linneberg, Allan, Isomaa, Bo, Tuomi, Tiinamaija, Jørgensen, Marit E, Jørgensen, Torben, Kuusisto, Johanna, Uusitupa, Matti, Salomaa, Veikko, Spector, Timothy D, Morris, Andrew D, Palmer, Colin N A, Collins, Francis S, Mohlke, Karen L, Bergman, Richard N, Ingelsson, Erik, Lind, Lars, Tuomilehto, Jaakko, Hansen, Torben, Watanabe, Richard M, Prokopenko, Inga, Dupuis, Josee, Karpe, Fredrik, Groop, Leif, Laakso, Markku, Pedersen, Oluf, Florez, Jose C, Morris, Andrew P, Altshuler, David, Meigs, James B, Boehnke, Michael, McCarthy, Mark I, Lindgren, Cecilia M, Gloyn, Anna L

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Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes von Niazi, Robina Khan, Sun, Jihua, Have, Christian Theil, Hollensted, Mette, Linneberg, Allan, Pedersen, Oluf, Nielsen, Jens Steen, Rungby, Jørgen, Grarup, Niels, Hansen, Torben, Gjesing, Anette Prior

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Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants von Sun, Jihua, Have, Christian Theil, Hollensted, Mette, Grarup, Niels, Linneberg, Allan, Pedersen, Oluf, Nielsen, Jens Steen, Rungby, Jørgen, Christensen, Cramer, Brandslund, Ivan, Kristiansen, Karsten, Jun, Wang, Hansen, Torben, Gjesing, Anette P

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Adults with pathogenic MC4R mutations have increased final height and thereby increased bone mass von Iepsen, Eva W., Zhang, Jinyi, Hollensted, Mette, Madsbad, Sten, Hansen, Torben, Holst, Jens J., Jørgensen, Niklas R., Holm, Jens-Christian, Torekov, Signe S.

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A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents von Nielsen, Tenna Ruest Haarmark, Appel, Emil Vincent Rosenbaum, Svendstrup, Mathilde, Ohrt, Johanne Dam, Dahl, Maria, Fonvig, Cilius Esmann, Hollensted, Mette, Have, Christian Theil, Kadarmideen, Haja N, Pedersen, Oluf, Hansen, Torben, Holm, Jens-Christian, Grarup, Niels

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Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity von Niazi, Robina Khan, Gjesing, Anette P, Hollensted, Mette, Have, Christian Theil, Grarup, Niels, Pedersen, Oluf, Ullah, Asmat, Shahid, Gulbin, Ahmad, Wasim, Gul, Asma, Hansen, Torben

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Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study von Hollensted, Mette, Ekstrøm, Claus T, Pedersen, Oluf, Eiberg, Hans, Hansen, Torben, Gjesing, Anette Prior

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Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report von Niazi, Robina Khan, Gjesing, Anette Prior, Hollensted, Mette, Have, Christian Theil, Borisevich, Dmitrii, Grarup, Niels, Pedersen, Oluf, Ullah, Asmat, Shahid, Gulbin, Shafqat, Ifrah, Gul, Asma, Hansen, Torben

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Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist von Iepsen, Eva W., Zhang, Jinyi, Thomsen, Henrik S., Hansen, Elizaveta L., Hollensted, Mette, Madsbad, Sten, Hansen, Torben, Holst, Jens J., Holm, Jens-Christian, Torekov, Signe S.

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Rare and low-frequency coding variants alter human adult height von Wood, Andrew R., Kjaer, Troels R., Lu, Yingchang, Thorleifsson, Gudmar, Turcot, Valérie, Young, Kristin L., Rivas, Manuel A., Abecasis, Goncalo, Aben, Katja K., Allin, Kristine H., Blüher, Matthias, Bots, Michiel L., Brilliant, Murray H., Carey, David J., Chambers, John C., Chasman, Daniel I., Chen, Yii-Der Ida, Chu, Audrey Y., Collins, Francis S., Cook, James P., de Groot, Mark C. H., de Mutsert, Renée, Ebeling, Tapani, Evangelou, Evangelos, Feng, Shuang, Ford, Ian, Fornage, Myriam, Gandin, Ilaria, Gordon, Scott D., Gustafsson, Stefan, Hattersley, Andrew T., Heid, Iris M., Helgeland, Øyvind, Hewitt, Alex W., Hovingh, G. Kees, Hoyng, Carel B., Huang, Paul L., Hveem, Kristian, Ikram, M. Arfan, Jansson, Jan-Håkan, Jarvik, Gail P., Jiang, Xuejuan, Jukema, J. Wouter, Kitajima, Hidetoshi, Kluivers, Kirsten B., Kontto, Jukka, Kooner, Jaspal S., Kriebel, Jennifer, Kuusisto, Johanna, Langenberg, Claudia, Lee, I-Te, Li, Huaixing, Lin, Honghuang, Lophatananon, Artitaya, Lyytikäinen, Leo-Pekka, Madden, Pamela A. F., Männistö, Satu, Mazul, Angela L., Metspalu, Andres, Mook-Kanamori, Dennis O., Morgan, Anna, Morris, Andrew P., Müller-Nurasyid, Martina, Nalls, Mike A., Nielsen, Sune F., Njølstad, Pål R., Palmer, Colin N. A., Pasterkamp, Gerard, Pedersen, Oluf, Perola, Markus, Perry, James A., Person, Thomas N., Salomaa, Veikko, Samani, Nilesh J., Sandow, Kevin, Schmidt, Marjanka K., Segura-Lepe, Marcelo P., Sim, Xueling, Small, Kerrin S., Southam, Lorraine, Steinthorsdottir, Valgerdur, Stumvoll, Michael, Tansey, Katherine E., Tardif, Jean-Claude, Taylor, Kent D., Thompson, Deborah J., Tyrer, Jonathan P., Uitterlinden, André G., van Schoor, Natasja M., Vozzi, Diego, Wang, Shuai, Wang, Yiqin, Wilson, James G., Young, Robin, Willer, Cristen J., Liu, Dajiang J., North, Kari E., Kutalik, Zoltán, Loos, Ruth J. F., Deloukas, Panos

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The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals von Banasik, Karina, Hollensted, Mette, Andersson, Ehm, Sparsø, Thomas, Sandbaek, Annelli, Lauritzen, Torsten, Jørgensen, Torben, Witte, Daniel R, Pedersen, Oluf, Hansen, Torben

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A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity von Bradfield, Jonathan P, Vogelezang, Suzanne, Felix, Janine F, Chesi, Alessandra, Helgeland, Øyvind, Horikoshi, Momoko, Karhunen, Ville, Lowry, Estelle, Cousminer, Diana L, Ahluwalia, Tarunveer S, Thiering, Elisabeth, Boh, Eileen Tai-Hui, Zafarmand, Mohammad H, Vilor-Tejedor, Natalia, Wang, Carol A, Joro, Raimo, Chen, Zhanghua, Gauderman, William J, Pitkänen, Niina, Parra, Esteban J, Fernandez-Rhodes, Lindsay, Alyass, Akram, Monnereau, Claire, Curtin, John A, Have, Christian T, McCormack, Shana E, Hollensted, Mette, Frithioff-Bøjsøe, Christine, Valladares-Salgado, Adan, Peralta-Romero, Jesus, Teo, Yik-Ying, Standl, Marie, Leinonen, Jaakko T, Holm, Jens-Christian, Peters, Triinu, Vioque, Jesus, Vrijheid, Martine, Simpson, Angela, Custovic, Adnan, Vaudel, Marc, Canouil, Mickaël, Lindi, Virpi, Atalay, Mustafa, Kähönen, Mika, Raitakari, Olli T, van Schaik, Barbera D C, Berkowitz, Robert I, Cole, Shelley A, Voruganti, V Saroja, Wang, Yujie, Highland, Heather M, Comuzzie, Anthony G, Butte, Nancy F, Justice, Anne E, Gahagan, Sheila, Blanco, Estela, Lehtimäki, Terho, Lakka, Timo A, Hebebrand, Johannes, Bonnefond, Amélie, Grarup, Niels, Froguel, Philippe, Lyytikäinen, Leo-Pekka, Cruz, Miguel, Kobes, Sayuko, Hanson, Robert L, Zemel, Babette S, Hinney, Anke, Teo, Koon K, Meyre, David, North, Kari E, Gilliland, Frank D, Bisgaard, Hans, Bustamante, Mariona, Bonnelykke, Klaus, Pennell, Craig E, Rivadeneira, Fernando, Uitterlinden, André G, Baier, Leslie J, Vrijkotte, Tanja G M, Heinrich, Joachim, Sørensen, Thorkild I A, Saw, Seang-Mei, Pedersen, Oluf, Hansen, Torben, Eriksson, Johan, Widén, Elisabeth, McCarthy, Mark I, Njølstad, Pål R, Power, Christine, Hyppönen, Elina, Sebert, Sylvain, Brown, Christopher D, Järvelin, Marjo-Riitta, Timpson, Nicholas J, Johansson, Stefan, Hakonarson, Hakon, Jaddoe, Vincent W V

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Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis von Viitasalo, Anna, Schnurr, Theresia M, Pitkänen, Niina, Hollensted, Mette, Nielsen, Tenna RH, Pahkala, Katja, Atalay, Mustafa, Lind, Mads V, Heikkinen, Sami, Frithioff-Bøjsøe, Christine, Fonvig, Cilius E, Grarup, Niels, Kähönen, Mika, Carrasquilla, Germán D, Larnkjaer, Anni, Pedersen, Oluf, Michaelsen, Kim F, Lakka, Timo A, Holm, Jens-Christian, Lehtimäki, Terho, Raitakari, Olli, Hansen, Torben, Kilpeläinen, Tuomas O

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Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model von Gao, Rui, Liu, Yanxia, Gjesing, Anette Prior, Hollensted, Mette, Wan, Xianzi, He, Shuwen, Pedersen, Oluf, Yi, Xin, Wang, Jun, Hansen, Torben

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Genetic Determinants of Weight Loss After Bariatric Surgery von Aasbrenn, Martin, Schnurr, Theresia Maria, Have, Christian Theil, Svendstrup, Mathilde, Hansen, Dorte Lindqvist, Worm, Dorte, Balslev-Harder, Marie, Hollensted, Mette, Grarup, Niels, Burgdorf, Kristoffer Sølvsten, Vestergaard, Henrik, Pedersen, Oluf, Sørensen, Thorkild I. A., Fenger, Mogens, Madsbad, Sten, Hansen, Torben

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14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes von Gjesing, Anette P, Engelbrechtsen, Line, Cathrine B Thuesen, Anne, Have, Christian T, Hollensted, Mette, Grarup, Niels, Linneberg, Allan, Steen Nielsen, Jens, Christensen, Lotte B, Thomsen, Reimar W, Johansson, Kristoffer E, Cagiada, Matteo, Gersing, Sarah, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten, Vaag, Allan, Sørensen, Henrik T, Brandslund, Ivan, Beck-Nielsen, Henning, Pedersen, Oluf, Rungby, Jørgen, Hansen, Torben

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Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children von Hollensted, Mette, Fogh, Mette, Schnurr, Theresia M., Kloppenborg, Julie T., Have, Christian T., Ruest Haarmark Nielsen, Tenna, Rask, Johanne, Asp Vonsild Lund, Morten, Frithioff‐Bøjsøe, Christine, Østergaard Johansen, Mia, Vincent Rosenbaum Appel, Emil, Mahendran, Yuvaraj, Grarup, Niels, Kadarmideen, Haja N., Pedersen, Oluf, Holm, Jens‐Christian, Hansen, Torben

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An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are ov... von Graae, Anne-Sofie, Hollensted, Mette, Kloppenborg, Julie T., Mahendran, Yuvaraj, Schnurr, Theresia M., Appel, Emil Vincent R., Rask, Johanne, Nielsen, Tenna R. H., Johansen, Mia Ø., Linneberg, Allan, Jørgensen, Marit E., Grarup, Niels, Kadarmideen, Haja N., Holst, Birgitte, Pedersen, Oluf, Holm, Jens-Christian, Hansen, Torben

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Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents von Viitasalo, Anna, Schnurr, Theresia M., Pitkänen, Niina, Hollensted, Mette, Nielsen, Tenna R. H., Pahkala, Katja, Lintu, Niina, Lind, Mads V., Atalay, Mustafa, Frithioff-Bøjsøe, Christine, Fonvig, Cilius E., Grarup, Niels, Kähönen, Mika, Larnkjaer, Anni, Pedersen, Oluf, Holm, Jens-Christian, Michaelsen, Kim F., Lakka, Timo A., Lehtimäki, Terho, Raitakari, Olli, Hansen, Torben, Kilpeläinen, Tuomas O.

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