Normal Hematopoietic Progenitor Subsets Have Distinct Reactive Oxygen Species, BCL2 and Cell-Cycle Profiles That Are Decoupled from Maturation in Acute Myeloid Leukemia von Khan, Naeem, Hills, Robert K, Knapper, Steve, Steadman, Lora, Qureshi, Ushna, Rector, Jerrald L, Bradbury, Charlotte, Russell, Nigel H, Vyas, Paresh, Burnett, Alan K, Grimwade, David, Hole, Paul S, Freeman, Sylvie D

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Reactive Oxygen Species Drive Proliferation in Acute Myeloid Leukemia via the Glycolytic Regulator PFKFB3 von Robinson, Andrew J., Hopkins, Goitseone L., Rastogi, Namrata, Hodges, Marie, Doyle, Michelle, Davies, Sara, Hole, Paul S., Omidvar, Nader, Darley, Richard L., Tonks, Alex

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Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants von Agathanggelou, Angelo, Weston, Victoria J, Perry, Tracey, Davies, Nicholas J, Skowronska, Anna, Payne, Daniel T, Fossey, John S, Oldreive, Ceri E, Wei, Wenbin, Pratt, Guy, Parry, Helen, Oscier, David, Coles, Steve J, Hole, Paul S, Darley, Richard L, McMahon, Michael, Hayes, John D, Moss, Paul, Stewart, Grant S, Taylor, A Malcolm R, Stankovic, Tatjana

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Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling von Hole, Paul S., Zabkiewicz, Joanna, Munje, Chinmay, Newton, Zarabeth, Pearn, Lorna, White, Paul, Marquez, Nuria, Hills, Robert K., Burnett, Alan K., Tonks, Alex, Darley, Richard L.

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Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia von Alanazi, Bader, Munje, Chinmay R., Rastogi, Namrata, Williamson, Andrew J. K., Taylor, Samuel, Hole, Paul S., Hodges, Marie, Doyle, Michelle, Baker, Sarah, Gilkes, Amanda F., Knapper, Steven, Pierce, Andrew, Whetton, Anthony D., Darley, Richard L., Tonks, Alex

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Interleukin‐5 drives glycolysis and reactive oxygen species‐dependent citric acid cycling by eosinophils von Jones, Nicholas, Vincent, Emma E., Felix, Lindsey C., Cronin, James G., Scott, Louis M., Hole, Paul S., Lacy, Paige, Thornton, Catherine A.

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Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: An optimised protocol for digital flow cytometers von Wadley, Alex J., Morgan, Rhys G., Heesom, Kate J., Hole, Paul S., Coles, Steven J.

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Ras-induced reactive oxygen species promote growth factor–independent proliferation in human CD34+ hematopoietic progenitor cells von Hole, Paul S., Pearn, Lorna, Tonks, Amanda J., James, Philip E., Burnett, Alan K., Darley, Richard L., Tonks, Alex

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Using Flow Cytometry to Detect and Measure Intracellular Thiol Redox Status in Viable T Cells from Heterogeneous Populations von Wadley, Alex J., Morgan, Rhys G., Darley, Richard L., Hole, Paul S., Coles, Steven J.

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Analysis of ROS-Responsive Genes in Mutant RAS Expressing Hematopoietic Progenitors Identifies the Glycolytic Pathway As a Major Target Promoting Both Proliferation and Survival von Hopkins, Goitseone Lucy, Robinson, Andrew J, Hole, Paul S, Darley, Richard L., Tonks, Alex

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A Subpopulation of Blasts with Attenuated p38MAPK Response Is Seen in Virtually All AML Patients and AML Cell Lines and Is Defined By Cells with Augmented Lipid-Associated Anti-Oxi... von Hole, Paul S., Davies, Sara, Munje, Chinmay R, Kreuser, Sandra, Hills, Robert K., Omidvar, Nader, Knapper, Steven, Burnett, Alan K., Tonks, Alex, Darley, Richard L.

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Ras Promotes Production of Reactive Oxygen Species in Normal Human CD34+ Cells: Role in Promoting Cell Survival and Protein Phosphorylation von Hole, Paul S, Pearn, Lorna, James, Philip E, Burnett, Alan, Darley, Richard L, Tonks, Alex

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Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: An optimised protocol for digital flow cytometers von Alex Wadley, Rhys G. Morgan, Kate J. Heesom, Paul S. Hole, Steven J. Coles

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Do reactive oxygen species play a role in myeloid leukemias? von Hole, Paul Spencer, Darley, Richard Lawrence, Tonks, Alex

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Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis von Dragovic, Rebecca A., MSc, Gardiner, Christopher, PhD, Brooks, Alexandra S., MD, Tannetta, Dionne S., PhD, Ferguson, David J.P., PhD, Hole, Patrick, PhD, Carr, Bob, PhD, Redman, Christopher W.G., MD, FRCP, Harris, Adrian L., MD, PhD, FRCP, Dobson, Peter J., PhD, FInstP, CPhys, Harrison, Paul, PhD, Sargent, Ian L., PhD

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An alternative suggestion for the Pliocene onset of major northern hemisphere glaciation based on the geochemical provenance of North Atlantic Ocean ice-rafted debris von Bailey, Ian, Hole, Georgia M., Foster, Gavin L., Wilson, Paul A., Storey, Craig D., Trueman, Clive N., Raymo, Maureen E.

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Understanding a high-risk acute myeloid leukemia by analyzing the interactome of its major driver mutation von Chiriches, Claudia, Nicolaisen, Nathalie, Wieske, Maria, Elhaddad, Heba, Mehmetbeyoglu, Ecmel, Alvares, Caroline, Becher, Dörte, Hole, Paul, Ottmann, Oliver Gerhard, Ruthardt, Martin

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The Effect of Postoperative Face-Down Positioning and of Long- versus Short-Acting Gas in Macular Hole Surgery: Results of a Registry-Based Study von Essex, Rohan W, Kingston, Zabrina S, Moreno-Betancur, Margarita, Shadbolt, Bruce, Hunyor, Alex P, Campbell, William G, Connell, Paul P, McAllister, Ian L

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Characterization of IL-22 and antimicrobial peptide production in mice protected against pulmonary Cryptococcus neoformans infection von Wozniak, Karen L, Hole, Camaron R, Yano, Junko, Fidel, Paul L, Wormley, Floyd L

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Dialysis initiation, modality choice, access, and prescription: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference von Chan, Christopher T., Blankestijn, Peter J., Dember, Laura M., Gallieni, Maurizio, Harris, David C.H., Lok, Charmaine E., Mehrotra, Rajnish, Stevens, Paul E., Wang, Angela Yee-Moon, Cheung, Michael, Wheeler, David C., Winkelmayer, Wolfgang C., Pollock, Carol A., Abu-Alfa, Ali K., Bargman, Joanne M., Bleyer, Anthony J., Brown, Edwina A., Davenport, Andrew, Davies, Simon J., Finkelstein, Frederic O., Flythe, Jennifer E., Goffin, Eric, Golper, Thomas A., Gómez, Rafael, Hamano, Takayuki, Hecking, Manfred, Heimbürger, Olof, Hole, Barnaby, Hothi, Daljit K., Ikizler, T. Alp, Isaka, Yoshitaka, Iseki, Kunitoshi, Jha, Vivekanand, Kawanishi, Hideki, Kerr, Peter G., Komenda, Paul, Kovesdy, Csaba P., Lacson, Ed, Laville, Maurice, Lee, Jung Pyo, Lerma, Edgar V., Levin, Nathan W., Lichodziejewska-Niemierko, Monika, Liew, Adrian, Lindley, Elizabeth, Lockridge, Robert S., Madero, Magdalena, Massy, Ziad A., McCann, Linda, Meyer, Klemens B., Morton, Rachael L., Nadeau-Fredette, Annie-Claire, Okada, Hirokazu, Perez, Jose, Perl, Jeff, Polkinghorne, Kevan R., Riella, Miguel C., Robinson, Bruce M., Rocco, Michael V., Rosansky, Steven J., Rotmans, Joris I., Fernanda Slon Roblero, María, Tangri, Navdeep, Tonelli, Marcello, Tong, Allison, Tsukamoto, Yusuke, Tungsanga, Kriang, Vachharajani, Tushar J., van Loon, Ismay, Watnick, Suzanne, Weiner, Daniel E., Wilkie, Martin, Zakharova, Elena

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