The Central Role of the Alternative Complement Pathway in Human Disease von Thurman, Joshua M, Holers, V. Michael

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Antibodies against citrullinated proteins enhance tissue injury in experimental autoimmune arthritis von Kuhn, Kristine A, Kulik, Liudmila, Tomooka, Beren, Braschler, Kristin J, Arend, William P, Robinson, William H, Holers, V Michael

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Predicting and preventing the development of rheumatoid arthritis von Raza, Karim, Klareskog, Lars, Holers, V Michael

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Arthritis Critically Dependent on Innate Immune System Players von Ji, Hong, Ohmura, Koichiro, Mahmood, Umar, Lee, David M, Hofhuis, Frans M.A, Boackle, Susan A, Takahashi, Kazue, Holers, V.Michael, Walport, Mark, Gerard, Craig, Ezekowitz, Alan, Carroll, Michael C, Brenner, Michael, Weissleder, Ralph, Verbeek, J.Sjef, Duchatelle, Veronique, Degott, Claude, Benoist, Christophe, Mathis, Diane

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Complement C3 activation is required for antiphospholipid antibody-induced fetal loss von Holers, V Michael, Girardi, Guillermina, Mo, Lian, Guthridge, Joel M, Molina, Hector, Pierangeli, Silvia S, Espinola, Ricardo, Xiaowei, Liu E, Mao, Dailing, Vialpando, Christopher G, Salmon, Jane E

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Disruptive innovation in rheumatology: new networks of global public-private partnerships are needed to take advantage of scientific progress von Huizinga, TWJ, Holers, VM, Anolik, J, Brenner, MB, Buckley, CD, Bykerk, V, Connolly, SE, Deane, KD, Guo, J, Hodge, M

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Lack of a Functional Alternative Complement Pathway Ameliorates Ischemic Acute Renal Failure in Mice von Thurman, Joshua M, Ljubanovic, Danica, Edelstein, Charles L, Gilkeson, Gary S, Holers, V. Michael

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A Critical Role for Murine Complement Regulator Crry in Fetomaternal Tolerance von Xu, Chenguang, Mao, Dailing, Holers, V. Michael, Palanca, Ben, Cheng, Alec M., Molina, Hector

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Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection von Atkinson, Carl, Song, Hongbin, Lu, Bo, Qiao, Fei, Burns, Tara A, Holers, V Michael, Tsokos, George C, Tomlinson, Stephen

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The complement system as a therapeutic target in autoimmunity von Holers, V.Michael

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Acute tubular necrosis is characterized by activation of the alternative pathway of complement von Thurman, Joshua M., Scott Lucia, M., Ljubanovic, Danica, Michael Holers, V.

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The interrelationship of complement‐activation fragments and angiogenesis‐related factors in early pregnancy and their association with pre‐eclampsia von Lynch, AM, Murphy, JR, Gibbs, RS, Levine, RJ, Giclas, PC, Salmon, JE, Holers, VM

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Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion von Thurman, Joshua M, Ljubanović, Danica, Royer, Pamela A, Kraus, Damian M, Molina, Hector, Barry, Nicholas P, Proctor, Gregory, Levi, Moshe, Holers, V Michael

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Timing of elevations of autoantibody isotypes in rheumatoid arthritis prior to disease diagnosis von Kelmenson, LB, Wagner, BD, McNair, BK, Frazer-Abel, A, Demoruelle, KM, Bergstedt, DT, Feser, ML, Moss, LK, Parish, MC, Mewshaw, EA, Mikuls, TR, Edison, JD, Holers, VM, Deane, KD

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Immunoglobulin-driven complement activation regulates pro-inflammatory remodeling in pulmonary hypertension von Frid, MG, McKeon, BA, Thurman, JM, Maron, BA, Li, M, Zhang, H, Kumar, S, Sullivan, T, Laskowsky, J, Fini, MA, Hu, S, Tuder, RM, Gandjeva, A, Wilkins, MR, Rhodes, CJ, Ghataorhe, P, Leopold, JA, Wang, R-S, Holers, VM, Stenmark, KR

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Anti-C1q autoantibodies amplify pathogenic complement activation in systemic lupus erythematosus von Holers, V Michael

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A novel inhibitor of the alternative complement pathway prevents antiphospholipid antibody-induced pregnancy loss in mice von Thurman, Joshua M., Kraus, Damian M., Girardi, Guillermina, Hourcade, Dennis, Kang, Hee J., Royer, Pamela A., Mitchell, Lynne M., Giclas, Patricia C., Salmon, Jane, Gilkeson, Gary, Holers, V. Michael

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Cr2, a Candidate Gene in the Murine Sle1c Lupus Susceptibility Locus, Encodes a Dysfunctional Protein von Boackle, Susan A, Holers, V.Michael, Chen, Xiaojiang, Szakonyi, Gerda, Karp, David R, Wakeland, Edward K, Morel, Laurence

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The alternative pathway of complement in disease: opportunities for therapeutic targeting von Holers, V.Michael, Thurman, Joshua M

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The structure of human CD23 and its interactions with IgE and CD21 von Hibbert, Richard G, Teriete, Peter, Grundy, Gabrielle J, Beavil, Rebecca L, Reljic, Rajko, Holers, V Michael, Hannan, Jonathan P, Sutton, Brian J, Gould, Hannah J, McDonnell, James M

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